In tThis work, the phases in the Mg-Ti-O system are studied using the 1:1 formulation of MgO:TiO2 mixing synthetic brucite of Mexican origin with high purity TiO2 microparticles and with a heat treatment at 960°C for 1 h. The raw materials and formule X-ray stimulation photospectrometry technique known as XPS is applied to determine chemical bond characteristics of organic and inorganic substances. On the other hand, the processes of chemical substance formation are characterizcan be energetically activated by XPS and DRX techniques. The results demonstrate the presence of different oxidation states in titania and the formation of differentvarious mechanisms, one of them being thermal activation. Magnesium oxide (magnesia, MgO) and titanium oxides in the Mg-Ti-O system when mixed and calcined at 960°C; additionally, the formation of vacancies in the crystal lattice d (titania, TiO2) are substances that, due to their chemical and energetic nature, can chemically react to form other chemical compounds when subjected to relatively high temperatures. During the transformation from hexagonal brucite to magnesia with a cubic structure centered onsintering of MgO it is feasible to use some additives such as TiO2 to improve some properties, but during the process it is possible the faces is estimated. With the results, its thermal behavior is noticedormation of substances that limit its final application at high temperature. This review focuses on the relatively high-temperature synthesis and characterization of compounds based on the MgO-TiO2 phase diagramMgO:TiO2 in a 50:50 wt% ratio, using the XPS technique and supported by XRD.