Different nanostructured coatings and surface finishing, characterized by length range between 1 and 100 nm, may be deposited on the external area of a matrix to implement or enhance the materials efficiency for several applications.The use of polymers combined with nanomaterials or functional nanocarriers in drug-delivery systems finds their main application in the medical sector, in particular in cancer diagnostics and therapy and in traditional oral delivery systems. As a matter of fact, in wastewater treatment the simplest and most efficient methodology to modify the surface properties of filtering membranes, thus improving their retention and regeneration properties, involves the use of membrane coatings based on nanomaterials.