Abnormal Microenvironment Responsive MRI Nanoprobe: Comparison
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Please note this is a comparison between Version 2 by Lindsay Dong and Version 1 by Zhenqi Jiang.

Magnetic resonance imaging (MRI) is often used to diagnose diseases due to its high spatial, temporal and soft tissue resolution. Environment-responsive or smart MRI nanoprobes can specifically target cells based on differences in the cellular environment and improve the contrast between diseased tissues and normal tissues.

  • MRI nanoprobe
  • environment responsive
  • design
  • application
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References

  1. Jun, H.Y.; Yin, H.H.; Kim, S.H.; Park, S.H.; Kim, H.S.; Yoon, K.H. Visualization of tumor angiogenesis using MR imaging contrast agent Gd-DTPA-anti-VEGF receptor 2 antibody conjugate in a mouse tumor model. Korean J. Radiol. 2010, 11, 449–456.
  2. Tan, M.; Burden-Gulley, S.M.; Li, W.; Wu, X.; Lindner, D.; Brady-Kalnay, S.M.; Gulani, V.; Lu, Z.R. MR molecular imaging of prostate cancer with a peptide-targeted contrast agent in a mouse orthotopic prostate cancer model. Pharm. Res. 2012, 29, 953–960.
  3. Torchilin, V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv. Drug Deliv. Rev. 2011, 63, 131–135.
  4. Zhu, J.; He, K.; Dai, Z.; Gong, L.; Zhou, T.; Liang, H.; Liu, J. Self-Assembly of Luminescent Gold Nanoparticles with Sensitive pH-Stimulated Structure Transformation and Emission Response toward Lysosome Escape and Intracellular Imaging. Anal. Chem. 2019, 91, 8237–8243.
  5. Webb, B.A.; Chimenti, M.; Jacobson, M.P.; Barber, D.L. Dysregulated pH: A perfect storm for cancer progression. Nat. Rev. Cancer 2011, 11, 671–677.
  6. Zhang, X.; Lin, Y.; Gillies, R.J. Tumor pH and its measurement. J. Nucl. Med. 2010, 51, 1167–1170.
  7. Monica, C. Activatable probes for diagnosis and biomarker detection by MRI. J. Mater. Chem. B 2017, 5, 4332–4347.
  8. Kang-Kang, Y.; Kun, L.; Chun-Yan, L.; Yong-Mei, X.; Yan-Hong, L.; Qian, Z.; Jin-Ku, B.; Xiao-Qi, Y. Multifunctional gold nanoparticles as smart nanovehicles with enhanced tumour-targeting abilities for intracellular pH mapping and in vivo MR/fluorescence imaging. Nanoscale 2020, 12, 2002–2010.
  9. Ye, D.; Shuhendler, A.J.; Pandit, P.; Brewer, K.D.; Tee, S.S.; Cui, L.; Tikhomirov, G.; Rutt, B.; Rao, J. Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem. Sci. 2014, 4, 3845–3852.
  10. Nejadnik, H.; Ye, D.; Lenkov, O.D.; Donig, J.S.; Martin, J.E.; Castillo, R.; Derugin, N.; Sennino, B.; Rao, J.; Daldrup-Link, H. Magnetic resonance imaging of stem cell apoptosis in arthritic joints with a caspase activatable contrast agent. ACS Nano 2015, 9, 1150–1160.
  11. Changkui, F.; Joyce, T.; Aidan, P.; Tianqing, L.; Cheng, Z.; Xiao, T.; Felicity, H.; Hui, P.; Whittaker, A.K. Fluorinated Glycopolymers as Reduction-responsive 19F MRI Agents for Targeted Imaging of Cancer. Biomacromolecules 2019, 20, 2043–2050.
  12. Mi, P.; Kokuryo, D.; Cabral, H.; Wu, H.; Terada, Y.; Saga, T.; Aoki, I.; Nishiyama, N.; Kataoka, K. A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy. Nat. Nanotechnol. 2016, 11, 724–730.
  13. Zhao, Z.; Wang, X.; Zhang, Z.; Zhang, H.; Liu, H.; Zhu, X.; Li, H.; Chi, X.; Yin, Z.; Gao, J. Real-time monitoring of arsenic trioxide release and delivery by activatable T(1) imaging. ACS Nano 2015, 9, 2749–2759.
  14. Hsu, B.Y.; Ng, M.; Tan, A.; Connell, J.; Roberts, T.; Lythgoe, M.; Zhang, Y.; Wong, S.Y.; Bhakoo, K.; Seifalian, A.M.; et al. pH-Activatable MnO-Based Fluorescence and Magnetic Resonance Bimodal Nanoprobe for Cancer Imaging. Adv. Healthc. Mater. 2016, 5, 721–729.
  15. Kim, H.J.; Matsuda, H.; Zhou, H.; Honma, I. Ultrasound-Triggered Smart Drug Release from a Poly(dimethylsiloxane)–Mesoporous Silica Composite. Adv. Mater. 2006, 18, 3083–3088.
  16. Yang, H.Y.; Jang, M.S.; Gao, G.H.; Lee, J.H.; Lee, D.S. pH-Responsive biodegradable polymeric micelles with anchors to interface magnetic nanoparticles for MR imaging in detection of cerebral ischemic area. Nanoscale 2016, 8, 12588–12598.
  17. Preslar, A.T.; Tantakitti, F.; Park, K.; Zhang, S.; Stupp, S.I.; Meade, T.J. (19)F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape. ACS Nano 2016, 10, 7376–7384.
  18. Chen, S.; Yang, Y.; Li, H.; Zhou, X.; Liu, M. pH-Triggered Au-fluorescent mesoporous silica nanoparticles for 19F MR/fluorescent multimodal cancer cellular imaging. Chem. Commun. (Camb) 2014, 50, 283–285.
  19. Huang, X.; Huang, G.; Zhang, S.; Sagiyama, K.; Togao, O.; Ma, X.; Wang, Y.; Li, Y.; Soesbe, T.C.; Sumer, B.D.; et al. Multi-chromatic pH-activatable 19F-MRI nanoprobes with binary ON/OFF pH transitions and chemical-shift barcodes. Angew. Chem. Int. Ed. Engl. 2013, 52, 8074–8078.
  20. Mac Manus, M.P.; Hicks, R.J. The role of positron emission tomography/computed tomography in radiation therapy planning for patients with lung cancer. Semin Nucl. Med. 2012, 42, 308–319.
  21. Wang, S.; Zhou, Z.; Wang, Z.; Liu, Y.; Jacobson, O.; Shen, Z.; Fu, X.; Chen, Z.Y.; Chen, X. Gadolinium Metallofullerene-Based Activatable Contrast Agent for Tumor Signal Amplification and Monitoring of Drug Release. Small 2019, 15, 1900691.
  22. Mizukami, S.; Takikawa, R.; Sugihara, F.; Hori, Y.; Tochio, H.; Walchli, M.; Shirakawa, M.; Kikuchi, K. Paramagnetic relaxation-based 19f MRI probe to detect protease activity. J. Am. Chem. Soc. 2008, 130, 794–795.
  23. Yue, X.; Wang, Z.; Zhu, L.; Wang, Y.; Qian, C.; Ma, Y.; Kiesewetter, D.O.; Niu, G.; Chen, X. Correction to "Novel (19)F Activatable Probe for the Detection of Matrix Metalloprotease-2 Activity by MRI/MRS". Mol. Pharm. 2017, 14, 1317–1318.
  24. Zheng, Z.; Sun, H.; Hu, C.; Li, G.; Liu, X.; Chen, P.; Cui, Y.; Liu, J.; Wang, J.; Liang, G. Using “On/Off” (19)F NMR/Magnetic Resonance Imaging Signals to Sense Tyrosine Kinase/Phosphatase Activity in Vitro and in Cell Lysates. Anal. Chem. 2016, 88, 3363–3368.
  25. Loving, G.S.; Caravan, P. Activation and retention: A magnetic resonance probe for the detection of acute thrombosis. Angew. Chem. Int. Ed. Engl. 2014, 53, 1140–1143.
  26. Cheng, Z.; Tsourkas, A. Monitoring phospholipase A(2) activity with Gd-encapsulated phospholipid liposomes. Sci. Rep. 2014, 4, 6958.
  27. Eyk, S.; Franziska, R.; Carsten, W.; Matthias, T.; Bernd, H.; Jörg, S. Protease-specific nanosensors for magnetic resonance imaging. Bioconjugate Chem. 2008, 19, 2440–2445.
  28. Ansari, C.; Tikhomirov, G.A.; Hong, S.H.; Falconer, R.A.; Loadman, P.M.; Gill, J.H.; Castaneda, R.; Hazard, F.K.; Tong, L.; Lenkov, O.D.; et al. Development of novel tumor-targeted theranostic nanoparticles activated by membrane-type matrix metalloproteinases for combined cancer magnetic resonance imaging and therapy. Small 2014, 10, 566–575.
  29. Daryaei, I.; Ghaffari, M.M.; Jones, K.M.; Pagel, M.D. Detection of Alkaline Phosphatase Enzyme Activity with a CatalyCEST MRI Biosensor. ACS Sens. 2016, 1, 857–861.
  30. Kim, M.H.; Son, H.Y.; Kim, G.Y.; Park, K.; Huh, Y.M.; Haam, S. Redoxable heteronanocrystals functioning magnetic relaxation switch for activatable T1 and T2 dual-mode magnetic resonance imaging. Biomaterials 2016, 101, 121–130.
  31. Tanaka, K.; Kitamura, N.; Takahashi, Y.; Chujo, Y. Reversible signal regulation system of 19F NMR by redox reactions using a metal complex as a switching module. Bioorg. Med. Chem. 2009, 17, 3818–3823.
  32. Munoz Ubeda, M.; Carniato, F.; Catanzaro, V.; Padovan, S.; Grange, C.; Porta, S.; Carrera, C.; Tei, L.; Digilio, G. Gadolinium-Decorated Silica Microspheres as Redox-Responsive MRI Probes for Applications in Cell Therapy Follow-Up. Chemistry (Weinheim an der Bergstrasse, Germany) 2016, 22, 7716–7720.
  33. Nakamura, T.; Matsushita, H.; Sugihara, F.; Yoshioka, Y.; Mizukami, S.; Kikuchi, K. Activatable 19F MRI nanoparticle probes for the detection of reducing environments. Angew. Chem. Int. Ed. Engl. 2015, 54, 1007–1010.
  34. Kadakia, R.T.; Da, X.; Hongyu, G.; Bailey, B.; Meng, Y.; Que, E.L. Responsive fluorinated nanoemulsions for 19F magnetic resonance detection of cellular hypoxia. Dalton Trans. 2020, 49, 16419–16424.
  35. Xie, D.; Kim, S.; Kohli, V.; Banerjee, A.; Yu, M.; Enriquez, J.S.; Luci, J.J.; Que, E.L. Hypoxia-Responsive (19)F MRI Probes with Improved Redox Properties and Biocompatibility. Inorg. Chem. 2017, 56, 6429–6437.
  36. Deng, K.; Wu, B.; Wang, C.X.; Wang, Q.; Yu, H.; Li, J.M.; Li, K.H.; Zhao, H.Y.; Huang, S.W. An Oxidation-Enhanced Magnetic Resonance Imaging Probe for Visual and Specific Detection of Singlet Oxygen Generated in Photodynamic Cancer Therapy In Vivo. Adv. Healthc. Mater. 2020, 9, e2000533.
  37. Yaqin, H.; Caizhi, L.; Xiandeng, H.; Lan, W. Mono-dispersed nano-hydroxyapatite based MRI probe with tetrahedral DNA nanostructures modification for in vitro tumor cell imaging. Anal. Chim. Acta 2020, 1138, 141–149.
  38. Bond, C.J.; Cineus, R.; Nazarenko, A.Y.; Spernyak, J.A.; Morrow, J.R. Isomeric Co(ii) paraCEST agents as pH responsive MRI probes. Dalton Trans. 2020, 49, 279–284.
  39. Akam, E.A.; Eric, A.; Rotile, N.J.; Slattery, H.R.; Zhou, I.Y.; Michael, L.; Peter, C. Improving the reactivity of hydrazine-bearing MRI probes for in vivo imaging of lung fibrogenesis. Chem. Sci. 2020, 11, 224–231.
  40. Meng, Y.; Da, X.; Kadakia, R.T.; Weiran, W.; Que, E.L. Harnessing chemical exchange:F-19 magnetic resonance OFF/ON zinc sensing with a Tm(iii) complex. Chem. Commun. Camb. Engl. 2020, 56, 6257–6260.
  41. Xie, D.; Yu, M.; Xie, Z.L.; Kadakia, R.T.; Chung, C.; Ohman, L.E.; Javanmardi, K.; Que, E.L. Versatile Nickel(II) Scaffolds as Coordination-Induced Spin-State Switches for (19) F Magnetic Resonance-Based Detection. Angew. Chem. Int. Ed. Engl. 2020, 59, 22523–22530.
  42. Gao, Z.; Hou, Y.; Zeng, J.; Chen, L.; Liu, C.; Yang, W.; Gao, M. Tumor Microenvironment-Triggered Aggregation of Antiphagocytosis (99m) Tc-Labeled Fe3 O4 Nanoprobes for Enhanced Tumor Imaging In Vivo. Adv. Mater. 2017, 29, 1701095.
  43. Peng, Q.; Li, Y.; Bo, S.; Yuan, Y.; Yang, Z.; Chen, S.; Zhou, X.; Jiang, Z.X. Paramagnetic nanoemulsions with unified signals for sensitive (19)F MRI cell tracking. Chem. Commun. (Camb.) 2018, 54, 6000–6003.
  44. Bo, S.; Yuan, Y.; Chen, Y.; Yang, Z.; Chen, S.; Zhou, X.; Jiang, Z.X. In vivo drug tracking with (19)F MRI at therapeutic dose. Chem. Commun. (Camb.) 2018, 54, 3875–3878.
  45. Rajkumar, S.; Prabaharan, M. Multi-functional core-shell Fe3O4@Au nanoparticles for cancer diagnosis and therapy. Colloids Surf. B Biointerfaces 2019, 174, 252–259.
  46. Gholipour, N.; Akhlaghi, M.; Kheirabadi, A.M.; Geramifar, P.; Beiki, D. Development of Ga-68 labeled, biotinylated thiosemicarbazone dextran-coated iron oxide nanoparticles as multimodal PET/MRI probe. Int. J. Biol. Macromol. 2020, 148, 932–941.
  47. Leszek, J.; Md Ashraf, G.; Tse, W.H.; Zhang, J.; Gasiorowski, K.; Avila-Rodriguez, M.F.; Tarasov, V.V.; Barreto, G.E.; Klochkov, S.G.; Bachurin, S.O.; et al. Nanotechnology for Alzheimer Disease. Curr. Alzheimer Res. 2017, 14, 1182–1189.
  48. Azria, D.; Blanquer, S.; Verdier, J.M.; Belamie, E. Nanoparticles as contrast agents for brain nuclear magnetic resonance imaging in Alzheimer’s disease diagnosis. J. Mater. Chem. B 2017, 5, 7216–7237.
  49. Kieger, A.; Wiester, M.J.; Procissi, D.; Parrish, T.B.; Mirkin, C.A.; Thaxton, C.S. Hybridization-induced "off-on" 19F-NMR signal probe release from DNA-functionalized gold nanoparticles. Small 2011, 7, 1977–1981.
  50. Sicilia, G.; Davis, A.L.; Spain, S.G.; Magnusson, J.P.; Boase, N.R.B.; Thurecht, K.J.; Alexander, C. Synthesis of 19F nucleic acid–polymer conjugates as real-time MRI probes of biorecognition. Polym. Chem. 2016, 7, 2180–2191.
  51. Pais, A.; Degani, H. Estrogen Receptor-Targeted Contrast Agents for Molecular Magnetic Resonance Imaging of Breast Cancer Hormonal Status. Front. Oncol. 2016, 6, 100.
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