Please note this is a comparison between Version 2 by Rita Xu and Version 4 by Rita Xu.
The complex anatomy of the eye presents a major challenge in the treatment of posterior segment eye diseases, hindering the effective delivery of medications. Conventional treatments, including topical eye drops and intravitreal injections, are limited by poor bioavailability and short residence time, necessitating frequent dosing to manage the disease. Intravitreal injections can also lead to serious ocular complications. Biodegradable nano-based drug delivery systems (DDSs) have emerged as a potential solution to these limitations, offering longer residence time in ocular tissues and better penetration through ocular barriers. Furthermore, the biodegradable polymers used to create these systems are nanosized, reducing the risk of toxicity and adverse reactions.
ocular surface disease
retinal disease
nanosystems for ocular drug delivery
nanocarriers
biodegradable polymers
ocular drug delivery system
hydrogels
ocular inserts
exosomes
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References
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