Saliva Sensor: Comparison
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Please note this is a comparison between Version 2 by Vivi Li and Version 1 by Priya Dave.

The United States Centers for Disease Control and Prevention considers saliva contact the lead transmission mean of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19). Saliva droplets or aerosols expelled by sneezing, coughing, breathing, and talking may carry this virus. People in close distance may be exposed directly to these droplets or indirectly when touching the droplets that fall on surrounding surfaces and ending up contracting COVID-19 after touching the mucosa tissue of their faces. It is of great interest to quickly and effectively detect the presence of SARS-CoV-2 in an environment, but the existing methods only work in laboratory settings, to the best of our knowledge. However, it may be possible to detect the presence of saliva in the environment and proceed with prevention measures. However, detecting saliva itself has not been documented in the literature. On the other hand, many sensors that detect different organic components in saliva to monitor a person’s health and diagnose different diseases, ranging from diabetes to dental health, have been proposed and they may be used to detect the presence of saliva.

  • saliva sensor
  • human saliva
  • COVID-19
  • virus detection
  • multi-modal saliva detection
  • droplet detection
  • humidity sensor
  • virus sensor
  • SARS-CoV-2 detection
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References

  1. How COVID-19 Is Changing the World. Available online: https://data.unicef.org/resources/how-covid-19-is-changing-the-world-a-statistical-perspective/ (accessed on 1 November 2020).
  2. Weintraub, K. How Contagious? Likely Before You Know You’re Sick. Available online: https://www.webmd.com/lung/news/20200428/how-contagious-likely-before-you-know-youre-sick (accessed on 1 November 2020).
  3. COVID-19 Overview and Infection Prevention and Control Priorities in Non-US Healthcare Settings. Available online: https://www.cdc.gov/coronavirus/2019-ncov/hcp/non-us-settings/overview/index.html (accessed on 1 November 2020).
  4. CDC Updates COVID-19 Transmission Webpage to Clarify Information about Types of Spread. Available online: https://www.cdc.gov/media/releases/2020/s0522-cdc-updates-covid-transmission.html (accessed on 1 November 2020).
  5. De Almeida, P.D.V.; Gregio, A.; Machado, M.; De Lima, A.; Azevedo, L.R. Saliva composition and functions: A comprehensive review. J. Contemp. Dent. Pr. 2008, 9, 72–80.
  6. Dawes, C. Effects of diet on salivary secretion and composition. J. Dent. Res. 1970, 49, 1263–1272.
  7. Young, J.; Schneyer, C.A. Composition of saliva in mammalia. Aust. J. Exp. Biol. Med. Sci. 1981, 59, 1–53.
  8. Lenander-Lumikari, M.; Loimaranta, V. Saliva and dental caries. Adv. Dent. Res. 2000, 14, 40–47.
  9. Kidd, E.A.; Fejerskov, O. Dental Caries: The Disease and Its Clinical Management; Blackwell Munksgaard: Oxford, UK, 2003.
  10. Castagnola, M.; Picciotti, P.M.; Messana, I.; Fanali, C.; Fiorita, A.; Cabras, T.; Calo, L.; Pisano, E.; Passali, G.C.; Iavarone, F.; et al. Potential applications of human saliva as diagnostic fluid. Acta Otorhinolaryngol. Ital. 2011, 31, 347.
  11. Dawes, C.; Pedersen, A.M.L.; Villa, A.; Ekström, J.; Proctor, G.; Vissink, A.; Aframian, D.; McGowan, R.; Aliko, A.; Narayana, N.; et al. The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI. Arch. Oral Biol. 2015, 60, 863–874.
  12. Hamid, H.; Khurshid, Z.; Adanir, N.; Zafar, M.S.; Zohaib, S. COVID-19 Pandemic and Role of Human Saliva as a Testing Biofluid in Point-of-Care Technology. Eur. J. Dent. 2020.
  13. Coronavirus (COVID-19) Update: FDA Authorizes First Diagnostic Test Using At-Home Collection of Saliva Specimens. Available online: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-diagnostic-test-using-home-collection-saliva (accessed on 1 November 2020).
  14. Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization to Yale School of Public Health for SalivaDirect, Which Uses a New Method of Saliva Sample Processing. Available online: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-issues-emergency-use-authorization-yale-school-public-health (accessed on 1 November 2020).
  15. Akiba, U.; Anzai, J.I. Recent progress in electrochemical biosensors for glycoproteins. Sensors 2016, 16, 2045.
  16. Flanagan, E.P.; Hinson, S.R.; Lennon, V.A.; Fang, B.; Aksamit, A.J.; Morris, P.P.; Basal, E.; Honorat, J.A.; Alfugham, N.B.; Linnoila, J.J.; et al. Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients. Ann. Neurol. 2017, 81, 298–309.
  17. Zheng, J.; Xie, G.; Chen, C. An alpha-Amylase Biosensor with 1, 1-Dimethyl-3-(2-Amino-1-Hydroxyethyl) Ferrocene as an Electron Transfer Mediator. In Proceedings of the 2010 4th International Conference on Bioinformatics and Biomedical Engineering, Chengdu, China, 18–20 June 2010; IEEE: Piscataway, NJ, USA, 2010; pp. 1–5.
  18. Eom, K.S.; Lee, Y.J.; Seo, H.W.; Kang, J.Y.; Shim, J.S.; Lee, S.H. Sensitive and non-invasive cholesterol determination in saliva via optimization of enzyme loading and platinum nano-cluster composition. Analyst 2020, 145, 908–916.
  19. Pasha, S.K.; Kaushik, A.; Vasudev, A.; Snipes, S.A.; Bhansali, S. Electrochemical immunosensing of saliva cortisol. J. Electrochem. Soc. 2013, 161, B3077.
  20. Arya, S.K.; Chornokur, G.; Venugopal, M.; Bhansali, S. Antibody modified gold micro array electrode based electrochemical immunosensor for ultrasensitive detection of cortisol in saliva and ISF. Procedia Eng. 2010, 5, 804–807.
  21. Du, Y.; Zhang, W.; Wang, M.L. Sensing of salivary glucose using nano-structured biosensors. Biosensors 2016, 6, 10.
  22. Arakawa, T.; Kuroki, Y.; Nitta, H.; Chouhan, P.; Toma, K.; Sawada, S.i.; Takeuchi, S.; Sekita, T.; Akiyoshi, K.; Minakuchi, S.; et al. Mouthguard biosensor with telemetry system for monitoring of saliva glucose: A novel cavitas sensor. Biosens. Bioelectron. 2016, 84, 106–111.
  23. Evans, R.D.; Cooke, W.; Hemmila, U.; Calice-Silva, V.; Raimann, J.; Craik, A.; Mandula, C.; Mvula, P.; Msusa, A.; Dreyer, G.; et al. A salivary urea nitrogen dipstick to detect obstetric-related acute kidney disease in Malawi. Kidney Int. Rep. 2018, 3, 178–184.
  24. Agrawal, R.; Sharma, N.; Rathore, M.; Gupta, V.; Jain, S.; Agarwal, V.; Goyal, S. Noninvasive method for glucose level estimation by saliva. J. Diabetes Metab. 2013, 4, 2–5.
  25. Vučićević-Boras, V.; Topić, B.; Cekić-Arambašin, A.; Stavljenić-Rukavina, A.; Zadro, R.; Devčić, T. Measurement of Salivary Peroxidase Values in Unstimulated and Stimulated Whole Saliva in a Dental Student Population. Acta Stomatol. Croat. 2001, 35, 357–359.
  26. Soni, A.; Jha, S.K. Smartphone based non-invasive salivary glucose biosensor. Anal. Chim. Acta 2017, 996, 54–63.
  27. Malon, R.S.; Sadir, S.; Balakrishnan, M.; Córcoles, E.P. Saliva-based biosensors: Noninvasive monitoring tool for clinical diagnostics. BioMed Res. Int. 2014, 2014, 962903.
  28. Du, Y.; Zhang, W.; Wang, M.L. An on-chip disposable salivary glucose sensor for diabetes control. J. Diabetes Sci. Technol. 2016, 10, 1344–1352.
  29. Bruen, D.; Delaney, C.; Florea, L.; Diamond, D. Glucose sensing for diabetes monitoring: Recent developments. Sensors 2017, 17, 1866.
  30. Dominguez, R.B.; Orozco, M.A.; Chávez, G.; Márquez-Lucero, A. The evaluation of a low-cost colorimeter for glucose detection in salivary samples. Sensors 2017, 17, 2495.
  31. Della Ventura, B.; Sakač, N.; Funari, R.; Velotta, R. Flexible immunosensor for the detection of salivary α-amylase in body fluids. Talanta 2017, 174, 52–58.
  32. Kim, D.M.; Moon, J.M.; Lee, W.C.; Yoon, J.H.; Choi, C.S.; Shim, Y.B. A potentiometric non-enzymatic glucose sensor using a molecularly imprinted layer bonded on a conducting polymer. Biosens. Bioelectron. 2017, 91, 276–283.
  33. Santana-Jiménez, L.A.; Márquez-Lucero, A.; Osuna, V.; Estrada-Moreno, I.; Dominguez, R.B. Naked-Eye detection of glucose in saliva with bienzymatic paper-based sensor. Sensors 2018, 18, 1071.
  34. Ahmad, I. Non-Invasive Quantum Dot Based Sensors for the Detection of Glucose and Cholesterol in Saliva. Ph.D. Thesis, University of Liverpool, Liverpool, UK, 2017.
  35. Surendran, V.; Chiulli, T.; Manoharan, S.; Knisley, S.; Packirisamy, M.; Chandrasekaran, A. Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium. Biosensors 2019, 9, 73.
  36. Soni, A.; Jha, S.K. Saliva based noninvasive optical urea biosensor. In Proceedings of the 2017 IEEE Sensors, Glasgow, UK, 29 October–1 November 2017; IEEE: Piscataway, NJ, USA, 2017; pp. 1–3.
  37. Yazid, F.; Zain, M.; Yusof, Z.; Ghazali, F.; Zulkifli, S.; Nadri, N.; Ariffin, S.; Wahab, R. Caries detection analysis in human saliva alpha amylase. In AIP Conference Proceedings; AIP Publishing LLC: Melville, NY, USA, 2020; Volume 2203, p. 020014.
  38. Guha, S.; Ramaker, K.; Krause, T.; Wenger, C. A CMOS radio frequency biosensor for rapid detection and screening of sputum-mucin viscosity. In Proceedings of the 2017 IEEE Sensors, Glasgow, UK, 29 October–1 November 2017; IEEE: Piscataway, NJ, USA, 2017; pp. 1–3.
  39. Soltani Zarrin, P.; Jamal, F.I.; Guha, S.; Wessel, J.; Kissinger, D.; Wenger, C. Design and fabrication of a BiCMOS dielectric sensor for viscosity measurements: A possible solution for early detection of COPD. Biosensors 2018, 8, 78.
  40. Liu, X.; Li, Q.; Gu, P.; Su, S.; Huang, Y.; Feng, X.; Fan, Q.; Huang, W. Highly sensitive fluorometric turn-on detection of lysozyme based on a graphene oxide/ssDNA assembly. IEEE Sens. J. 2017, 17, 5431–5436.
  41. Khan, N.I.; Maddaus, A.G.; Song, E. A low-cost inkjet-printed aptamer-based electrochemical biosensor for the selective detection of lysozyme. Biosensors 2018, 8, 7.
  42. Vasilescu, A.; Wang, Q.; Li, M.; Boukherroub, R.; Szunerits, S. Aptamer-based electrochemical sensing of lysozyme. Chemosensors 2016, 4, 10.
  43. Giuffrida, M.C.; Cigliana, G.; Spoto, G. Ultrasensitive detection of lysozyme in droplet-based microfluidic devices. Biosens. Bioelectron. 2018, 104, 8–14.
  44. Rumenjak, V.; Milardović, S.; Vranić, L.; Kruhak, I.; Rajić, Z. Determination of Electrolyte Concentration in Saliva by Potentiometrie Method. Acta Stomatol. Croat. 1996, 30, 189–195.
  45. Urbanowicz, M.; Pijanowska, D.G.; Jasiński, A.; Ekman, M.; Bocheńska, M.K. A miniaturized solid-contact potentiometric multisensor platform for determination of ionic profiles in human saliva. J. Solid State Electrochem. 2019, 23, 3299–3308.
  46. Soni, A.; Surana, R.K.; Jha, S.K. Smartphone based optical biosensor for the detection of urea in saliva. Sens. Actuators B Chem. 2018, 269, 346–353.
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