Blum et al., 1999 [16] | Blum et al., 1999 [23] |
In vitro |
Mandibular incisors |
ProFile |
Step-back & crown-down |
Students > Endodontist (T)
Students < Endodontist (F)
Step-back > crown-down |
Blum et al., 1999 [17] | Blum et al., 1999 [32] |
In vitro |
Mandibular incisors |
ProFile |
Step-back & crown-down |
Contact area- 10 mm (Step-back) and 5 mm (crown-down) from the tip
Step-back > crown-down (T & F) |
Sattapan et al., 2000 [18] | Sattapan et al., 2000 [28] |
In vitro |
Maxillary/mandibular central and lateral incisors |
Quantec Series 2000 |
Single file |
Small canal > medium canal |
Peters et al., 2002 [19] | Peters et al., 2002 [17] |
In vitro |
Extracted human teeth/plastic blocks |
Profile |
Crown-down |
Straight canal blocks > curved canal blocks > natural teeth (T)
Curved canal blocks > natural teeth > straight canal blocks (F) |
Peters et al., 2003 [20] | Peters et al., 2003 [29] |
In vitro |
Maxillary molars |
ProTaper |
Single-length |
F3 > F2 > F1 > S1 > S2 (T)
F3 > S1 > F2 > F1 > S2 (F) |
Blum et al., 2003 [21] | Blum et al., 2003 [30] |
In vitro |
Maxillary central incisors/ mandibular central or lateral incisors |
ProTaper |
Single-Length |
Narrow canal > large canal (T)
Large canal > narrow canal (F) |
Hübscher et al., 2003 [22] | Hübscher et al., 2003 [31] |
In vitro |
Maxillary molars |
FlexMaster |
Crown-down-like modified sequence |
Constricted canal > wide canal (T & F) |
Diemer et al., 2004 [13] |
In vitro |
Resin blocks |
Hero |
Single file |
Shorter pitch length > longer pitch length (T & F) |
Da Silva et al., 2005 [23] | Da Silva et al., 2005 [34] |
In vitro |
Maxillary/mandibular central and lateral incisors |
Race 720, Race 721, Profile |
Single-length |
Profile > Race 720 > Race 721 (T & F) |
Schrader et al., 2005 [24] | Schrader et al., 2005 [33] |
In vitro |
Plastic blocks |
Profile |
Crown-down |
35/0.04 had peak T and F in 4% taper sequence
40/0.06 and 35/0.04 had peak T and F in combination of 4% and 6% taper, respectively |
Peters et al., 2005 [25] | Peters et al., 2005 [54] |
In vitro |
Dentin discs |
ProFile, ProTaper |
Single file |
Glyde > Control > EDTA > H | 2 | O for ProFile (T)
Glyde > H | 2 | O > EDTA > Control for ProTaper (T)
Glyde > H | 2 | O > Control > EDTA for ProFile (F)
Control > H | 2 | O > Glyde > EDTA for ProTaper (F)
ProTaper > ProFile (T)
ProFile > ProTaper (F) |
Boessler et al., 2007 [26] | Boessler et al., 2007 [55] |
In vitro |
Dentin discs |
ProFile |
Single file |
Dry Control > NaOCL 1% > H | 2 | O > HEPB 18% (T)
Dry Control > H | 2 | O > NaOCL 1% > HEPB 18% (F) |
Boessler et al., 2009 [27] | Boessler et al., 2009 [56] |
In vitro |
Dentin discs |
ProTaper |
Single-length |
Electropolished > machined (T)
Machined > electropolished (F) |
Diop et al., 2009 [28] | Diop et al., 2009 [40] |
In vitro |
Human cadaveric mandivular central/lateral incisors |
ProTaper |
Single file |
Apical > coronal (T & F)
Right > left (F)
Posterior > anterior (F) |
Ha et al., 2010 [15] |
In vitro |
Resin blocks |
K3, Mtwo, NRT, ProFile, ProTaper |
Single file |
ProTaper > K3 > NRT-safe tip > NRT-active tip > Mtwo > ProFile (F) |
Son et al., 2010 [29] | Son et al., 2010 [18] |
In vitro |
Resin blocks |
ProTaper, ProFile |
Single-length |
0° > 10° > 20° > 30° canal curvature (F) |
Sung et al., 2010 [30] | Sung et al., 2010 [24] |
In vitro |
Resin blocks |
ProFile, GT rotary, K3 |
Single-length |
Greater taper > smaller taper (F) |
Bardsley et al., 2011 [31] | Bardsley et al., 2011 [36] |
In vitro |
Plastic blocks |
Vortex |
Crown-down |
200 rpm > 400 rpm > 600 rpm (T & F) |
Peters et al., 2012 [32] | Peters et al., 2012 [37] |
In vitro |
Plastic blocks |
Hyflex CM |
Single-length & crown-down |
Single-length > crown-down (T & F) |
Ha et al., 2012 [8] |
In vitro |
Endo-training blocks |
PathFile, NiTiFlex, ProTaper |
Single file |
#13 > #15 > #18 > #20 (T & F) |
Diemer et al., 2013 [33] | Diemer et al., 2013 [19] |
In vitro |
Resin blocks |
HeroShaper, Prototypes |
Single file |
H6 > H0 > H4 (T)
H0 > H6 > H4 (F) |
Pereira et al., 2013 [34] | Pereira et al., 2013 [41] |
In vitro |
Plastic blocks |
ProTaper Next |
Single-length |
250 rpm > 300 rpm > 350 rpm (T & F) |
Arias et al., 2014 [35] | Arias et al., 2014 [27] |
In vitro |
Maxillary incisors/mandibular molars |
ProTaper Next, ProTaper Universal |
Single-length |
Small canals > large canals (T & F) |
Pereira et al., 2015 [36] | Pereira et al., 2015 [43] |
In vitro |
Plastic blocks |
ProTaper Universal, Profile Vortex, Vortex Blue, Typhoon Infinite Flex |
Single-length |
Typhoon > ProTaper Universal > Vortex Blue > ProFile Vortex (T)
ProTaper Universal > ProFile Vortex > Vortex Blue > Typhoon (F) |
Ha et al., 2015 [9] |
In vitro |
Resin block |
G-1, G-2, uG glide path files |
Single file |
G-2 > uG > G-1 (F) |
Peixoto et al., 2015 [11] |
In vitro |
Acrylic blocks |
Mtwo, Race, ProTaper Universal |
Single file |
ProTaper Universal > Race > Mtwo (T)
ProTaper Universal > Mtwo > Race (F) |
Arias et al., 2016 [37] | Arias et al., 2016 [35] |
In vitro |
Mandibular molars |
PathFile, ProGlider |
Single-length & Single file |
PathFile 1 > PathFile 2 > ProGlider (T & F)
ProGlider (16/.02, single file) > PathFile (16/.02, Sequence) (T & F) |
Moreinos et al., 2016 [38] | Moreinos et al., 2016 [59] |
In vitro |
Simulated metal block canal |
Gentlefile, ProTaper Next, Revo-S |
Single-length |
ProTaper X1 > Revo-S SC2 > Gentlefile 1 (F)
Revo-S SC3 > ProTaper X2 > Gentlefile 2 (F) |
Kwak et al., 2016 [14] |
In vitro |
Resin blocks |
OneG, pG, OneG heat-treated, pG heat-treated glide path files |
Single file |
pG > OneG > OneG heat-treated > pG heat-treated (F) |
Ha et al., 2016 [4] |
In vitro |
Resin blocks |
Mtwo, Reciproc 25, ProTaper Universal, ProTaper Next |
Single file |
Reciproc 25 > ProTaper Universal > ProTaper Next > Mtwo (F) |
Jamleh et al., 2016 [39] | Jamleh et al., 2016 [51] |
In vitro |
Premolar teeth |
Twisted File, Twisted File Adaptive, ProTaper Universal, ProTaper Next |
Single-length |
ProTaper Universal > ProTaper Next > Twisted File > Twisted File Adaptive (L) |
Arias et al., 2017 [40] | Arias et al., 2017 [26] |
In vitro |
Mandibular molars |
PathFile, ProGlider, ProTaper Gold |
Single-length |
Glide path reduced the torque of shaping files |
Tokita et al., 2017 [41] | Tokita et al., 2017 [47] |
In vitro |
Resin canal models |
Twisted File Adaptive |
Single-length |
CR > torque-sensitive reciprocation > time-dependent reciprocation (T)
Time-dependent reciprocation > CR > torque-sensitive reciprocation (F) |
Ha et al., 2017 [42] | Ha et al., 2017 [45] |
In vitro |
Resin Canals |
One G |
Single-length |
4/6 pecking depath > 2/4 pecking depath (F) |
Fukumori et al., 2018 [43] | Fukumori et al., 2018 [22] |
In vitro |
Resin canals |
EndoWave |
Single file |
EndoWave (30/0.06) > EndoWave (30/0.04) (T & F) |
Kwak et al., 2018 [44] | Kwak et al., 2018 [25] |
In vitro |
Resin blocks |
WaveOne, WaveOne Gold |
Single file |
WaveOne > WaveOne Gold (T)
Without Glide Path > with Glide Path (T) |
Jamleh et al., 2018 [45] | Jamleh et al., 2018 [58] |
In vitro |
Maxillary premolar teeth |
WaveOne, WaveOne Gold |
Single file |
WaveOne > WaveOne Gold (F) |
Nishijo et al., 2018 [46] | Nishijo et al., 2018 [50] |
In vitro |
Endo training blocks |
Hyflex EDM Glide Path File (EDM), Hyflex GPF, Scout Race (Race) |
Single file |
Hyflex EDM Glide Path File > GPF > Race (CR) (F)
Hyflex EDM Glide Path File > Race > Hyflex GPF (Reciprocation) (F) |
Gambarini et al., 2019 [47] | Gambarini et al., 2019 [53] |
In vitro |
Maxillary anterior teeth |
Twisted File |
Single file |
Inward pecking motion > outward brushing motion (T) |
Abu-Tahun et al., 2019 [48] | Abu-Tahun et al., 2019 [46] |
In vitro |
Resin canals |
One G, Hyflex EDM |
Single file |
No glide path > 5 insertions > 10 insertions > 15 insertions > 20 insertions (T) |
Kwak et al., 2019 [49] | Kwak et al., 2019 [20] |
In vitro |
Resin blocks |
ProTaper Universal, ProTaper Gold, WaveOne, WaveOne Gold |
Single-length & Single file |
ProTaper Universal > WaveOne > ProTaper Gold > WaveOne Gold (F) |
Nayak et al., 2019 [50] | Nayak et al., 2019 [52] |
In vitro |
Resin blocks |
WaveOne Gold, Self-adjusting file, 2Shape |
Single-length &single file |
WaveOne Gold > 2Shape 2 > 2Shape 1 > self-adjusting file (F) |
Kwak et al., 2019 [51] | Kwak et al., 2019 [49] |
In vitro |
Resin blocks |
K3XF, Twisted File Adaptive |
Single-length |
K3XF (CR) > K3XF (adaptive motion) > TFA (adaptive motion) (T) |
Maki et al., 2019 [52] | Maki et al., 2019 [42] |
In vitro |
Resin canal blocks |
ProTaper Next |
Single-length |
High and/or medium-speed > low-speed (clockwise T)
High-speed > medium-speed > low-speed (F) |
Gambarini et al., 2019 [53] | Gambarini et al., 2019 [21] |
In vivo |
Double-rooted maxillary premolars |
ProTaper Next, EdgeFile |
Single-length |
ProTaper Next > EdgeFile (T & preparation time) |
Bürklein et al., 2019 [54] | Bürklein et al., 2019 [39] |
In vitro |
Maxillary incisors |
K-flexofile stainless steel, F6 SkyTaper & EndoPilot, DentaPort ZX OTR, VDW.silver |
Balanced-force, single-length |
Balanced-force > rotary (F)
Rotary > balanced-force (T)
No significant differences among 3 motors (T) |
Almeida et al., 2020 [12] |
In vitro |
Acrylic blocks |
ProTaper Next, ProTaper Universal |
Single-length |
ProTaper Next X2 > ProTaper Next X1 > ProTaper Universal S1 > ProTaper Universal F1 (T)
ProTaper Next X1 > ProTaper Universal S2 > ProTaper Next X2 > ProTaper Universal F1 (F) |
Maki et al., 2020 [55] | Maki et al., 2020 [57] |
In vitro |
Resin blocks |
Reciproc, Reciproc Blue |
Single file |
Reciproc > Reciproc Blue (T & F) |
Lee et al., 2020 [3] |
In vitro |
Molars |
ProTaper Next, One Curve, Hyflex EDM, Twisted File Adaptive |
Single-length |
CR > adaptive motion (T)
Hyflex EDM > One Curve > ProTaper Next > Twisted File Adaptive (T) |
Htun et al., 2020 [56] | Htun et al., 2020 [48] |
In vitro |
Mandibular incisors |
Hyflex EDM glide path file, stainless steel K-file |
Single file |
CR > OGP > stainless steel manual (T in positive domain)
CR > stainless steel manual > OGP (T in negative domain)
OGP > stainless steel manual > CR (F in positive domain)
OGP > CR > stainless steel manual (F in negative domain) |
Kimura et al., 2020 [57] | Kimura et al., 2020 [38] |
In vitro |
Resin blocks |
Endowave |
Single file, crown-down |
Single file (CR) > single file (OTR) (clockwise & counterclockwise T)
crown-down (CR) > crown-down (OTR) (clockwise T)
crown-down (OTR) > crown-down (CR) (counterclockwise T) |
Peters et al., 2020 [58] | Peters et al., 2020 [44] |
In vitro |
Plastic blocks |
TruNatomy, ProTaper Next |
Single-length |
ProTaper Next X2 > ProTaper Next X3 > ProTaper Next X1 > TruNatomy 36 > TruNatomy 26 > TruNatomy 20 (T)
ProTaper Next X1 > ProTaper Next X2 > ProTaper Next X3 > TruNatomy 36 > TruNatomy 26 > TruNatomy 20 (F) |