Alopecia: Comparison
View Latest Version
Please note this is a comparison between Version 2 by Camila Xu and Version 1 by Matej Žnidarič.

Hair loss (HL), also known as alopecia or baldness, is a common clinical disorder that affects millions of people worldwide and often causes a significant source of patient distress.

  • hair follicle
  • alopecia
  • dermal papilla cells
  • hair transplantation
Please wait, diff process is still running!

References

  1. Owczarczyk-Saczonek, A.; Krajewska-Włodarczyk, M.; Kruszewska, A.; Banasiak, Ł.; Placek, W.; Maksymowicz, W. Therapeutic Potential of Stem Cells in Follicle Regeneration. Stem Cells Int. 2018, 2018, 1049641. Available online: (accessed on 17 October 2020).
  2. Vary, J.C., Jr. Selected Disorders of Skin Appendages—Acne, Alopecia, Hyperhidrosis. Med. Clin. N. Am. 2015, 99, 1195–1211.
  3. Mirmirani, P.; Willey, A.; Headington, J.T.; Stenn, K.; McCalmont, T.H.; Price, V.H. Primary cicatricial alopecia: Histo-pathologic findings do not distinguish clinical variants. J. Am. Acad. Dermatol. 2005, 52, 637–643.
  4. Harries, M.J.; Sinclair, R.D.; Macdonald-Hull, S.; Whiting, D.A.; Griffiths, C.E.; Paus, R. Management of primary cicatricial alopecias: Options for treatment. Br. J. Dermatol. 2008, 159, 1–22.
  5. Harries, M.J.; Paus, R. The Pathogenesis of Primary Cicatricial Alopecias. Am. J. Pathol. 2010, 177, 2152–2162.
  6. Hassan, A.S. Surgical treatment of secondary cicatricial alopecia of scalp and eyebrow. Indian J. Plast. Surg. 2009, 42, 63–67. Available online: (accessed on 14 October 2020).
  7. Olsen, E.A.; Bergfeld, W.F.; Cotsarelis, G.; Price, V.H.; Shapiro, J.; Sinclair, R.; Solomon, A.; Sperling, L.; Stenn, K.; Whiting, D.A. Summary of North American Hair Re-search Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001. J. Am. Acad. Dermatol. 2003, 48, 103–110.
  8. Whiting, D.A. Cicatricial alopecia: Clinico-pathological findings and treatment. Clin. Dermatol. 2001, 19, 211–225.
  9. Filbrandt, R.; Rufaut, N.; Jones, L.; Sinclair, R. Primary cicatricial alopecia: Diagnosis and treatment. Can. Med. Assoc. J. 2013, 185, 1579–1585.
  10. Darwin, E.; Hirt, P.A.; Fertig, R.; Doliner, B.; Delcanto, G.; Jimenez, J.J. Alopecia Areata: Review of Epidemiology, Clinical Features, Pathogenesis, and New Treatment Options. Int. J. Trichol. 2018, 10, 51–60. Available online: (accessed on 20 May 2020).
  11. Qi, J.; Garza, L.A. An Overview of Alopecias. Cold Spring Harb. Perspect. Med. 2014, 4, a013615.
  12. Hordinsky, M.K. Medical Treatment of Noncicatricial Alopecia. Semin. Cutan. Med. Surg. 2006, 25, 51–55.
  13. Hughes, E.C.; Saleh, D. Telogen Effluvium. In StatPearls; StatPearls Publishing: Treasure Island, FL, USA, 2021.
  14. Randall, V.A.; Sundberg, J.P.; Philpott, M.P. Animal and in vitro models for the study of hair follicles. In Journal of Investigative Dermatology Symposium Proceedings; Blackwell Publishing Inc.: Hoboken, NJ, USA, 2003; pp. 39–45.
  15. Korosec, A.; Lichtenberger, B.M. In vitro models to study hair follicle generation. Skin Tissue Models Regen. Med. 2018, 279–301.
  16. Choi, S.; Zhang, B.; Ma, S.; Gonzalez-Celeiro, M.; Stein, D.; Jin, X.; Kim, S.T.; Kang, Y.-L.; Besnard, A.; Rezza, A.; et al. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence. Nat. Cell Biol. 2021, 1–5.
  17. Higgins, C.A.; Richardson, G.D.; Ferdinando, D.; Westgate, G.E.; Jahoda, C.A. Modelling the hair follicle dermal papilla using spheroid cell cultures. Exp. Dermatol. 2010, 19, 546–548.
  18. Langan, E.A.; Philpott, M.P.; Kloepper, J.E.; Paus, R. Human hair follicle organ culture: Theory, application and perspectives. Exp. Dermatol. 2015, 24, 903–911.
  19. Kwack, M.H.; Yang, J.M.; Won, G.H.; Kim, M.K.; Kim, J.C.; Sung, Y.K. Establishment and characterization of five immor-talized human scalp dermal papilla cell lines. Biochem. Biophys. Res. Commun. 2018, 496, 346–351.
  20. Topouzi, H.; Logan, N.J.; Williams, G.; Higgins, C.A. Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles; Blackwell Publishing Ltd.: Hoboken, NJ, USA, 2017; Volume 26, pp. 491–496.
  21. Soma, T.; Tajima, M.; Kishimoto, J. Hair cycle-specific expression of versican in human hair follicles. J. Dermatol. Sci. 2005, 39, 147–154.
  22. Miao, Y.; Bin Sun, Y.; Liu, B.C.; Jiang, J.D.; Hu, Z.Q. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture. Tissue Eng. Part A 2014, 20, 2329–2338.
  23. Gupta, A.C.; Chawla, S.; Hegde, A.; Singh, D.; Bandyopadhyay, B.; Lakshmanan, C.C.; Kalsi, G.; Ghosh, S. Establishment of an in vitro organoid model of dermal papilla of human hair follicle. J. Cell. Physiol. 2018, 233, 9015–9030.
  24. Lee, L.F.; Chuong, C.M. Building Complex. Tissues: High. Throughput Screening for Molecules Required in Hair Engineering; Nature Publishing Group: Berlin, German, 2009; Volume 129, pp. 815–817.
  25. Lin, B.; Miao, Y.; Wang, J.; Fan, Z.; Du, L.; Su, Y.; Liu, B.; Hu, Z.; Xing, M. Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroid of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Re-generation. ACS Appl. Mater. Interfaces 2016, 8, 5906–5916.
  26. Kageyama, T.; Yoshimura, C.; Myasnikova, D.; Kataoka, K.; Nittami, T.; Maruo, S.; Fukuda, J. Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine. Biomaterials 2018, 154, 291–300.
  27. Tan, J.J.Y.; Common, J.E.; Wu, C.; Ho, P.C.L.; Kang, L. Keratinocytes maintain compartmentalization between dermal pa-pilla and fibroblasts in 3D heterotypic tri-cultures. Cell Prolif. 2019, 52.
  28. Abaci, H.E.; Coffman, A.; Doucet, Y.; Chen, J.; Jacków, J.; Wang, E.; Guo, Z.; Shin, J.U.; Jahoda, C.A.; Christiano, A.M. Tissue engineering of human hair follicles using a biomimetic developmental approach. Nat. Commun. 2018, 9, 1–11.
  29. Zhang, X.; Xiao, S.; Liu, B.; Miao, Y.; Hu, Z. Use of extracellular matrix hydrogel from human placenta to restore hair-inductive potential of dermal papilla cells. Regen. Med. 2019, 14, 741–751.
  30. Driskell, R.R.; Clavel, C.; Rendl, M.; Watt, F.M. Hair follicle dermal papilla cells at a glance. J. Cell Sci. 2011, 124, 1179–1182.
  31. Ohyama, M.; Kobayashi, T.; Sasaki, T.; Shimizu, A.; Amagai, M. Restoration of the intrinsic properties of human dermal papilla in vitro. J. Cell Sci. 2012, 125, 4114–4125.
  32. Havlíčková, B.; Biro, T.; Mescalchin, A.; Arenberger, P.; Paus, R. Towards optimization of an organotypic assay system that imitates human hair follicle-like epithelial-mesenchymal interactions. Br. J. Dermatol. 2004, 151, 753–765.
  33. Huang, Y.C.; Chan, C.C.; Lin, W.T.; Chiu, H.Y.; Tsai, R.Y.; Tsai, T.H.; Chan, J.Y.; Lin, S.J. Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration. Biomaterials 2013, 34, 442–451.
  34. Lin, C.-M.; Li, Y.; Ji, Y.-C.; Huang, K.; Cai, X.-N.; Li, G.-Q. Induction of hair follicle regeneration in rat ear by microencapsulated human hair dermal papilla cells. Chin. J. Traumatol. 2009, 12, 49–54.
  35. Dong, L.; Hao, H.; Liu, J.; Tong, C.; Ti, D.; Chen, D.; Chen, L.; Li, M.; Liu, H.; Fu, X.; et al. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system. J. Tissue Eng. Regen. Med. 2015, 11, 1479–1489.
  36. Gnedeva, K.; Vorotelyak, E.; Cimadamore, F.; Cattarossi, G.; Giusto, E.; Terskikh, V.V.; Terskikh, A.V. Derivation of Hair-Inducing Cell from Human Pluripotent Stem Cells. PLoS ONE 2015, 10, e0116892.
  37. Lindner, G.; Horland, R.; Wagner, I.; Ataç, B.; Lauster, R. De novo formation and ultra-structural characterization of a fiber-producing human hair follicle equivalent in vitro. J. Biotechnol. 2011, 152, 108–112. Available online: (accessed on 18 April 2020).
  38. Castro, A.R.; Logarinho, E. Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far from a Hairy Goal? John Wiley and Sons Ltd.: Hoboken, NJ, USA, 2020; Volume 9, pp. 342–350.
  39. Takagi, R.; Ishimaru, J.; Sugawara, A.; Toyoshima, K.-E.; Ishida, K.; Ogawa, M.; Sakakibara, K.; Asakawa, K.; Kashiwakura, A.; Oshima, M.; et al. Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model. Sci. Adv. 2016, 2, e1500887. Available online: (accessed on 4 July 2020).
  40. Yen, C.M.; Chan, C.C.; Lin, S.J. High-throughput reconstitution of epithelial-mesenchymal interaction in fol-liculoid microtissues by biomaterial-facilitated self-assembly of dissociated heterotypic adult cells. Biomaterials 2010, 31, 4341–4352.
  41. Tan, J.J.Y.; Nguyen, D.-V.; Common, J.E.; Wu, C.; Ho, P.C.L.; Kang, L. Investigating PEGDA and GelMA Microgel Models for Sustained 3D Heterotypic Dermal Papilla and Keratinocyte Co-Cultures. Int. J. Mol. Sci. 2021, 22, 2143.
  42. Almeida, A.; Sarmento, B.; Rodrigues, F. Insights on In Vitro Models for Safety and Toxicity Assessment of Cosmetic In-Gredients; Elsevier, B.V.: Amsterdam, The Netherlands, 2017; Volume 519, pp. 178–185.
  43. Madaan, A.; Verma, R.; Singh, A.T.; Jaggi, M. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model. for Hair Growth; Blackwell Publishing Ltd.: Hoboken, NJ, USA, 2018; Volume 40, pp. 429–450.
  44. Abbott, A. The lowdown on animal testing for cosmetics. Nature 2009.
More
© Text is available under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
Feedback