Optical coherence tomography angiography (OCTA) provides us with a non-invasive and efficient means of imaging anterior and posterior segment vasculature in the eye. OCTA has been shown to be effective in imaging diseases such as diabetic retinopathy, retinal vein occlusions, retinal artery occlusions, ocular ischemic syndrome and neovascularization of the iris. It is especially useful with depth-resolved imaging of the superficial, intermediate, and deep capillary plexi in the retina, which enables us to study and closely monitor disease progression and response to treatment. With further advances in technology, OCTA has the potential to become a more widely used tool in the clinical setting and may even supersede ocular angiography in some areas.