Spin-Dependent Phenomena in Semiconductor Micro/Nanoparticles: Comparison
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Please note this is a comparison between Version 1 by Vladimir Fomin and Version 3 by Vladimir Fomin.

- Spin-dependent phenomena in semiconductors are analyzed starting from a theory of the dynamic nuclear polarization via numerous insightful findings in the realm of characterization and control through the nuclear spin polarization in nanoparticles and their aggregates into microparticles as potential contrast agents for magnetic resonance imaging (MRI) applications. 

- Electron spin-dependent process of the photosensitized generation of singlet oxygen in porous silicon (Si) for photodynamic therapy application and design of Si-based nanoparticles with electron spin centers for MRI contrasting for cancer theranostics are discussed.

 

The present overview of spin-dependent phenomena in nonmagnetic semiconductor microparticles (MPs) and nanoparticles (NPs) with interacting nuclear and electron spins is aimed at covering a gap between the basic properties of spin behavior in solid-state systems and a tremendous growth of the experimental results on biomedical applications of those particles. We represent modern achievements of spin-dependent phenomena in the bulk semiconductors from the theory of optical spin orientation under indirect optical injection of carriers and spins in the bulk crystalline silicon (c-Si)—via numerous insightful findings in the realm of characterization and control through the spin polarization—to the design and verification of nuclear spin hyperpolarization in semiconductor MPs and NPs for magnetic resonance imaging (MRI) diagnostics. The electron spin-dependent phenomena in Si-based nanostructures include the photosensitized generation of singlet oxygen in porous Si and design of Si NPs with unpaired electron spins as prospective contrast agents in MRI. The experimental results are analyzed by considering both the quantum mechanical approach and several phenomenological models for the spin behavior in semiconductor/molecular systems. Advancements and perspectives of the biomedical applications of spin-dependent properties of Si NPs for diagnostics and therapy of cancer are discussed.

  • micro-and nanoparticles
  • optically induced dynamic nuclear polarization
  • optical spin orientation
  • nuclear spin hyperpolarization
  • silicon
  • photosensitized generation
  • singlet oxygen
  • magnetic resonance imaging
  • diagnostics and therapy of cancer
  • Si micro-and nanoparticles
  • photosensitized generation of singlet oxygen
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References

  1. Fomin, V.M.; Timoshenko, V.Yu. Spin-Dependent Phenomena in Semiconductor Micro- and Nanoparticles—From Fundamentals to Applications, Appl. Sci. 2020, 10, 4992, doi:10.3390/app10144992Luu, Q.S.; Kim, J.; Jo, D.; Jeong, J.; Lee, Y. Applications and perspective of silicon particles in hyperpolarized 29Si magnetic resonance imaging. Appl. Spectrosc. Rev. 2020, 55, 476-490, doi:10.1080/05704928.2019.1676255.
  2. Abragam, A.; Goldman, M. Principles of dynamic nuclear polarisation. Rep. Prog. Phys. 1978, 41, 395–467, doi:10.1088/0034-4885/41/3/002.Timoshenko, V.Y.Porous Silicon in Photodynamic and Photothermal Therapy. In: Handbook of Porous Silicon, 2nd ed.; Canham, L., Ed.; Springer: Berlin-Heidelberg, Germany, 2018; pp. 1461–1469, doi:10.1007/978-3-319-71381-6_93.
  3. Kwiatkowski, G.; Polyhach, Y.; Jähnig, F.; Shiroka, T.; Starsich, F.H.L.; Ernst, M.; Kozerke, S. Exploiting Endogenous Surface Defects for Dynamic Nuclear Polarization of Silicon Micro- and Nanoparticles. J. Phys. Chem. C 2018, 122, 25668–25680, doi:10.1021/acs.jpcc.8b08926.Kabashin, A.V.; Timoshenko, V.Y. What theranostic applications could ultrapure laser-synthesized Si nanoparticles have in cancer? Nanomedicine 2016, 11, 2247–2250, doi:10.2217/nnm-2016-0228.
  4. Lampel, G. Nuclear Dynamic Polarization by Optical Electronic Saturation and Optical Pumping in Semiconductors. Phys. Rev. Lett. 1968, 20, 491–493, doi:10.1103/physrevlett.20.491.Zinovieva, A.F.; Nikiforov, A.I.; Timofeev, V.A.; Nenashev, A.V.; Dvurechenskii, A.V.; Kulik, L.V. Electron localization in Ge/Si heterostructures with double quantum dots detected by an electron spin resonance method. Phys. Rev. B 2013, 88, 235308, 1-8, doi:10.1103/physrevb.88.235308.
  5. Overhauser, A.W. Polarization of Nuclei in Metals. Phys. Rev. 1953, 92, 411–415, doi:10.1103/physrev.92.411.Lipps, F.; Pezzoli, F.; Stoffel, M.; Deneke, C.; Thomas, J.; Rastelli, A.; Kataev, V.; Schmidt, O.G.; Büchner, B. Electron spin resonance study of Si/SiGe quantum dots. Phys. Rev. B 2010, 81, 125312, 1-9, doi:10.1103/physrevb.81.125312.
  6. Dyakonov, M.I.; Perel, V.I. Theory of Optical Spin Orientation of Electrons and Nuclei in Semiconductors. In: Optical Orientation; Meier, F., Zakharchenya, B.P., Eds.; Elsevier: Amsterdam, The Netherlands, 1984, doi:10.1016/B978-0-444-86741-4.50007-X.Giorgioni, A.; Paleari, S.; Cecchi, S.; Vitiello, E.; Grilli, E.; Isella, G.; Jantsch, W.; Fanciulli, M.; Pezzoli, F. Strong confinement-induced engineering of the g factor and lifetime of conduction electron spins in Ge quantum wells. Nat. Commun. 2016, 7, 13886, 1–11. Available online: https://www.nature.com/articles/ncomms13886 (accessed on July 17, 2020)..
  7. Abragam, A. The Principles of Nuclear Magnetism; Oxford University Press: Oxford, UK, 1961.Khaetskii, A.V.; Nazarov, Y.V. Spin-flip transitions between Zeeman sublevels in semiconductor quantum dots. Phys. Rev. B 2001, 64, 125316, 16, doi:10.1103/physrevb.64.125316.
  8. Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Optical orientation of 29Si nuclei in n-type silicon and its dependence on the pumping light intensity. Sov. Phys. JETP 1976, 44, 500–504Alcalde, A.M.; Marques, G.E. Electron spin-phonon relaxation in quantum dots. Braz. J. Phys. 2004, 34, 705707. Available online: http://www.sbfisica.org.br/bjp/files/v34_705.pdf (accessed on July 17, 2020).
  9. Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Influence of the depth of location of donor levels on the degree of optical orientation of 29Si nuclei in silicon. Sov. Phys. JETP Lett. 1976, 24, 366368.Abragam, A.; Goldman, M. Principles of dynamic nuclear polarisation. Rep. Prog. Phys. 1978, 41, 395–467, doi:10.1088/0034-4885/41/3/002.
  10. Ekimov, A.I.; Safarov, V.I. Optical detection of dynamic polarization of nuclei in semiconductors. JETP Lett. 1972, 15, 179181Kwiatkowski, G.; Polyhach, Y.; Jähnig, F.; Shiroka, T.; Starsich, F.H.L.; Ernst, M.; Kozerke, S. Exploiting Endogenous Surface Defects for Dynamic Nuclear Polarization of Silicon Micro- and Nanoparticles. J. Phys. Chem. C 2018, 122, 25668–25680, doi:10.1021/acs.jpcc.8b08926.
  11. Tycko, R. Optical pumping in indium phosphide: 31P NMR measurements and potential for signal enhancement in biological solid state NMR. Solid State Nucl. Magn. Reson. 1998, 11, 1–9.Aptekar, J.W.; Cassidy, M.C.; Johnson, A.C.; Barton, R.A.; Lee, M.; Ogier, A.C.; Vo, C.; Anahtar, M.N.; Ren, Y.; Bhatia, S.N.; et al. Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents. ACS Nano 2009, 3, 4003–4008, doi:10.1021/nn900996p.
  12. Pietraß, T.; Tomaselli, M. Optically pumped NMR in CdS single crystals. Phys. Rev. B 1999, 59, 1986–1989, doi:10.1103/physrevb.59.1986.Abragam, A. The Principles of Nuclear Magnetism; Oxford University Press: Oxford, UK, 1961.
  13. Zucchetti, C.; Bottegoni, F.; Isella, G.; Finazzi, M.; Rortais, F.; Vergnaud, C.; Widiez, J.; Jamet, M.; Ciccacci, F. Spin-to-charge conversion for hot photoexcited electrons in germanium. Phys. Rev. B 2018, 97, 17, doi:10.1103/PhysRevB.97.125203.Jansen, R. Silicon spintronics. Nat. Mater. 2012, 11, 400–408, doi:10.1038/nmat3293.
  14. De Cesari, S.; Balocchi, A.; Vitiello, E.; Jahandar, P.; Grilli, E.; Amand, T.; Marie, X.; Myronov, M.; Pezzoli, F. Spin-coherent dynamics and carrier lifetime in strained Ge1−xSnx semiconductors on silicon. Phys. Rev. B 2019, 99, 1–9, doi:10.1103/physrevb.99.035202.Lampel, G. Nuclear Dynamic Polarization by Optical Electronic Saturation and Optical Pumping in Semiconductors. Phys. Rev. Lett. 1968, 20, 491–493, doi:10.1103/physrevlett.20.491.
  15. Fujiwara, T.; Ramamoorthy, A. How far can the sensitivity of NMR be increased? Annu. Rep. NMR Spectrosc. 2006, 58, 155–175, doi:10-1016/S0066-4013(05)58003-7.Lampel, G. Relaxation Nucléaire dans le Silicium à 77°K et Polarisation Dynamique par Pompage Optique. Ph.D. Thesis, Faculte des Sciences de l'Université de Paris a Orsay pour obtenir le grade de Docteur-ès-Sciences Physiques, Université de Paris, Paris, France, 1968.
  16. Atkins, T.M.; Cassidy, M.C.; Lee, M.; Ganguly, S.; Marcus, C.M.; Kauzlarich, S.M. Synthesis of Long T1 Silicon Nanoparticles for Hyperpolarized 29Si Magnetic Resonance Imaging. ACS Nano 2013, 7, 1609–1617, doi:10.1021/nn305462y.Overhauser, A.W. Polarization of Nuclei in Metals. Phys. Rev. 1953, 92, 411–415, doi:10.1103/physrev.92.411.
  17. Aptekar, J.W.; Cassidy, M.C.; Johnson, A.C.; Barton, R.A.; Lee, M.; Ogier, A.C.; Vo, C.; Anahtar, M.N.; Ren, Y.; Bhatia, S.N.; et al. Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents. ACS Nano 2009, 3, 4003–4008, doi:10.1021/nn900996p.Kittel, C. Introduction to Solid State Physics; John Wiley & Sons: New York, NY, USA, 1996.
  18. Shulman, R.G.; Wyluda, B.J. Nuclear magnetic resonance of 29Si in n- and p-type silicon. Phys. Rev. 1956, 103, 11271129, doi:10.1103/PhysRev.103.1127.
  19. Casabianca, L.B.; Shames, A.I.; Panich, A.M.; Shenderova, O.; Frydman, L. Factors Affecting DNP NMR in Polycrystalline Diamond Samples. J. Phys. Chem. C 2011, 115, 19041–19048, doi:10.1021/jp206167j.Bloembergen, N. Nuclear magnetic relaxation in semiconductors. Physica 1954, 20, 1130–1133, doi:10.1016/s0031-8914(54)80253-9.
  20. Dementyev, A.E.; Cory, D.G.; Ramanathan, C. Dynamic Nuclear Polarization in Silicon Microparticles. Phys. Rev. Lett. 2008, 100, 1–4, doi:10.1103/physrevlett.100.127601.Lee, M.; Cassidy, M.C.; Ramanathan, C.; Marcus, C.M. Decay of nuclear hyperpolarization in silicon microparticles. Phys. Rev. B 2011, 84, 035304, doi:10.1103/physrevb.84.035304.
  21. Cassidy, M.C.; Chan, H.R.; Ross, B.D.; Bhattacharya, P.K.; Marcus, C.M. In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat. Nanotechnol. 2013, 8, 363–368, doi:10.1038/nnano.2013.65.Dyakonov, M.I.; Perel, V.I. Theory of Optical Spin Orientation of Electrons and Nuclei in Semiconductors. In: Optical Orientation; Meier, F., Zakharchenya, B.P., Eds.; Elsevier: Amsterdam, The Netherlands, 1984, doi:10.1016/B978-0-444-86741-4.50007-X.
  22. Lee, M.; Cassidy, M.C.; Ramanathan, C.; Marcus, C.M. Decay of nuclear hyperpolarization in silicon microparticles. Phys. Rev. B 2011, 84, 035304, doi:10.1103/physrevb.84.035304.Chekhovich, E.A.; Glazov, M.M.; Krysa, A.; Hopkinson, M.; Senellart, P.; Lemaître, A.; Skolnick, M.S.; Tartakovskii, A.I. Element-sensitive measurement of the hole–nuclear spin interaction in quantum dots. Nat. Phys. 2012, 9, 74–78, doi:10.1038/nphys2514.
  23. Kwiatkowski, G.; Jähnig, F.; Steinhauser, J.; Wespi, P.; Ernst, M.; Kozerke, S. Nanometer size silicon particles for hyperpolarized MRI. Sci. Rep. 2017, 7, 1–6; https://www.nature.com/articles/s41598-017-08709-0.Overhauser, A.W. Paramagnetic Relaxation in Metals. Phys. Rev. 1953, 89, 689–700, doi:10.1103/physrev.89.689.
  24. Kovalev, D.; Gross, E.; Künzner, N.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Resonant Electronic Energy Transfer from Excitons Confined in Silicon Nanocrystals to Oxygen Molecules. Phys. Rev. Lett. 2002, 89, 1–4, doi:10.1103/physrevlett.89.137401.Li, P.; Dery, H. Theory of Spin-Dependent Phonon-Assisted Optical Transitions in Silicon. Phys. Rev. Lett. 2010, 105, 1–4, doi:10.1103/physrevlett.105.037204.
  25. Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Spectrally resolved electronic energy transfer from silicon nanocrystals to molecular oxygen mediated by direct electron exchange. Phys. Rev. B 2003, 68, 1–11, doi:10.1103/physrevb.68.115405.Cassidy, M.C.; Chan, H.R.; Ross, B.D.; Bhattacharya, P.K.; Marcus, C.M. In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat. Nanotechnol. 2013, 8, 363–368, doi:10.1038/nnano.2013.65.
  26. Fujii, M.; Kovalev, D.; Goller, B.D.; Minobe, S.; Hayashi, S.; Timoshenko, V.Y. Time-resolved photoluminescence studies of the energy transfer from excitons confined in Si nanocrystals to oxygen molecules. Phys. Rev. B 2005, 72, 165321, doi:10.1103/physrevb.72.165321.Atkins, T.M.; Cassidy, M.C.; Lee, M.; Ganguly, S.; Marcus, C.M.; Kauzlarich, S.M. Synthesis of Long T1 Silicon Nanoparticles for Hyperpolarized 29Si Magnetic Resonance Imaging. ACS Nano 2013, 7, 1609–1617, doi:10.1021/nn305462y.
  27. Timoshenko, V.Y.; Kudryavtsev, A.A.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Belogorokhov, I.A.; Kovalev, D.; Kashkarov, P.K. Silicon nanocrystals as photosensitizers of active oxygen for biomedical applications. JETP Lett. 2006, 83, 423–426, doi:10.1134/s0021364006090128.Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Optical orientation of Si29 nuclei in n-type silicon and its dependence on the pumping light intensity. Sov. Phys. JETP 1976, 44, 500–504
  28. Timoshenko, V.Y.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Gongalsky, M.; Efimova, A.I.; Konstantinova, E.A.; Bazylenko, T.Y.; Kashkarov, P.K.; Kudriavtsev, A.A. Silicon nanocrystals as efficient photosensitizer of singlet oxygen for biomedical applications. SPIE Proc. 2007, 6606, 66061E, doi:10.1117/12.729523.Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Influence of the depth of location of donor levels on the degree of optical orientation of 29Si nuclei in silicon. Sov. Phys. JETP Lett. 1976, 24, 366368.
  29. Xiao, L.; Gu, L.; Howell, S.B.; Sailor, M. Porous Silicon Nanoparticle Photosensitizers for Singlet Oxygen and Their Phototoxicity against Cancer Cells. ACS Nano 2011, 5, 3651–3659, doi:10.1021/nn1035262.Verhulst, A.S.; Rau, I.G.; Yamamoto, Y.; Itoh, K.M. Optical pumping of Si29 nuclear spins in bulk silicon at high magnetic field and liquid helium temperature. Phys. Rev. B 2005, 71, 1–10, doi:10.1103/physrevb.71.235206.
  30. Osminkina, L.; Tamarov, K.P.; Sviridov, A.P.; Galkin, R.A.; Gongalsky, M.B.; Solovyev, V.V.; Kudryavtsev, A.A.; Timoshenko, V.Y. Photoluminescent biocompatible silicon nanoparticles for cancer theranostic applications. J. Biophotonics 2012, 5, 529–535, doi:10.1002/jbio.201100112.Ekimov, A.I.; Safarov, V.I. Optical detection of dynamic polarization of nuclei in semiconductors. JETP Lett. 1972, 15, 179-181.
  31. Timoshenko, V.Y. Porous Silicon in Photodynamic and Photothermal Therapy. In: Handbook of Porous Silicon, 2nd ed.; Canham, L., Ed.; Springer: BerlinHeidelberg, Germany, 2018; pp. 1461–1469, doi:10.1007/978-3-319-71381-6_93.Tycko, R. Optical pumping in indium phosphide: 31P NMR measurements and potential for signal enhancement in biological solid state NMR. Solid State Nucl. Magn. Reson. 1998, 11, 1–9.
  32. Kabashin, A.V.; Timoshenko, V.Y. What theranostic applications could ultrapure laser-synthesized Si nanoparticles have in cancer? Nanomedicine 2016, 11, 2247–2250, doi:10.2217/nnm-2016-0228.Pietraß, T.; Tomaselli, M. Optically pumped NMR in CdS single crystals. Phys. Rev. B 1999, 59, 1986–1989, doi:10.1103/physrevb.59.1986.
  33. Gongalsky, M.B.; Kargina, Y.V.; Osminkina, L.; Perepukhov, A.M.; Gulyaev, M.; Vasiliev, A.; Pirogov, Y.A.; Maximychev, A.V.; Timoshenko, V.Y. Porous silicon nanoparticles as biocompatible contrast agents for magnetic resonance imaging. Appl. Phys. Lett. 2015, 107, 233702, doi:10.1063/1.4937731.Cheng, J.L.; Rioux, J.; Fabian, J.; Sipe, J.E. Theory of optical spin orientation in silicon. Phys. Rev. B 2011, 83, 1–15, doi:10.1103/physrevb.83.165211.
  34. Kargina, Y.V.; Gongalsky, M.B.; Perepukhov, A.M.; Gippius, A.A.; Minnekhanov, A.A.; Zvereva, E.A.; Maximychev, A.V.; Timoshenko, V.Y. Investigation of proton spin relaxation in water with dispersed silicon nanoparticles for potential magnetic resonance imaging applications. J. Appl. Phys. 2018, 123, 1–6, doi:10.1063/1.5006846.Cheng, J.L.; Rioux, J.; Sipe, J.E. Two-photon indirect optical injection and two-color coherent control in bulk silicon. Phys. Rev. B 2011, 84, 1–13, doi:10.1103/physrevb.84.235204.
  35. Cullis, A.G.; Canham, L.T.; Calcott, P.D.J. The structural and luminescence properties of porous silicon. J. Appl. Phys. 1997, 82, 909–965, doi:10.1063/1.366536.Guite, C.; Venkataraman, V. Measurement of Electron Spin Lifetime and Optical Orientation Efficiency in Germanium Using Electrical Detection of Radio Frequency Modulated Spin Polarization. Phys. Rev. Lett. 2011, 107, 1–4, doi:10.1103/physrevlett.107.166603.
  36. Rohrer, M.; Bauer, H.; Mintorovitch, J.; Requardt, M.; Weinmann, H.-J. Comparison of Magnetic Properties of MRI Contrast Media Solutions at Different Magnetic Field Strengths. Investig. Radiol. 2005, 40, 715–724, doi:10.1097/01.rli.0000184756.66360.d3.Pezzoli, F.; Bottegoni, F.; Trivedi, D.; Ciccacci, F.; Giorgioni, A.; Li, P.; Cecchi, S.; Grilli, E.; Song, Y.; Guzzi, M.; et al. Optical Spin Injection and Spin Lifetime in Ge Heterostructures. Phys. Rev. Lett. 2012, 108, 1–5, doi:10.1103/physrevlett.108.156603.
  37. Araki, K.; Uchiyama, M.K.; Toma, S.; Rodrigues, S.F.; Shimada, A.L.B.; Loiola, R.A.; Rodríguez, H.J.C.; Oliveira, P.V.; Luz, M.S.; Rabbani, S.R.; et al. Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool. Int. J. Nanomed. 2015, 10, 4731–4746, doi:10.2147/IJN.S83150.Giorgioni, A.; Vitiello, E.; Grilli, E.; Guzzi, M.; Pezzoli, F. Valley-dependent spin polarization and long-lived electron spins in germanium. Appl. Phys. Lett. 2014, 105, 152404, doi:10.1063/1.4898078.
  38. Kargina, Y.V.; Perepukhov, A.M.; Kharin, A.Y.; Zvereva, E.A.; Koshelev, A.V.; Zinovyev, S.V.; Maximychev, A.V.; Alykova, A.F.; Sharonova, N.V.; Zubov, V.P.; et al. Silicon Nanoparticles Prepared by Plasma‐Assisted Ablative Synthesis: Physical Properties and Potential Biomedical Applications. Phys. Status Solidi A 2019, 216, 1800897, doi:10.1002/pssa.201800897.Li, P.; Trivedi, D.; Dery, H. Spin-dependent optical properties in strained silicon and germanium. Phys. Rev. B 2013, 87, 1–15, doi:10.1103/physrevb.87.115203.
  39. Kargina, Y.V.; Zinovyev, S.V.; Perepukhov, A.M.; Suslova, E.V.; Ischenko, A.A.; Timoshenko, V.Y. Silicon nanoparticles with iron impurities for multifunctional applications. Funct. Mater. Lett. 2020, 13, 2040007, doi:10.1142/s179360472040007x.Liu, Z.; Nestoklon, M.O.; Cheng, J.L.; Ivchenko, E.L.; Wu, M.W. Spin-dependent intravalley and intervalley electron–phonon scatterings in germanium. Phys. Solid State 2013, 55, 1619–1734, doi:10.1134/S1063783413080167.
  40. Bouchoucha, M.; Van Heeswijk, R.B.; Gossuin, Y.; Kleitz, F.; Fortin, M.-A. Fluorinated Mesoporous Silica Nanoparticles for Binuclear Probes in 1H and 19F Magnetic Resonance Imaging. Langmuir 2017, 33, 10531–10542, doi:10.1021/acs.langmuir.7b01792.Sircar, N.; Bougeard, D. Experimental investigation of the optical spin-selection rules in bulk Si and Ge/Si quantum dots. Phys. Rev. B 2014, 89, 1–5, doi:10.1103/physrevb.89.041301.
  41. Akimoto, I.; Naka, N. Two optical routes of cold carrier injection in silicon revealed by time-resolved excitation spectroscopy. Appl. Phys. Express 2017, 10, 1-4, doi:10.7567/APEX.10.061301.
  42. Bottegoni, F.; Zucchetti, C.; Ciccacci, F.; Finazzi, M.; Isella, G. Optical generation of pure spin currents at the indirect gap of bulk Si. Appl. Phys. Lett. 2017, 110, 1–5, doi:10.1063/1.4974820.
  43. Cushing, S.K.; Zürch, M.; Kraus, P.M.; Carneiro, L.M.; Lee, A.; Chang, H.-T.; Kaplan, C.J.; Leone, S.R. Hot phonon and carrier relaxation in Si(100) determined by transient extreme ultraviolet spectroscopy. Struct. Dyn. 2018, 5, 1–20, doi:10.1063/1.5038015.
  44. Zucchetti, C.; Bottegoni, F.; Isella, G.; Finazzi, M.; Rortais, F.; Vergnaud, C.; Widiez, J.; Jamet, M.; Ciccacci, F. Spin-to-charge conversion for hot photoexcited electrons in germanium. Phys. Rev. B 2018, 97, 1-7, doi:10.1103/PhysRevB.97.125203.
  45. De Cesari, S.; Balocchi, A.; Vitiello, E.; Jahandar, P.; Grilli, E.; Amand, T.; Marie, X.; Myronov, M.; Pezzoli, F. Spin-coherent dynamics and carrier lifetime in strained Ge1−xSnx semiconductors on silicon. Phys. Rev. B 2019, 99, 1–9, doi:10.1103/physrevb.99.035202.
  46. Ardenkjaer-Larsen, J.H.; Fridlund, B.; Gram, A.; Hansson, G.; Lennart Hansson, L.; Lerche, M.H.; Servin, R.; Thaning, M.; Golman, K. Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc. Natl. Acad. Sci. USA 2003, 100, 10158–10163, doi:10.1073/pnas.1733835100.
  47. Fujiwara, T.; Ramamoorthy, A. 2006. How far can the sensitivity of NMR be increased? Annu. Rep. NMR Spectrosc. 2006, 58, 155–175, doi:10-1016/S0066-4013(05)58003-7.
  48. Van Kesteren, H.W.; Wenckebach, W.T.; Schmidt, J. Production of High, Long-Lasting, Dynamic Proton Polarization by Way of Photoexcited Triplet States. Phys. Rev. Lett. 1985, 55, 1642–1644, doi:10.1103/physrevlett.55.1642.
  49. Lelli, M.; Gajan, D.; Lesage, A.; Caporini, M.A.; Vitzthum, V.; Miéville, P.; Héroguel, F.; Rascón, F.; Roussey, A.; Thieuleux, C.; et al. Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface-Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization. J. Am. Chem. Soc. 2011, 133, 2104–2107, doi:10.1021/ja110791d.
  50. Casabianca, L.B.; Shames, A.I.; Panich, A.M.; Shenderova, O.; Frydman, L. Factors Affecting DNP NMR in Polycrystalline Diamond Samples. J. Phys. Chem. C 2011, 115, 19041–19048, doi:10.1021/jp206167j.
  51. Dementyev, A.E.; Cory, D.G.; Ramanathan, C. Dynamic Nuclear Polarization in Silicon Microparticles. Phys. Rev. Lett. 2008, 100, 1–4, doi:10.1103/physrevlett.100.127601.
  52. Kwiatkowski, G.; Jähnig, F.; Steinhauser, J.; Wespi, P.; Ernst, M.; Kozerke, S. Nanometer size silicon particles for hyperpolarized MRI. Sci. Rep. 2017, 7, 1–6. Available online: https://www.nature.com/articles/s41598-017-08709-0 (accessed on July 17, 2020).
  53. Whiting, N.; Hu, J.; Shah, J.V.; Cassidy, M.C.; Cressman, E.; Millward, S.W.; Menter, D.G.; Marcus, C.M.; Bhattacharya, P.K. Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles. Sci. Rep. 2015, 5, 1–8, doi:10.1038/srep12842.
  54. Whiting, N.; Hu, J.; Zacharias, N.M.; Lokesh, G.L.; Volk, D.E.; Menter, D.G.; Rupaimoole, R.; Previs, R.; Sood, A.K.; Bhattacharya, P. Developing hyperpolarized silicon particles for In Vivo MRI targeting of ovarian cancer. J. Med. Imaging 2016, 3, 1–9, doi:10.1117/1.JMI.3.3.036001.
  55. Seo, H.; Choi, I.; Whiting, N.; Hu, J.; Luu, Q.S.; Pudakalakatti, S.; McCowan, C.; Kim, Y.; Zacharias, N.; Lee, Y.; et al. Hyperpolarized Porous Silicon Nanoparticles: Potential Theragnostic Material for 29Si Magnetic Resonance Imaging. ChemPhysChem 2018, 19, 2143–2147, doi:10.1002/cphc.201800461.
  56. Hu, J.; Whiting, N.; Bhattacharya, P.K. Hyperpolarization of Silicon Nanoparticles with TEMPO Radicals. J. Phys. Chem. C 2018, 122, 10575–10581, doi:10.1021/acs.jpcc.8b00911.
  57. Sanders, G.D.; Chang, Y.-C. Theory of optical properties of quantum wires in porous silicon. Phys. Rev. B 1992, 45, 9202–9213, doi:10.1103/physrevb.45.9202.
  58. Delley, B.; Steigmeier, E.F. Size dependence of band gaps in silicon nanostructures. Appl. Phys. Lett. 1995, 67, 2370–2372, doi:10.1063/1.114348.
  59. John, G.J.; Singh, V.A. Porous silicon: Theoretical studies. Phys. Rep. 1995, 263, 93–151, doi:10.1016/0370-1573(95)00052-4.
  60. Calcott, P.D.J.; Nash, K.J.; Canham, L.T.; Kane, M.J.; Brumhead, D. Identification of radiative transitions in highly porous silicon. J. Phys. Condens. Matter 1993, 5, L91–L98, doi:10.1088/0953-8984/5/7/003.
  61. Kovalev, D.; Heckler, H.; Polisski, G.; Koch, F. Optical Properties of Si Nanocrystals. Phys. Status Solidi B 1999, 215, 871–932, doi:10.1002/(sici)1521-3951(199910)215:23.0.co;2-9.
  62. Bisi, O.; Ossicini, S.; Pavesi, L. Porous silicon: A quantum sponge structure for silicon based optoelectronics. Surf. Sci. Rep. 2000, 38, 1–126, doi:10.1016/s0167-5729(99)00012-6.
  63. Moser, J.G. Photodynamic Tumor Therapy: 2nd and 3rd Generation Photosensitizers; Harwood Academic Publushers: Amsterdam, The Netherlands, 1998.
  64. Kovalev, D.; Gross, E.; Künzner, N.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Resonant Electronic Energy Transfer from Excitons Confined in Silicon Nanocrystals to Oxygen Molecules. Phys. Rev. Lett. 2002, 89, 1–4, doi:10.1103/physrevlett.89.137401.
  65. Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Spectrally resolved electronic energy transfer from silicon nanocrystals to molecular oxygen mediated by direct electron exchange. Phys. Rev. B 2003, 68, 1–11, doi:10.1103/physrevb.68.115405.
  66. Turro, N.J. Modern Molecular Photochemistry; University Science Books: Mill Valley, CA, USA, 1991.
  67. Kearns, D.R. Physical and chemical properties of singlet molecular oxygen. Chem. Rev. 1971, 71, 395–427, doi:10.1021/cr60272a004.
  68. Arnold, S.J.; Kubo, M.; Ogryzlo, E.A. Relaxation and Reactivity of Singlet Oxygen. Adv. Chem. 1968, 77, 133–142, doi:10.1021/ba-1968-0077.ch070.
  69. Krasnovsky, A.A.; Kubo, M.; Ogryzlo, A. Singlet molecular oxygen in photobiochemical systems: IR phosphorescence studies, Membr. Cell Biol. 1998, 12, 665–690.
  70. Fujii, M.; Minobe, S.; Usui, M.; Hayashi, Sh.; Gross, E.; Diener, J., Kovalev, D. Singlet oxygen formation by porous Si in solution. Phys. Rev. B 2004, 70, 085311, doi:1103/PhysRevB.70.085311.
  71. Kovalev, D.; Fujii, M. Silicon Nanocrystals: Photosensitizers for Oxygen Molecules. Adv. Mater. 2005, 17, 2531–2544, doi:10.1002/adma.200500328.
  72. Chirvony, V.; Bolotin, V.; Matveeva, E.; Parkhutik, V. Fluorescence and 1O2 generation properties of porphyrin molecules immobilized in oxidized nano-porous silicon matrix. J. Photochem. Photobiol. A Chem. 2006, 181, 106–113, doi:10.1016/j.jphotochem.2005.11.008.
  73. Gongalsky, M.; Konstantinova, E.A.; Osminkina, L.; Timoshenko, V.Y. Detection of singlet oxygen in photoexcited porous silicon nanocrystals by photoluminescence measurements. Semiconductors 2010, 44, 89–92, doi:10.1134/s106378261001015x.
  74. Konstantinova, E.A.; Demin, V.A.; Timoshenko, V.Y.; Kashkarov, P.K. EPR diagnostics of the photosensitized generation of singlet oxygen on the surface of silicon nanocrystals. JETP Lett. 2007, 85, 59–62, doi:10.1134/s0021364007010122.
  75. Konstantinova, E.A.; Demin, V.A.; Timoshenko, V.Y. Investigation of the generation of singlet oxygen in ensembles of photoexcited silicon nanocrystals by electron paramagnetic resonance spectroscopy. J. Exp. Theor. Phys. 2008, 107, 473–481, doi:10.1134/s1063776108090148.
  76. Fujii, M.; Usui, M.; Hayashi, S.; Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Timoshenko, V.Y. Singlet oxygen formation by porous Si in solution. Phys. Status Solidi A 2005, 202, 1385–1389, doi:10.1002/pssa.200461107.
  77. Cullis, A.G.; Canham, L.T.; Calcott, P.D.J. The structural and luminescence properties of porous silicon. J. Appl. Phys. 1997, 82, 909–965, doi:10.1063/1.366536.
  78. Dexter, D.L. A Theory of Sensitized Luminescence in Solids. J. Chem. Phys. 1953, 21, 836, doi:10.1063/1.1699044.
  79. Palenov, D.A.; Zhigunov, D.M.; Shalygina, O.A.; Kashkarov, P.K.; Timoshenko, V.Y. Specific features of dissipation of electronic excitation energy in coupled molecular solid systems based on silicon nanocrystals on intense optical pumping. Semiconductors 2007, 41, 1351–1355, doi:10.1134/s1063782607110140.
  80. Delerue, C.; Lannoo, M.; Allan, G.; Martin, E.; Mihalcescu, I.; Vial, J.C.; Romestain, R.; Muller, F.; Bsiesy, A. Auger and Coulomb Charging Effects in Semiconductor Nanocrystallites. Phys. Rev. Lett. 1995, 75, 2228–2231, doi:10.1103/PhysRevLett.75.2228.
  81. Kovalev, D.; Gross, E.; Diener, J.; Timoshenko, V.Y.; Fujii, M. Photodegradation of porous silicon induced by photogenerated singlet oxygen molecules. Appl. Phys. Lett. 2004, 85, 3590, doi:10.1063/1.1804241.
  82. Langmuir, I. The constitution and fundamental properties of solids and liquids. Part I. Solids. J. Am. Chem. Soc. 1916, 38, 2221–2295, doi:10.1021/ja02268a002.
  83. Ryabchikov, Y.V.; Belogorokhov, I.A.; Vorontsov, A.S.; Osminkina, L.; Timoshenko, V.Y.; Kashkarov, P.K. Dependence of the singlet oxygen photosensitization efficiency on morphology of porous silicon. Phys. Status Solidi A 2007, 204, 1271–1275, doi:10.1002/pssa.200674306.
  84. Konstantinova, E.; Demin, V.; Vorontzov, A.; Ryabchikov, Y.V.; Belogorokhov, I.; Osminkina, L.; Forsh, P.; Kashkarov, P.; Timoshenko, V.Y. Electron-paramagnetic resonance and photoluminescence study of Si nanocrystals-photosensitizers of singlet oxygen molecules. J. Non Cryst. Solids 2006, 352, 1156–1159, doi:10.1016/j.jnoncrysol.2005.12.017.
  85. Cantin, J.L.; Schoisswohl, M.; Van Bardeleben, H.J.; Zoubir, N.H.; Vergnat, M. Electron-paramagnetic-resonance study of the microscopic structure of the Si(001)-SiO2 interface. Phys. Rev. B 1995, 52, R11599–R11602, doi:10.1103/physrevb.52.r11599.
  86. Rioux, D.; Laferrière, M.; Douplik, A.; Shah, D.; Lilge, L.; Kabashin, A.V.; Meunier, M.M. Silicon nanoparticles produced by femtosecond laser ablation in water as novel contamination-free photosensitizers. J. Biomed. Opt. 2009, 14, 1–4, doi:10.1117/1.3086608.
  87. Timoshenko, V.Y.; Kudryavtsev, A.A.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Belogorokhov, I.A.; Kovalev, D.; Kashkarov, P.K. Silicon nanocrystals as photosensitizers of active oxygen for biomedical applications. JETP Lett. 2006, 83, 423–426, doi:10.1134/s0021364006090128.
  88. Timoshenko, V.Y.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Gongalsky, M.; Efimova, A.I.; Konstantinova, E.A.; Bazylenko, T.Y.; Kashkarov, P.K.; Kudriavtsev, A.A. Silicon nanocrystals as efficient photosensitizer of singlet oxygen for biomedical applications. SPIE Proc. 2007, 6606, 66061E, doi:10.1117/12.729523.
  89. Xiao, L.; Gu, L.; Howell, S.B.; Sailor, M. Porous Silicon Nanoparticle Photosensitizers for Singlet Oxygen and Their Phototoxicity against Cancer Cells. ACS Nano 2011, 5, 3651–3659, doi:10.1021/nn1035262.
  90. Osminkina, L.; Tamarov, K.P.; Sviridov, A.P.; Galkin, R.A.; Gongalsky, M.B.; Solovyev, V.V.; Kudryavtsev, A.A.; Timoshenko, V.Y. Photoluminescent biocompatible silicon nanoparticles for cancer theranostic applications. J. Biophotonics 2012, 5, 529–535, doi:10.1002/jbio.201100112.
  91. Fujii, M.; Kovalev, D.; Goller, B.D.; Minobe, S.; Hayashi, S.; Timoshenko, V.Y. Time-resolved photoluminescence studies of the energy transfer from excitons confined in Si nanocrystals to oxygen molecules. Phys. Rev. B 2005, 72, 165321, doi:10.1103/physrevb.72.165321.
  92. Canham, L.T. Nanoscale semiconducting silicon as a nutritional food additive. Nanotechnology 2007, 18, 185704, doi:10.1088/0957-4484/18/18/185704.
  93. Park, J.-H.; Gu, L.; Von Maltzahn, G.; Ruoslahti, E.; Bhatia, S.N.; Sailor, M.J. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nat. Mater. 2009, 8, 331–336, doi:10.1038/nmat2398.
  94. Dolmans, D.E.J.G.J.; Fukumura, D.; Jain, R.K. Photodynamic therapy for cancer. Nat. Rev. Cancer 2003, 3, 380–387, doi:10.1038/nrc1071.
  95. Gongalsky, M.B.; Kargina, Y.V.; Osminkina, L.; Perepukhov, A.M.; Gulyaev, M.; Vasiliev, A.; Pirogov, Y.A.; Maximychev, A.V.; Timoshenko, V.Y. Porous silicon nanoparticles as biocompatible contrast agents for magnetic resonance imaging. Appl. Phys. Lett. 2015, 107, 233702, doi:10.1063/1.4937731.
  96. Kargina, Y.V.; Gongalsky, M.B.; Perepukhov, A.M.; Gippius, A.A.; Minnekhanov, A.A.; Zvereva, E.A.; Maximychev, A.V.; Timoshenko, V.Y. Investigation of proton spin relaxation in water with dispersed silicon nanoparticles for potential magnetic resonance imaging applications. J. Appl. Phys. 2018, 123, 1–6, doi:10.1063/1.5006846.
  97. Von Bardeleben, H.J.; Stiévenard, D.; Grosman, A.; Ortega, C.; Siejka, J. Defects in porous p-type Si: An electron-paramagnetic-resonance study. Phys. Rev. B 1993, 47, 10899–10902, doi:10.1103/physrevb.47.10899.
  98. Pereira, R.N.; Niesar, S.; Wiggers, H.; Brandt, M.S.; Stutzmann, M.S. Depassivation kinetics in crystalline silicon nanoparticles. Phys. Rev. B 2013, 88, 155430, doi:10.1103/physrevb.88.155430.
  99. Rohrer, M.; Bauer, H.; Mintorovitch, J.; Requardt, M.; Weinmann, H.-J. Comparison of Magnetic Properties of MRI Contrast Media Solutions at Different Magnetic Field Strengths. Investig. Radiol. 2005, 40, 715–724, doi:10.1097/01.rli.0000184756.66360.d3.
  100. Araki, K.; Uchiyama, M.K.; Toma, S.; Rodrigues, S.F.; Shimada, A.L.B.; Loiola, R.A.; Rodríguez, H.J.C.; Oliveira, P.V.; Luz, M.S.; Rabbani, S.R.; et al. Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool. Int. J. Nanomed. 2015, 10, 4731–4746, doi:10.2147/IJN.S83150.
  101. Kargina, Y.V.; Perepukhov, A.M.; Kharin, A.Y.; Zvereva, E.A.; Koshelev, A.V.; Zinovyev, S.V.; Maximychev, A.V.; Alykova, A.F.; Sharonova, N.V.; Zubov, V.P.; et al. Silicon Nanoparticles Prepared by Plasma‐Assisted Ablative Synthesis: Physical Properties and Potential Biomedical Applications. Phys. Status Solidi A 2019, 216, 1800897, doi:10.1002/pssa.201800897.
  102. Noginova, N.; Chen, F.; Weaver, T.; Giannelis, E.P.; Bourlinos, A.B.; Atsarkin, V.A. Magnetic resonance in nanoparticles: Between ferro- and paramagnetism. J. Phys. Condens. Matter 2007, 19, 246208, doi:10.1088/0953-8984/19/24/246208.
  103. Kargina, Y.V.; Zinovyev, S.V.; Perepukhov, A.M.; Suslova, E.V.; Ischenko, A.A.; Timoshenko, V.Y. Silicon nanoparticles with iron impurities for multifunctional applications. Funct. Mater. Lett. 2020, 13, 2040007, doi:10.1142/s179360472040007x.
  104. Bouchoucha, M.; Van Heeswijk, R.B.; Gossuin, Y.; Kleitz, F.; Fortin, M.-A. Fluorinated Mesoporous Silica Nanoparticles for Binuclear Probes in 1H and 19F Magnetic Resonance Imaging. Langmuir 2017, 33, 10531–10542, doi:10.1021/acs.langmuir.7b01792.
  105. Greish, Kh. Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting, Methods Mol. Biol. 2010, 624, 25–37, doi:10.1007/978-1-60761-609-2_3.
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