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METHICILLIN-SUSCEPTIBLE Staphylococcus aureus: Comparison
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Please note this is a comparison between Version 2 by Karina Chen and Version 1 by Shakti Regmi.

Background: Antibiotic resistance is a global health challenge nowadays, and methicillin-sensitive Staphylococcus aureus (MSSA) is a skin infection presents as pimples, boils, abscesses, or infected cuts and is not resistant to certain antibiotics. MSSA affects people of all ages and is known to cause epidemics among sports teams, families, prison inmates, and people who live and work in close quarters and is a global health challenge nowadays, creating problems in antibiotic therapy. This study has aimed to generate a resistance pattern of MSSA to various antibiotics to formulate antibiotic policy for the control of Methicillin-resistant Staphylococcus aureus in Nepal. Method: We studied the patients of all clinical units having MSSA infections from children and adults of all ages from March to September 2018 at the Everest Hospital, Kathmandu, Nepal. A total of 526 samples were isolated and identified using the disc diffusion method followed by the given guidelines from the Clinical and Laboratory Standards Institute (CLSI 2015). Result: A total of 526 non-repeated, clinical samples subjected to culture from both Inpatient and Outpatient over 6 months included to generate data. From the total clinical samples cultured, the highest number of samples, i.e., 177(33.6%) shows significant growth, 60 (33.8%) showed positive S. aureus growth. However, 89.7% of S. aureus was isolated from pus. Antibiotic sensitivity pattern showed all Methicillin Sensitive Staphylococcus aureus (MSSA) isolates were sensitive to Vancomycin. MSSA showed the highest resistance to Clotrimazole (43.1%) and less resistance to Cephalexin (22.7%), followed by Gentamycin (27.2%). MSSA was cent-percent sensitive to Vancomycin. Conclusion: The prevalence of MSSA has been found to be 33.8%, and all Staphylococcus aureus appears 100% sensitive to Vancomycin.

Antibiotic resistance is a global health challenge nowadays, and methicillin-sensitive Staphylococcus aureus (MSSA) is a skin infection presents as pimples, boils, abscesses, or infected cuts and is not resistant to certain antibiotics. MSSA affects people of all ages and is known to cause epidemics among sports teams, families, prison inmates, and people who live and work in close quarters and is a global health challenge nowadays, creating problems in antibiotic therapy.

  • Vancomycin
  • MSSA
  • Staphylococcus aureus
  • Prevalence
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