Calmodulin-Connexin in Gap Junction Channel Regulation-Calmodulin-Cork Gating Model: Comparison
Please note this is a comparison between Version 1 by Camillo Peracchia and Version 6 by Bruce Ren.

In the past four decades numerous findings have indicated that gap junction channel gating is mediated by intracellular calcium concentrations ([Ca2+i]) in the high nanomolar range via calmodulin (CaM). We believe that CaM directly closes the channel by a cork-like gating mechanism.

  • connexins
  • innexins
  • channel gating
  • calcium
  • calmodulin
  • cell communication
  • cell-to-cell channels
  • cell coupling
  • cell uncoupling
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