Polymeric Nanoparticles for Drug Delivery: Comparison
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Please note this is a comparison between Version 1 by Manuel Merinero and Version 3 by Catherine Yang.

The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led to an increasing interest in the development and optimization of drug-delivery systems. Polymeric nanoparticles stand out as a key tool to improve drug bioavailability or specific delivery at the site of action. The versatility of polymers makes them potentially ideal for fulfilling the requirements of each particular drug-delivery system. In this review, a summary of the state-of-the-art panorama of polymeric nanoparticles as drug-delivery systems has been conducted, focusing mainly on those applications in which the corresponding disease involves an important morbidity, a considerable reduction in the life quality of patients—or even a high mortality. A revision of the use of polymeric nanoparticles for ocular drug delivery, for cancer diagnosis and treatment, as well as nutraceutical delivery, was carried out, and a short discussion about future prospects of these systems is included.

  • nanoparticles
  • nanocarriers
  • polymeric materials
  • drug-delivery systems
  • ocular delivery
  • cancer diagnosis
  • cancer drug-delivery systems
  • nutraceuticals
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