Despite the long-term experience in the application of noise walls, the uncertainty in wall panel service life efficiency is almost equal between panels built from established and new materials, which are—because of the desire to increase the sustainability of noise walls—developing at an ever-faster pace. The presented meta-analysis of data collected during a systematic review of concrete, metal, and wood panels’ acoustic and non-acoustic characteristics, long term performance, and cradle-to-gate sustainability aims to reduce this uncertainty and support the process of noise wall design and management by shifting the emphasis in decision making from construction costs to the long-term sustainability of the road traffic noise mitigation project. The multi-criterial analysis showed that when choosing a panel, preference should be given to those using lightweight concrete materials.