Probiotic Potential of Lactiplantibacillus plantarum and its Fermented Foods: Comparison
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植物乳杆菌 （Lb. plantarum）是一种广泛分布于发酵食品和人体肠道中的乳酸菌（ is a kind of lactic acid bacteria (LAB），其中部分菌株对人体健康有重要影响，并有可能发展成为益生菌。它可以在分子、细胞和种群水平上调节机体的新陈代谢，从而降低血糖和血脂，调节血压。) widely distributed in fermented food and the human intestinal tract, some strains of which have important effects on human health and the potential to be developed into probiotics.

  • Lactiplantibacillus plantarum
  • fermentation
  • probiotic functional foods

11. Probiotic Potential of Lb. plantarum and Foods Fermented with It

Lb的益生菌潜力。植物 和用它发酵的食物

磅。. plantarum 植物属于belongs to the genus 乳酸杆菌属，被广泛认为是一种益生菌，从物种分析来看可能具有益生菌潜力。然而，益生菌在宿主胃肠道中发挥作用的先决条件是对胃酸、胆汁盐和降解酶等不利因素的良好耐受性，以及在胃肠道中完成定植的能力[Lactobacillus, which is widely considered to be a probiotic, and may have probiotic potential from species analysis. However, a prerequisite for probiotics to function in the host’s gastrointestinal tract is a good tolerance to unfavorable factors such as gastric acid, bile salts, and degrading enzymes, as well as the ability to complete colonization in the gastrointestinal tract 14[1]. ]。因此，Therefore,  LB。植物b. plantarum 必须具有较高的胃肠道存活率才能满足作为益生菌发育的基本要求。must have a high gastrointestinal survival rate to meet the basic requirements for development as a probiotic. Kriti Ghatani 和and Buddhiman Tamang [[2] isolated 15a ]strain 分离出一株of Lb。植物. plantarum 从发酵牦牛乳制品中提取，然后在from fermented yak milk products, and then added cholesterol and bile salts to MRS 肉汤中加入胆固醇和胆汁盐，以确定所选菌株的耐受性。结合耐酸性、胆汁盐水解酶活性和细胞表面疏水性，他们证实了这一菌株的broth to determine the tolerance of the selected strain. Combined with acid resistance, bile salt hydrolase activity and cell surface hydrophobicity, they confirmed that this strain of Lb. 植物plantarum 对人的胃酸和胆汁的腐蚀和毒性作用具有耐受性，可以粘附宿主细胞完成定植。was tolerant to the corrosive and toxic effects of gastric acid and bile in humans, and can adhere to host cells to complete colonization. Wang, GQ 和.Q. and Chen, Y. et al. [3] recorded 等人。[the images of mouse intestines at different times after 16oral ]administration 记录了口服of Lb后不同时间小鼠肠道的图像。植物，确认. plantarum, confirming that Lb。植物. plantarum AR17-1 可以在肠道中定殖并发挥作用，这意味着can colonize and play a role in the intestinal tract, implying that Lb. 植物plantarum 具有益生菌潜力。has probiotic potential.
作为As a carrier for Lb的载体。植物. plantarum 进入人体，to enter the human body,  Lb。具有高活菌数的植物发酵食品有可能被开发成可以在人体中发挥健康作用的益生菌食品。然而，这些发酵食品作为益生菌食品的功能还取决于食品中益生菌的胃肠道存活率。不同的食物基质对. plantarum-fermented foods with high live counts have the potential to be developed into probiotic foods that can play a healthy role in the human body. However, the ability of these fermented foods to function as probiotic foods also depends on the gastrointestinal survival of the probiotic bacteria in the food. Different food matrices also have significant impacts on the gastrointestinal survival rate of Lb的胃肠道存活率也有显着影响 。植物。最广泛使用的基质是乳制品，包括酸奶、奶酪等。乳制品中较高的脂肪和乳清蛋白含量使其对胃酸的缓冲能力更好，可以提高益生菌的胃肠道存活率[. plantarum. The most widely used matrices are dairy products including yogurt, cheese, etc. The higher fat and whey protein content in dairy products result in their better buffering capacity against gastric acid, which can improve the gastrointestinal survival rate of probiotics [4][5]. In addition, other fermented foods, such as fruit and vegetable juices, oats and 17cereals, 18and meat products are also commonly used as food matrices to create fermented foods that bring probiotics into the human gastrointestinal tract. The fat in meat products protects probiotics from ]。此外，其他发酵食品，如水果和蔬菜汁、燕麦和谷类食品以及肉制品也常被用作食品基质，以制造将益生菌带入人体胃肠道的发酵食品。肉制品中的脂肪可以保护益生菌免受低low pH 值和胆汁盐的影响and bile salts [5], the higher sugar content in [cereals 18allows ]，谷物中较高的糖分使益生菌能够更好地耐受肠道条件probiotics [to 19better ]，而果蔬汁相对较短的消化时间可以大大减少不良反应。胃环境对益生菌的影响tolerate [intestinal 20conditions [6], 21and the relatively short digestion time of fruit and vegetable juices can greatly reduce the adverse effects of the gastric environment on probiotics [7][8]. ]。当前Current 磅。植物Lb. plantarum-fermented 可能具有益生菌潜力的发酵食品包括乳制品、肉制品、豆制品、水果和蔬菜以及谷物，其中foods that may have probiotic potential include dairy products, meat products, soy products, fruits and vegetables, and cereals, where the gastrointestinal survival of Lb。植物。. plantarum. 高。不过，关于食物基质对益生菌胃肠道存活率影响的研究还比较少，希望以后有更多的研究集中在这方面。is high. However, studies on the effect of food matrices on the gastrointestinal survival rate of probiotics are still relatively few, and it is hoped that more research will focus on this in the future.

22. Recent Developments in Lb. Lb的最新发展。植物plantarum-发酵食品Fermented Food

如上所述，As mentioned above,  Lb。植物. plantarum has the potential to be developed as a probiotic because of its excellent anti-cardiovascular properties, as well as its good tolerance in the gastrointestinal tract, which is important for human health. In addition, some studies have demonstrated that foods fermented with it have better health benefits than before fermentation, and may have the ability to be developed into probiotic functional foods. The applications of 具有被开发为益生菌的潜力，因为它具有出色的抗心血管特性，以及在胃肠道中的良好耐受性，这对人类健康很重要。此外，一些研究表明，用它发酵的食品比发酵前有更好的健康益处，可能有能力发展成益生菌功能食品。Lb的应用. plantarum 。植物in different types of foods, and the corresponding effects of its fermented foods, are shown in 在不同种类食品中的作用，以及其发酵食品的相应作用， 见图Figure 1 和and 表Table 1。.
食品 11 02549 g005 550
Figure 1. The application of Lactiplantibacillus plantarum  in several different types of food. Lactiplantibacillus plantarum has been widely used as a fermenting strain in the production of a wide range of fermented foods. (Created with Biorender.com).
Table 1. The effects of Lb. plantarum fermented foods in the prevention of different diseases.
Types of Food Fermented Food Lb. plantarum Function Mechanism References
Fruit and

vegetable juice		 charantia juice Lb. plantarum NCU116 antioxidant increase the content of phenolic compounds and promote the biotransformation to provide stronger antioxidant properties [124][9]
  papaya juice Lb. plantarum GIM1.140 antioxidant increase the content of total flavonoids and improve inhibition of DPPH free radicals [125][10]
  blueberry juice A variety of mixed strains including Lb. plantarum anti-diabetes maintain glucose homeostasis and promote glucose consumption [126][11]
  green loofah Lb. plantarum SU4 cholesterol

lowering		 high bile acid lowering capacity in vitro and in vivo to promote cholesterol consumption [127][12]
Aquatic

product		 laminaria japonica Lb. plantarum FZU3013 cholesterol

lowering		 reduce expression levels of genes involved in lipid metabolism and bile acid homeostasis to promote cholesterol consumption [128][13]
Soybean

products		 black Soymilk Lb. plantarum BCRC 10357 antioxidant increase the ferric reducing antioxidant capacity [129][14]
  soy milk added with cuminum cyminum essential oil Lb. plantarum

A7 (KC 355240)		 anti-diabetes

and

cholesterol

lowering		 significantly reduces postprandial serum glucose concentrations and TG levels. [130][15]
  soy extract Lb. plantarum WW cholesterol

lowering		 regulate the expression levels of genes involved in lipid metabolism and oxidation-reduction processes to promote cholesterol catabolism [131][16]
Dairy

products		 orange juice-milk

based beverage		 Lb. plantarum (TR-7, TR-71, TR-14) antioxidant increase the content of carotenoids and the total antioxidant activity [132][17]
  kalari cheese Lb. plantarum NCDC 012 anti-diabetes produce a variety of bioactive peptides to enhance the inhibitory activity of α-amylase and α-glucosidase, and inhibit carbohydrate decomposition to lower glucose [133][18]
  goat milk Lb. plantarum C4 blood pressure lowering enhance the ACE inhibitory activity by fermentation [134][19]
  skim milk Lb. plantarum WW cholesterol

lowering		 regulate the intestinal flora and lower cholesterol levels [135][20]
  cheese Lb. plantarum VC213 cholesterol

lowering		 significantly lower cholesterol content than before fermentation [136][21]
Cereal grains rice bran and

wheat bran		 Lb. plantarum NCU116 antioxidant enhance the hydroxyl radical-scavenging activity and the oxygen radical-quenching activity [137][22]
  whole-grain oats Lb. plantarum B1-6 blood pressure lowering present higher ACE inhibitory activities [138][23]
Meat

products		 Chinese fermented sausages Lb. plantarum CD101 antioxidant reduce pH, and promote the formation of antioxidant peptides [139][24]
  fermented meat patty Lb. plantarum PTCC 1745 antioxidant radical scavenging activity significantly higher than before fermentation [140][25]
  fermented camel sausages Lb. plantarum KX881772 anti-diabetes higher α-amylase and higher α-glucosidase inhibitions to control diabetes by reducing carbohydrate hydrolysis [141][26]
  fermented sausage Lb. plantarum CD101 blood pressure lowering significantly increase the ACE inhibitory activity [142][27]

2.1. Fermented Food with Antioxidant Function

Fruits and vegetables are rich in phenolic substances, carotenoids, flavonoids, and vitamin C, which have good antioxidant effects. Therefore, scientists hope to develop functional beverages based on fruit and vegetable juices and improve their antioxidant capacity through fermentation. In earlier research, some fermented juices with antioxidant functions, such as apple, orange, jujube, and coconut juices have been produced and proven to have a better ability to scavenge free radicals. In recent years, there have also been many reports on the antioxidant functional juice fermented by Lb. plantarum. Wu, Li, et al. [143][28] compared the antioxidant activity of blueberry and blackberry juices before and after fermentation based on ABTS methods, and they found that the ABTS radical scavenging activity of blackberry and blueberry juices fermented with Lactobacillus plantarum increased by 53.3% and 64.0%, respectively, compared to the juice before fermentation. The same results were also reported in fermented vegetable juice. Zhang, Duan, et al. [144][29] also found that the DPPH radical scavenging rate and ABTS free radical scavenging rate of carrot juice after 72 h of fermentation by Lb. plantarum WZ-01 were increased to some extent compared to their pre-fermentation state. These results suggest that fermentation by Lb. plantarum can effectively enhance the free radical scavenging activity of juices, and fermented fruit and vegetable juices can be developed as a good antioxidant functional beverage.
In addition to fruit and vegetable juice, there are also reports on the application of Lb. plantarum in the fermentation of other types of foods, including dairy products [132][17], soybean products [129][14], fermented sausages [139][24]. All these types of fermented foods show better antioxidant capacity in vitro compared with prior to fermentation.

2.2. Fermented Food with Cholesterol-Lowering Function

The development of Lb. plantarum-fermented foods with cholesterol-lowering effects have achieved some results, including dairy products, soybean products, fruits and vegetables, aquatic products. As early as 2015, Jeon, Lee, et al. [145][30] isolated a strain of lactic acid bacteria from kimchi that could lower cholesterol in vitro, named Lb. plantarum EM. Four years later, they utilized Lb. plantarum EM as a fermenting strain in cabbage-apple juice to investigate the health-promoting effects of fermented juice on high-cholesterol diet rats. It was found that the serum levels of TG, TC, and LDL-C were greatly reduced, and HDL-C levels were increased in rats fed with fermented juice compared to unfermented juice. Many scientists have obtained similar results with different types of fermented foods. Cao, Wu, et al. [131][16] pointed out that soy extract fermented by Lb. plantarum could regulate lipid metabolism through signaling pathways and thus lower cholesterol. Li, Wu, et al. [135][20] analyzed the microbial diversity of rat feces and found that skim milk fermented with Lb. plantarum WW could regulate intestinal flora and lower cholesterol levels. Hu, Zheng, et al. [128][13] found that Lb. plantarum FZU3013-fermented Laminaria japonica could affect the expression of genes involved in lipid metabolism and bile acid homeostasis in rats.

2.3. Fermented Food with Blood Pressure Lowering Function

There are few reports on the hypotensive effects of Lb. plantarum-fermented foods, and most of those reports focused on fermented foods that can inhibit ACE activity and are mainly fermented dairy products. In addition to dairy products, the same findings have been reported for other fermented foods, such as soy milk [71][31], fermented sausages [146][32], and fruits like guava [147][33]. However, due to the lack of relevant studies, it cannot be ascertained whether fermented foods are effective in in vivo experiments.

2.4. Fermented Food with Hypoglycemic Function

Several studies have confirmed the hypoglycemic effect of Lb. plantarum-fermented foods. Zhong, Abdullah, et al. [126][11] used blueberry as a fermentation substrate. Blueberries are widely considered to have a good antidiabetic ability and the potential to treat early-stage diabetes. In their research, they found that, compared with the non-fermented blueberry juice, the fumarate contents in blueberry juice fermented by Lb. plantarum were significantly increased, which could maintain glucose homeostasis. In addition, fermentation altered the concentrations of phenolic compounds in blueberry juice, which promoted glucose consumption. They employed HepG2 cell lines as a model to confirm that fermented juice significantly enhanced cellular glucose consumption [148][34]. In addition to this, Lb. plantarum fermentation also increases α-Amylase and α-glucosidase inhibitory activity, thus reducing carbohydrate hydrolysis for the effective control of diabetes [149][35].

2.5. Other Applications of Lb. plantarum

In conclusion, it can be seen that Lb. plantarum-fermented foods show good effects in in vitro experiments, and have the potential to be developed into probiotic products. Moreover, in addition to conferring additional functional characteristics to the foods, Lb. plantarum fermentation may improve the properties of traditional fermented foods. Compared with unfermented food, fermented food can produce bacteriocins with good antimicrobial properties and extended storage time [150][36]; it may also have better stability [151][37], and its flavor will be improved to meet consumers’ demands [9]. At present, there are various kinds of functional fermented foods reported covering [124]。目前报道的功能性发酵食品种类繁多，涵盖基本饮食，如乳制品、水果、蔬菜、肉制品、大豆、谷类等。这些因素综合表明，发展中的 the basic diet, such as dairy products, fruits, vegetables, meat products, soybeans, and cereals. These factors comprehensively show that developing Lb。植物发酵食品并在日常生活中补充这些食品可能对人类健康具有重要意义。. plantarum-fermented foods and supplementing these foods in daily life may be of great significance to human health.

References

  1. Han, S.; Lu, Y.; Xie, J.; Fei, Y.; Zheng, G.; Wang, Z.; Liu, J.; Lv, L.; Ling, Z.; Berglund, B.; et al. Probiotic Gastrointestinal Transit and Colonization After Oral Administration: A Long Journey. Front. Cell. Infect. Microbiol. 2021, 11, 609722.
  2. Ghatani, K.; Tamang, B. Assessment of probiotic characteristics of lactic acid bacteria isolated from fermented yak milk products of Sikkim, India: Chhurpi, Shyow, and Khachu. Food Biotechnol. 2017, 31, 210–232.
  3. Wang, G.; Chen, Y.; Fei, S.; Xie, C.; Xia, Y.; Ai, L. Colonisation with endogenous Lactobacillus reuteri R28 and exogenous Lactobacillus plantarum AR17-1 and the effects on intestinal inflammation in mice. Food Funct. 2021, 12, 2481–2488.
  4. Galdino, I.K.C.P.D.O.; Oliveira, M.M.; Oliveira, A.T.; da Silva, G.M.; de Oliveira, T.A.; dos Santos, K.M.O.; Egito, A.S.D.; Buriti, F.C.A. Fermentative behavior of native lactobacilli in goat milk and their survival under in vitro simulated gastrointestinal conditions. LWT 2020, 135, 109905.
  5. Flach, J.; van der Waal, M.; Nieuwboer, M.V.D.; Claassen, H.; Larsen, O.F.A. The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters. Crit. Rev. Food Sci. Nutr. 2017, 58, 2570–2584.
  6. Sharma, R.; Mokhtari, S.; Jafari, S.M.; Sharma, S. Barley-based probiotic food mixture: Health effects and future prospects. Crit. Rev. Food Sci. Nutr. 2021, 1–15.
  7. Zhu, W.; Lyu, F.; Naumovski, N.; Ajlouni, S.; Ranadheera, C.S. Functional Efficacy of Probiotic Lactobacillus sanfranciscensis in Apple, Orange and Tomato Juices with Special Reference to Storage Stability and In Vitro Gastrointestinal Survival. Beverages 2020, 6, 13.
  8. De Oliveira, P.M.; de Castro Leite Junior, B.R.; Martins, E.M.F.; Martins, M.L.; Vieira, N.R.; de Barros, F.A.R.; Cristianini, M.; de Almeida Costa, N.; Ramos, A.M. Mango and carrot mixed juice: A new matrix for the vehicle of probiotic lactobacilli. J. Food Sci. Technol. 2020, 58, 98–109.
  9. Gao, H.; Wen, J.-J.; Hu, J.-L.; Nie, Q.-X.; Chen, H.-H.; Nie, S.-P.; Xiong, T.; Xie, M.-Y. Momordica charantia juice with Lactobacillus plantarum fermentation: Chemical composition, antioxidant properties and aroma profile. Food Biosci. 2019, 29, 62–72.
  10. Chen, R.; Chen, W.; Chen, H.; Zhang, G.; Chen, W. Comparative Evaluation of the Antioxidant Capacities, Organic Acids, and Volatiles of Papaya Juices Fermented by Lactobacillus acidophilus and Lactobacillus plantarum. J. Food Qual. 2018, 2018, 1–12.
  11. Zhong, H.; Abdullah; Zhao, M.; Tang, J.; Deng, L.; Feng, F. Probiotics-fermented blueberry juices as potential antidiabetic product: Antioxidant, antimicrobial and antidiabetic potentials. J. Sci. Food Agric. 2021, 101, 4420–4427.
  12. Shikano, A.; Kuda, T.; Shibayama, J.; Toyama, A.; Ishida, Y.; Takahashi, H.; Kimura, B. Effects of Lactobacillus plantarum Uruma-SU4 fermented green loofah on plasma lipid levels and gut microbiome of high-fat diet fed mice. Food Res. Int. 2019, 121, 817–824.
  13. Hu, J.-P.; Zheng, T.-T.; Zeng, B.-F.; Wu, M.-L.; Shi, R.; Zhang, Y.; Chen, L.-J.; Cheng, W.-J.; Liang, P. Effects of Lactobacillus plantarum FZU3013-Fermented Laminaria japonica on Lipid Metabolism and Gut Microbiota in Hyperlipidaemic Rats. Front. Nutr. 2021, 8, 786571.
  14. Tsui, C.-Y.; Yang, C.-Y. Evaluation of Semi-Solid-State Fermentation of Elaeocarpus serratus L. Leaves and Black Soymilk by Lactobacillus plantarum on Bioactive Compounds and Antioxidant Capacity. Foods 2021, 10, 704.
  15. Mirlohi, M.; Babashahi, M.; Ghiasvand, R.; Azadbakht, L.; Mosharaf, L.; Torki-Baghbadorani, S. Effects of probiotic soy milk fermented by lactobacillus plantarum A7 (KC 355240) added with Cuminum Cyminum essential oil on fasting blood glucose levels, serum lipid profile and body weight in diabetic Wistar rats. Int. J. Prev. Med. 2020, 11, 8.
  16. Cao, C.; Wu, R.; Zhu, X.; Li, Y.; Li, M.; An, F.; Wu, J. Ameliorative effect of Lactobacillus plantarum WW-fermented soy extract on rat fatty liver via the PPAR signaling pathway. J. Funct. Foods 2019, 60, 103439.
  17. de la Fuente, B.; Luz, C.; Puchol, C.; Meca, G.; Barba, F.J. Evaluation of fermentation assisted by Lactobacillus brevis POM, and Lactobacillus plantarum (TR-7, TR-71, TR-14) on antioxidant compounds and organic acids of an orange juice-milk based beverage. Food Chem. 2020, 343, 128414.
  18. Mushtaq, M.; Gani, A.; Masoodi, F. Himalayan cheese (Kalari/Kradi) fermented with different probiotic strains: In vitro investigation of nutraceutical properties. LWT 2019, 104, 53–60.
  19. Moreno-Montoro, M.; Olalla-Herrera, M.; Rufián-Henares, J.; Martínez, R.G.; Miralles, B.; Bergillos, T.; Navarro-Alarcón, M.; Jauregi, P. Antioxidant, ACE-inhibitory and antimicrobial activity of fermented goat milk: Activity and physicochemical property relationship of the peptide components. Food Funct. 2017, 8, 2783–2791.
  20. Li, Y.; Wu, J.; Cao, C.; Zhu, X.; Sun, X.; Wu, R. Effects of skim milk fermented with Lactobacillus plantarum WW on the constitutions of rats fed a high-fat diet. J. Dairy Sci. 2020, 103, 5019–5029.
  21. Albano, C.; Morandi, S.; Silvetti, T.; Casiraghi, M.; Manini, F.; Brasca, M. Lactic acid bacteria with cholesterol-lowering properties for dairy applications: In vitro and in situ activity. J. Dairy Sci. 2018, 101, 10807–10818.
  22. Wang, M.; Lei, M.; Samina, N.; Chen, L.; Liu, C.; Yin, T.; Yan, X.; Wu, C.; He, H.; Yi, C. Impact of Lactobacillus plantarum 423 fermentation on the antioxidant activity and flavor properties of rice bran and wheat bran. Food Chem. 2020, 330, 127156.
  23. Wu, H.; Rui, X.; Li, W.; Xiao, Y.; Zhou, J.; Dong, M. Whole-grain oats (Avena sativa L.) as a carrier of lactic acid bacteria and a supplement rich in angiotensin I-converting enzyme inhibitory peptides through solid-state fermentation. Food Funct. 2018, 9, 2270–2281.
  24. Luan, X.; Feng, M.; Sun, J. Effect of Lactobacillus plantarum on antioxidant activity in fermented sausage. Food Res. Int. 2021, 144, 110351.
  25. Hashemi, S.; Raeisi, S.; Zanardi, E.; Paciulli, M.; Chiavaro, E. Antimicrobial and Antioxidant Activities of Fermented Meat Patty with Lactobacillus Strains. Ital. J. Food Sci. 2018, 30, 268–279.
  26. Ayyash, M.; Liu, S.-Q.; Al Mheiri, A.; Aldhaheri, M.; Raeisi, B.; Al-Nabulsi, A.; Osaili, T.; Olaimat, A. In vitro investigation of health-promoting benefits of fermented camel sausage by novel probiotic Lactobacillus plantarum: A comparative study with beef sausages. LWT 2018, 99, 346–354.
  27. Kong, Y.-W.; Feng, M.-Q.; Sun, J. Effects of Lactobacillus plantarum CD101 and Staphylococcus simulans NJ201 on proteolytic changes and bioactivities (antioxidant and antihypertensive activities) in fermented pork sausage. LWT 2020, 133, 109985.
  28. Wu, Y.; Li, S.; Tao, Y.; Li, D.; Han, Y.; Show, P.L.; Wen, G.; Zhou, J. Fermentation of blueberry and blackberry juices using Lactobacillus plantarum, Streptococcus thermophilus and Bifidobacterium bifidum: Growth of probiotics, metabolism of phenolics, antioxidant capacity in vitro and sensory evaluation. Food Chem. 2021, 348, 129083.
  29. Zhang, X.; Duan, W.; Zou, J.; Zhou, H.; Liu, C.; Yang, H. Flavor and antioxidant activity improvement of carrot juice by fermentation with Lactobacillus plantarum WZ-01. J. Food Meas. Charact. 2019, 13, 3366–3375.
  30. Bin Jeon, Y.; Lee, J.; Chang, H.C. Characterization of juice fermented with Lactobacillus plantarum EM and its cholesterol-lowering effects on rats fed a high-fat and high-cholesterol diet. Food Sci. Nutr. 2019, 7, 3622–3634.
  31. Singh, B.P.; Vij, S. Growth and bioactive peptides production potential of Lactobacillus plantarum strain C2 in soy milk: A LC-MS/MS based revelation for peptides biofunctionality. LWT 2017, 86, 293–301.
  32. Huang, L.; Feng, M.; Sun, J. Angiotensin-converting enzyme (ACE) inhibitory peptides from fermented sausages inoculated with Lactobacillus plantarum CD101 and Staphylococcus simulans NJ201. Int. J. Food Sci. Technol. 2022, 57, 4985–4997.
  33. de Oliveira, S.D.; Araújo, C.M.; Borges, G.D.S.C.; Lima, M.D.S.; Viera, V.B.; Garcia, E.F.; de Souza, E.L.; de Oliveira, M.E.G. Improvement in physicochemical characteristics, bioactive compounds and antioxidant activity of acerola (Malpighia emarginata D.C.) and guava (Psidium guajava L.) fruit by-products fermented with potentially probiotic lactobacilli. LWT 2020, 134, 110200.
  34. Zhang, Z.-P.; Ma, J.; He, Y.-Y.; Lu, J.; Ren, D.-F. Antioxidant and hypoglycemic effects of Diospyros lotus fruit fermented with Microbacterium flavum and Lactobacillus plantarum. J. Biosci. Bioeng. 2018, 125, 682–687.
  35. Ayyash, M.; Olaimat, A.; Al-Nabulsi, A.; Liu, S.-Q. Bioactive Properties of Novel Probiotic Lactococcus lactis Fermented Camel Sausages: Cytotoxicity, Angiotensin Converting Enzyme Inhibition, Antioxidant Capacity, and Antidiabetic Activity. Korean J. Food Sci. Anim. Resour. 2020, 40, 155–171.
  36. Hashemi, S.M.B.; Gholamhosseinpour, A. Fermentation of table cream by Lactobacillus plantarum strains: Effect on fungal growth, aflatoxin M1 and ochratoxin A. Int. J. Food Sci. Technol. 2018, 54, 347–353.
  37. Dan, T.; Chen, H.; Li, T.; Tian, J.; Ren, W.; Zhang, H.; Sun, T. Influence of Lactobacillus plantarum P-8 on Fermented Milk Flavor and Storage Stability. Front. Microbiol. 2019, 9, 3133.
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