Cuteness is commonly associated with visual features such as large eyes, a disproportionately large head, round body shapes, and small size. While these traits are most often observed in infants and young animals, they also appear in inanimate objects and digital representations intentionally designed to evoke emotional appeal. Drawing on developmental psychology, behavioral science, neuroscience, and cultural studies, this paper examines five core emotional responses to cute stimuli: caretaking, socializing, whimsical, cute aggression, and kama muta (the feeling of being emotionally moved). These responses emerge from an interplay between evolutionary mechanisms, such as caregiving instincts, and cultural frameworks that shape how cuteness is perceived, expressed, and valued. The analysis highlights not only biological foundations but also cultural moderators, with particular attention to gender differences and the pervasive role of kawaii aesthetics in Japan’s popular culture, communication, and everyday life. This paper provides an overview of these emotional responses, situates them within their theoretical foundations and broader psychological and social implications, and proposes a framework for future research.