Spins in Semiconductor Nanoparticles: Comparison
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Please note this is a comparison between Version 3 by Vladimir Fomin and Version 2 by Vladimir Fomin.

The present overview of spin-dependent phenomena in nonmagnetic semiconductor microparticles (MPs) and nanoparticles (NPs) with interacting nuclear and electron spins is aimed at covering a gap between the basic properties of spin behavior in solid-state systems and a tremendous growth of the experimental results on biomedical applications of those particles. We represent modern achievements of spin-dependent phenomena in the bulk semiconductors from the theory of optical spin orientation under indirect optical injection of carriers and spins in the bulk crystalline silicon (c-Si)—via numerous insightful findings in the realm of characterization and control through the spin polarization—to the design and verification of nuclear spin hyperpolarization in semiconductor MPs and NPs for magnetic resonance imaging (MRI) diagnostics. The electron spin-dependent phenomena in Si-based nanostructures include the photosensitized generation of singlet oxygen in porous Si and design of Si NPs with unpaired electron spins as prospective contrast agents in MRI. The experimental results are analyzed by considering both the quantum mechanical approach and several phenomenological models for the spin behavior in semiconductor/molecular systems. Advancements and perspectives of the biomedical applications of spin-dependent properties of Si NPs for diagnostics and therapy of cancer are discussed.

- Spin-dependent phenomena in semiconductors are analyzed starting from a theory of the dynamic nuclear polarization via numerous insightful findings in the realm of characterization and control through the nuclear spin polarization in nanoparticles and their aggregates into microparticles as potential contrast agents for magnetic resonance imaging (MRI) applications. 

- Electron spin-dependent process of the photosensitized generation of singlet oxygen in porous silicon (Si) for photodynamic therapy application and design of Si-based nanoparticles with electron spin centers for MRI contrasting for cancer theranostics are discussed.

 

  • Si micro-and nanoparticles
  • optically induced dynamic nuclear polarization
  • optical spin orientation
  • nuclear spin hyperpolarization
  • photosensitized generation of singlet oxygen
  • magnetic resonance imaging
  • diagnostics and therapy of cancer
  • micro-and nanoparticles
  • silicon
  • photosensitized generation
  • singlet oxygen
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References

  1. Luu, Q.S.; Kim, J.; Jo, D.; Jeong, J.; Lee, Y. Applications and perspective of silicon particles in hyperpolarized 29Si magnetic resonance imaging. Appl. Spectrosc. Rev. 2020, 55, 476-490, doi:10.1080/05704928.2019.1676255.Fomin, V.M.; Timoshenko, V.Yu. Spin-Dependent Phenomena in Semiconductor Micro- and Nanoparticles—From Fundamentals to Applications, Appl. Sci. 2020, 10, 4992, doi:10.3390/app10144992
  2. Timoshenko, V.Y.Porous Silicon in Photodynamic and Photothermal Therapy. In: Handbook of Porous Silicon, 2nd ed.; Canham, L., Ed.; Springer: Berlin-Heidelberg, Germany, 2018; pp. 1461–1469, doi:10.1007/978-3-319-71381-6_93.Abragam, A.; Goldman, M. Principles of dynamic nuclear polarisation. Rep. Prog. Phys. 1978, 41, 395–467, doi:10.1088/0034-4885/41/3/002.
  3. Kabashin, A.V.; Timoshenko, V.Y. What theranostic applications could ultrapure laser-synthesized Si nanoparticles have in cancer? Nanomedicine 2016, 11, 2247–2250, doi:10.2217/nnm-2016-0228.Kwiatkowski, G.; Polyhach, Y.; Jähnig, F.; Shiroka, T.; Starsich, F.H.L.; Ernst, M.; Kozerke, S. Exploiting Endogenous Surface Defects for Dynamic Nuclear Polarization of Silicon Micro- and Nanoparticles. J. Phys. Chem. C 2018, 122, 25668–25680, doi:10.1021/acs.jpcc.8b08926.
  4. Zinovieva, A.F.; Nikiforov, A.I.; Timofeev, V.A.; Nenashev, A.V.; Dvurechenskii, A.V.; Kulik, L.V. Electron localization in Ge/Si heterostructures with double quantum dots detected by an electron spin resonance method. Phys. Rev. B 2013, 88, 235308, 1-8, doi:10.1103/physrevb.88.235308.Lampel, G. Nuclear Dynamic Polarization by Optical Electronic Saturation and Optical Pumping in Semiconductors. Phys. Rev. Lett. 1968, 20, 491–493, doi:10.1103/physrevlett.20.491.
  5. Lipps, F.; Pezzoli, F.; Stoffel, M.; Deneke, C.; Thomas, J.; Rastelli, A.; Kataev, V.; Schmidt, O.G.; Büchner, B. Electron spin resonance study of Si/SiGe quantum dots. Phys. Rev. B 2010, 81, 125312, 1-9, doi:10.1103/physrevb.81.125312.Overhauser, A.W. Polarization of Nuclei in Metals. Phys. Rev. 1953, 92, 411–415, doi:10.1103/physrev.92.411.
  6. Giorgioni, A.; Paleari, S.; Cecchi, S.; Vitiello, E.; Grilli, E.; Isella, G.; Jantsch, W.; Fanciulli, M.; Pezzoli, F. Strong confinement-induced engineering of the g factor and lifetime of conduction electron spins in Ge quantum wells. Nat. Commun. 2016, 7, 13886, 1–11. Available online: https://www.nature.com/articles/ncomms13886 (accessed on July 17, 2020)..Dyakonov, M.I.; Perel, V.I. Theory of Optical Spin Orientation of Electrons and Nuclei in Semiconductors. In: Optical Orientation; Meier, F., Zakharchenya, B.P., Eds.; Elsevier: Amsterdam, The Netherlands, 1984, doi:10.1016/B978-0-444-86741-4.50007-X.
  7. Khaetskii, A.V.; Nazarov, Y.V. Spin-flip transitions between Zeeman sublevels in semiconductor quantum dots. Phys. Rev. B 2001, 64, 125316, 16, doi:10.1103/physrevb.64.125316.Abragam, A. The Principles of Nuclear Magnetism; Oxford University Press: Oxford, UK, 1961.
  8. Alcalde, A.M.; Marques, G.E. Electron spin-phonon relaxation in quantum dots. Braz. J. Phys. 2004, 34, 705707. Available online: http://www.sbfisica.org.br/bjp/files/v34_705.pdf (accessed on July 17, 2020).Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Optical orientation of 29Si nuclei in n-type silicon and its dependence on the pumping light intensity. Sov. Phys. JETP 1976, 44, 500–504
  9. Abragam, A.; Goldman, M. Principles of dynamic nuclear polarisation. Rep. Prog. Phys. 1978, 41, 395–467, doi:10.1088/0034-4885/41/3/002.Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Influence of the depth of location of donor levels on the degree of optical orientation of 29Si nuclei in silicon. Sov. Phys. JETP Lett. 1976, 24, 366368.
  10. Kwiatkowski, G.; Polyhach, Y.; Jähnig, F.; Shiroka, T.; Starsich, F.H.L.; Ernst, M.; Kozerke, S. Exploiting Endogenous Surface Defects for Dynamic Nuclear Polarization of Silicon Micro- and Nanoparticles. J. Phys. Chem. C 2018, 122, 25668–25680, doi:10.1021/acs.jpcc.8b08926.Ekimov, A.I.; Safarov, V.I. Optical detection of dynamic polarization of nuclei in semiconductors. JETP Lett. 1972, 15, 179181
  11. Aptekar, J.W.; Cassidy, M.C.; Johnson, A.C.; Barton, R.A.; Lee, M.; Ogier, A.C.; Vo, C.; Anahtar, M.N.; Ren, Y.; Bhatia, S.N.; et al. Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents. ACS Nano 2009, 3, 4003–4008, doi:10.1021/nn900996p.Tycko, R. Optical pumping in indium phosphide: 31P NMR measurements and potential for signal enhancement in biological solid state NMR. Solid State Nucl. Magn. Reson. 1998, 11, 1–9.
  12. Abragam, A. The Principles of Nuclear Magnetism; Oxford University Press: Oxford, UK, 1961.Pietraß, T.; Tomaselli, M. Optically pumped NMR in CdS single crystals. Phys. Rev. B 1999, 59, 1986–1989, doi:10.1103/physrevb.59.1986.
  13. Jansen, R. Silicon spintronics. Nat. Mater. 2012, 11, 400–408, doi:10.1038/nmat3293.Zucchetti, C.; Bottegoni, F.; Isella, G.; Finazzi, M.; Rortais, F.; Vergnaud, C.; Widiez, J.; Jamet, M.; Ciccacci, F. Spin-to-charge conversion for hot photoexcited electrons in germanium. Phys. Rev. B 2018, 97, 17, doi:10.1103/PhysRevB.97.125203.
  14. Lampel, G. Nuclear Dynamic Polarization by Optical Electronic Saturation and Optical Pumping in Semiconductors. Phys. Rev. Lett. 1968, 20, 491–493, doi:10.1103/physrevlett.20.491.De Cesari, S.; Balocchi, A.; Vitiello, E.; Jahandar, P.; Grilli, E.; Amand, T.; Marie, X.; Myronov, M.; Pezzoli, F. Spin-coherent dynamics and carrier lifetime in strained Ge1−xSnx semiconductors on silicon. Phys. Rev. B 2019, 99, 1–9, doi:10.1103/physrevb.99.035202.
  15. Lampel, G. Relaxation Nucléaire dans le Silicium à 77°K et Polarisation Dynamique par Pompage Optique. Ph.D. Thesis, Faculte des Sciences de l'Université de Paris a Orsay pour obtenir le grade de Docteur-ès-Sciences Physiques, Université de Paris, Paris, France, 1968.Fujiwara, T.; Ramamoorthy, A. How far can the sensitivity of NMR be increased? Annu. Rep. NMR Spectrosc. 2006, 58, 155–175, doi:10-1016/S0066-4013(05)58003-7.
  16. Overhauser, A.W. Polarization of Nuclei in Metals. Phys. Rev. 1953, 92, 411–415, doi:10.1103/physrev.92.411.Atkins, T.M.; Cassidy, M.C.; Lee, M.; Ganguly, S.; Marcus, C.M.; Kauzlarich, S.M. Synthesis of Long T1 Silicon Nanoparticles for Hyperpolarized 29Si Magnetic Resonance Imaging. ACS Nano 2013, 7, 1609–1617, doi:10.1021/nn305462y.
  17. Kittel, C. Introduction to Solid State Physics; John Wiley & Sons: New York, NY, USA, 1996.Aptekar, J.W.; Cassidy, M.C.; Johnson, A.C.; Barton, R.A.; Lee, M.; Ogier, A.C.; Vo, C.; Anahtar, M.N.; Ren, Y.; Bhatia, S.N.; et al. Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents. ACS Nano 2009, 3, 4003–4008, doi:10.1021/nn900996p.
  18. Shulman, R.G.; Wyluda, B.J. Nuclear magnetic resonance of 29Si in n- and p-type silicon. Phys. Rev. 1956, 103, 11271129, doi:10.1103/PhysRev.103.1127.
  19. Bloembergen, N. Nuclear magnetic relaxation in semiconductors. Physica 1954, 20, 1130–1133, doi:10.1016/s0031-8914(54)80253-9.Casabianca, L.B.; Shames, A.I.; Panich, A.M.; Shenderova, O.; Frydman, L. Factors Affecting DNP NMR in Polycrystalline Diamond Samples. J. Phys. Chem. C 2011, 115, 19041–19048, doi:10.1021/jp206167j.
  20. Lee, M.; Cassidy, M.C.; Ramanathan, C.; Marcus, C.M. Decay of nuclear hyperpolarization in silicon microparticles. Phys. Rev. B 2011, 84, 035304, doi:10.1103/physrevb.84.035304.Dementyev, A.E.; Cory, D.G.; Ramanathan, C. Dynamic Nuclear Polarization in Silicon Microparticles. Phys. Rev. Lett. 2008, 100, 1–4, doi:10.1103/physrevlett.100.127601.
  21. Dyakonov, M.I.; Perel, V.I. Theory of Optical Spin Orientation of Electrons and Nuclei in Semiconductors. In: Optical Orientation; Meier, F., Zakharchenya, B.P., Eds.; Elsevier: Amsterdam, The Netherlands, 1984, doi:10.1016/B978-0-444-86741-4.50007-X.Cassidy, M.C.; Chan, H.R.; Ross, B.D.; Bhattacharya, P.K.; Marcus, C.M. In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat. Nanotechnol. 2013, 8, 363–368, doi:10.1038/nnano.2013.65.
  22. Chekhovich, E.A.; Glazov, M.M.; Krysa, A.; Hopkinson, M.; Senellart, P.; Lemaître, A.; Skolnick, M.S.; Tartakovskii, A.I. Element-sensitive measurement of the hole–nuclear spin interaction in quantum dots. Nat. Phys. 2012, 9, 74–78, doi:10.1038/nphys2514.Lee, M.; Cassidy, M.C.; Ramanathan, C.; Marcus, C.M. Decay of nuclear hyperpolarization in silicon microparticles. Phys. Rev. B 2011, 84, 035304, doi:10.1103/physrevb.84.035304.
  23. Overhauser, A.W. Paramagnetic Relaxation in Metals. Phys. Rev. 1953, 89, 689–700, doi:10.1103/physrev.89.689.Kwiatkowski, G.; Jähnig, F.; Steinhauser, J.; Wespi, P.; Ernst, M.; Kozerke, S. Nanometer size silicon particles for hyperpolarized MRI. Sci. Rep. 2017, 7, 1–6; https://www.nature.com/articles/s41598-017-08709-0.
  24. Li, P.; Dery, H. Theory of Spin-Dependent Phonon-Assisted Optical Transitions in Silicon. Phys. Rev. Lett. 2010, 105, 1–4, doi:10.1103/physrevlett.105.037204.Kovalev, D.; Gross, E.; Künzner, N.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Resonant Electronic Energy Transfer from Excitons Confined in Silicon Nanocrystals to Oxygen Molecules. Phys. Rev. Lett. 2002, 89, 1–4, doi:10.1103/physrevlett.89.137401.
  25. Cassidy, M.C.; Chan, H.R.; Ross, B.D.; Bhattacharya, P.K.; Marcus, C.M. In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat. Nanotechnol. 2013, 8, 363–368, doi:10.1038/nnano.2013.65.Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Spectrally resolved electronic energy transfer from silicon nanocrystals to molecular oxygen mediated by direct electron exchange. Phys. Rev. B 2003, 68, 1–11, doi:10.1103/physrevb.68.115405.
  26. Atkins, T.M.; Cassidy, M.C.; Lee, M.; Ganguly, S.; Marcus, C.M.; Kauzlarich, S.M. Synthesis of Long T1 Silicon Nanoparticles for Hyperpolarized 29Si Magnetic Resonance Imaging. ACS Nano 2013, 7, 1609–1617, doi:10.1021/nn305462y.Fujii, M.; Kovalev, D.; Goller, B.D.; Minobe, S.; Hayashi, S.; Timoshenko, V.Y. Time-resolved photoluminescence studies of the energy transfer from excitons confined in Si nanocrystals to oxygen molecules. Phys. Rev. B 2005, 72, 165321, doi:10.1103/physrevb.72.165321.
  27. Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Optical orientation of Si29 nuclei in n-type silicon and its dependence on the pumping light intensity. Sov. Phys. JETP 1976, 44, 500–504Timoshenko, V.Y.; Kudryavtsev, A.A.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Belogorokhov, I.A.; Kovalev, D.; Kashkarov, P.K. Silicon nanocrystals as photosensitizers of active oxygen for biomedical applications. JETP Lett. 2006, 83, 423–426, doi:10.1134/s0021364006090128.
  28. Bagraev, N.T.; Vlasenko, L.S.; Zhitnikov, R.A. Influence of the depth of location of donor levels on the degree of optical orientation of 29Si nuclei in silicon. Sov. Phys. JETP Lett. 1976, 24, 366368.Timoshenko, V.Y.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Gongalsky, M.; Efimova, A.I.; Konstantinova, E.A.; Bazylenko, T.Y.; Kashkarov, P.K.; Kudriavtsev, A.A. Silicon nanocrystals as efficient photosensitizer of singlet oxygen for biomedical applications. SPIE Proc. 2007, 6606, 66061E, doi:10.1117/12.729523.
  29. Verhulst, A.S.; Rau, I.G.; Yamamoto, Y.; Itoh, K.M. Optical pumping of Si29 nuclear spins in bulk silicon at high magnetic field and liquid helium temperature. Phys. Rev. B 2005, 71, 1–10, doi:10.1103/physrevb.71.235206.Xiao, L.; Gu, L.; Howell, S.B.; Sailor, M. Porous Silicon Nanoparticle Photosensitizers for Singlet Oxygen and Their Phototoxicity against Cancer Cells. ACS Nano 2011, 5, 3651–3659, doi:10.1021/nn1035262.
  30. Ekimov, A.I.; Safarov, V.I. Optical detection of dynamic polarization of nuclei in semiconductors. JETP Lett. 1972, 15, 179-181.Osminkina, L.; Tamarov, K.P.; Sviridov, A.P.; Galkin, R.A.; Gongalsky, M.B.; Solovyev, V.V.; Kudryavtsev, A.A.; Timoshenko, V.Y. Photoluminescent biocompatible silicon nanoparticles for cancer theranostic applications. J. Biophotonics 2012, 5, 529–535, doi:10.1002/jbio.201100112.
  31. Tycko, R. Optical pumping in indium phosphide: 31P NMR measurements and potential for signal enhancement in biological solid state NMR. Solid State Nucl. Magn. Reson. 1998, 11, 1–9.Timoshenko, V.Y. Porous Silicon in Photodynamic and Photothermal Therapy. In: Handbook of Porous Silicon, 2nd ed.; Canham, L., Ed.; Springer: BerlinHeidelberg, Germany, 2018; pp. 1461–1469, doi:10.1007/978-3-319-71381-6_93.
  32. Pietraß, T.; Tomaselli, M. Optically pumped NMR in CdS single crystals. Phys. Rev. B 1999, 59, 1986–1989, doi:10.1103/physrevb.59.1986.Kabashin, A.V.; Timoshenko, V.Y. What theranostic applications could ultrapure laser-synthesized Si nanoparticles have in cancer? Nanomedicine 2016, 11, 2247–2250, doi:10.2217/nnm-2016-0228.
  33. Cheng, J.L.; Rioux, J.; Fabian, J.; Sipe, J.E. Theory of optical spin orientation in silicon. Phys. Rev. B 2011, 83, 1–15, doi:10.1103/physrevb.83.165211.Gongalsky, M.B.; Kargina, Y.V.; Osminkina, L.; Perepukhov, A.M.; Gulyaev, M.; Vasiliev, A.; Pirogov, Y.A.; Maximychev, A.V.; Timoshenko, V.Y. Porous silicon nanoparticles as biocompatible contrast agents for magnetic resonance imaging. Appl. Phys. Lett. 2015, 107, 233702, doi:10.1063/1.4937731.
  34. Cheng, J.L.; Rioux, J.; Sipe, J.E. Two-photon indirect optical injection and two-color coherent control in bulk silicon. Phys. Rev. B 2011, 84, 1–13, doi:10.1103/physrevb.84.235204.Kargina, Y.V.; Gongalsky, M.B.; Perepukhov, A.M.; Gippius, A.A.; Minnekhanov, A.A.; Zvereva, E.A.; Maximychev, A.V.; Timoshenko, V.Y. Investigation of proton spin relaxation in water with dispersed silicon nanoparticles for potential magnetic resonance imaging applications. J. Appl. Phys. 2018, 123, 1–6, doi:10.1063/1.5006846.
  35. Guite, C.; Venkataraman, V. Measurement of Electron Spin Lifetime and Optical Orientation Efficiency in Germanium Using Electrical Detection of Radio Frequency Modulated Spin Polarization. Phys. Rev. Lett. 2011, 107, 1–4, doi:10.1103/physrevlett.107.166603.Cullis, A.G.; Canham, L.T.; Calcott, P.D.J. The structural and luminescence properties of porous silicon. J. Appl. Phys. 1997, 82, 909–965, doi:10.1063/1.366536.
  36. Pezzoli, F.; Bottegoni, F.; Trivedi, D.; Ciccacci, F.; Giorgioni, A.; Li, P.; Cecchi, S.; Grilli, E.; Song, Y.; Guzzi, M.; et al. Optical Spin Injection and Spin Lifetime in Ge Heterostructures. Phys. Rev. Lett. 2012, 108, 1–5, doi:10.1103/physrevlett.108.156603.Rohrer, M.; Bauer, H.; Mintorovitch, J.; Requardt, M.; Weinmann, H.-J. Comparison of Magnetic Properties of MRI Contrast Media Solutions at Different Magnetic Field Strengths. Investig. Radiol. 2005, 40, 715–724, doi:10.1097/01.rli.0000184756.66360.d3.
  37. Giorgioni, A.; Vitiello, E.; Grilli, E.; Guzzi, M.; Pezzoli, F. Valley-dependent spin polarization and long-lived electron spins in germanium. Appl. Phys. Lett. 2014, 105, 152404, doi:10.1063/1.4898078.Araki, K.; Uchiyama, M.K.; Toma, S.; Rodrigues, S.F.; Shimada, A.L.B.; Loiola, R.A.; Rodríguez, H.J.C.; Oliveira, P.V.; Luz, M.S.; Rabbani, S.R.; et al. Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool. Int. J. Nanomed. 2015, 10, 4731–4746, doi:10.2147/IJN.S83150.
  38. Li, P.; Trivedi, D.; Dery, H. Spin-dependent optical properties in strained silicon and germanium. Phys. Rev. B 2013, 87, 1–15, doi:10.1103/physrevb.87.115203.Kargina, Y.V.; Perepukhov, A.M.; Kharin, A.Y.; Zvereva, E.A.; Koshelev, A.V.; Zinovyev, S.V.; Maximychev, A.V.; Alykova, A.F.; Sharonova, N.V.; Zubov, V.P.; et al. Silicon Nanoparticles Prepared by Plasma‐Assisted Ablative Synthesis: Physical Properties and Potential Biomedical Applications. Phys. Status Solidi A 2019, 216, 1800897, doi:10.1002/pssa.201800897.
  39. Liu, Z.; Nestoklon, M.O.; Cheng, J.L.; Ivchenko, E.L.; Wu, M.W. Spin-dependent intravalley and intervalley electron–phonon scatterings in germanium. Phys. Solid State 2013, 55, 1619–1734, doi:10.1134/S1063783413080167.Kargina, Y.V.; Zinovyev, S.V.; Perepukhov, A.M.; Suslova, E.V.; Ischenko, A.A.; Timoshenko, V.Y. Silicon nanoparticles with iron impurities for multifunctional applications. Funct. Mater. Lett. 2020, 13, 2040007, doi:10.1142/s179360472040007x.
  40. Sircar, N.; Bougeard, D. Experimental investigation of the optical spin-selection rules in bulk Si and Ge/Si quantum dots. Phys. Rev. B 2014, 89, 1–5, doi:10.1103/physrevb.89.041301.Bouchoucha, M.; Van Heeswijk, R.B.; Gossuin, Y.; Kleitz, F.; Fortin, M.-A. Fluorinated Mesoporous Silica Nanoparticles for Binuclear Probes in 1H and 19F Magnetic Resonance Imaging. Langmuir 2017, 33, 10531–10542, doi:10.1021/acs.langmuir.7b01792.
  41. Akimoto, I.; Naka, N. Two optical routes of cold carrier injection in silicon revealed by time-resolved excitation spectroscopy. Appl. Phys. Express 2017, 10, 1-4, doi:10.7567/APEX.10.061301.
  42. Bottegoni, F.; Zucchetti, C.; Ciccacci, F.; Finazzi, M.; Isella, G. Optical generation of pure spin currents at the indirect gap of bulk Si. Appl. Phys. Lett. 2017, 110, 1–5, doi:10.1063/1.4974820.
  43. Cushing, S.K.; Zürch, M.; Kraus, P.M.; Carneiro, L.M.; Lee, A.; Chang, H.-T.; Kaplan, C.J.; Leone, S.R. Hot phonon and carrier relaxation in Si(100) determined by transient extreme ultraviolet spectroscopy. Struct. Dyn. 2018, 5, 1–20, doi:10.1063/1.5038015.
  44. Zucchetti, C.; Bottegoni, F.; Isella, G.; Finazzi, M.; Rortais, F.; Vergnaud, C.; Widiez, J.; Jamet, M.; Ciccacci, F. Spin-to-charge conversion for hot photoexcited electrons in germanium. Phys. Rev. B 2018, 97, 1-7, doi:10.1103/PhysRevB.97.125203.
  45. De Cesari, S.; Balocchi, A.; Vitiello, E.; Jahandar, P.; Grilli, E.; Amand, T.; Marie, X.; Myronov, M.; Pezzoli, F. Spin-coherent dynamics and carrier lifetime in strained Ge1−xSnx semiconductors on silicon. Phys. Rev. B 2019, 99, 1–9, doi:10.1103/physrevb.99.035202.
  46. Ardenkjaer-Larsen, J.H.; Fridlund, B.; Gram, A.; Hansson, G.; Lennart Hansson, L.; Lerche, M.H.; Servin, R.; Thaning, M.; Golman, K. Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc. Natl. Acad. Sci. USA 2003, 100, 10158–10163, doi:10.1073/pnas.1733835100.
  47. Fujiwara, T.; Ramamoorthy, A. 2006. How far can the sensitivity of NMR be increased? Annu. Rep. NMR Spectrosc. 2006, 58, 155–175, doi:10-1016/S0066-4013(05)58003-7.
  48. Van Kesteren, H.W.; Wenckebach, W.T.; Schmidt, J. Production of High, Long-Lasting, Dynamic Proton Polarization by Way of Photoexcited Triplet States. Phys. Rev. Lett. 1985, 55, 1642–1644, doi:10.1103/physrevlett.55.1642.
  49. Lelli, M.; Gajan, D.; Lesage, A.; Caporini, M.A.; Vitzthum, V.; Miéville, P.; Héroguel, F.; Rascón, F.; Roussey, A.; Thieuleux, C.; et al. Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface-Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization. J. Am. Chem. Soc. 2011, 133, 2104–2107, doi:10.1021/ja110791d.
  50. Casabianca, L.B.; Shames, A.I.; Panich, A.M.; Shenderova, O.; Frydman, L. Factors Affecting DNP NMR in Polycrystalline Diamond Samples. J. Phys. Chem. C 2011, 115, 19041–19048, doi:10.1021/jp206167j.
  51. Dementyev, A.E.; Cory, D.G.; Ramanathan, C. Dynamic Nuclear Polarization in Silicon Microparticles. Phys. Rev. Lett. 2008, 100, 1–4, doi:10.1103/physrevlett.100.127601.
  52. Kwiatkowski, G.; Jähnig, F.; Steinhauser, J.; Wespi, P.; Ernst, M.; Kozerke, S. Nanometer size silicon particles for hyperpolarized MRI. Sci. Rep. 2017, 7, 1–6. Available online: https://www.nature.com/articles/s41598-017-08709-0 (accessed on July 17, 2020).
  53. Whiting, N.; Hu, J.; Shah, J.V.; Cassidy, M.C.; Cressman, E.; Millward, S.W.; Menter, D.G.; Marcus, C.M.; Bhattacharya, P.K. Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles. Sci. Rep. 2015, 5, 1–8, doi:10.1038/srep12842.
  54. Whiting, N.; Hu, J.; Zacharias, N.M.; Lokesh, G.L.; Volk, D.E.; Menter, D.G.; Rupaimoole, R.; Previs, R.; Sood, A.K.; Bhattacharya, P. Developing hyperpolarized silicon particles for In Vivo MRI targeting of ovarian cancer. J. Med. Imaging 2016, 3, 1–9, doi:10.1117/1.JMI.3.3.036001.
  55. Seo, H.; Choi, I.; Whiting, N.; Hu, J.; Luu, Q.S.; Pudakalakatti, S.; McCowan, C.; Kim, Y.; Zacharias, N.; Lee, Y.; et al. Hyperpolarized Porous Silicon Nanoparticles: Potential Theragnostic Material for 29Si Magnetic Resonance Imaging. ChemPhysChem 2018, 19, 2143–2147, doi:10.1002/cphc.201800461.
  56. Hu, J.; Whiting, N.; Bhattacharya, P.K. Hyperpolarization of Silicon Nanoparticles with TEMPO Radicals. J. Phys. Chem. C 2018, 122, 10575–10581, doi:10.1021/acs.jpcc.8b00911.
  57. Sanders, G.D.; Chang, Y.-C. Theory of optical properties of quantum wires in porous silicon. Phys. Rev. B 1992, 45, 9202–9213, doi:10.1103/physrevb.45.9202.
  58. Delley, B.; Steigmeier, E.F. Size dependence of band gaps in silicon nanostructures. Appl. Phys. Lett. 1995, 67, 2370–2372, doi:10.1063/1.114348.
  59. John, G.J.; Singh, V.A. Porous silicon: Theoretical studies. Phys. Rep. 1995, 263, 93–151, doi:10.1016/0370-1573(95)00052-4.
  60. Calcott, P.D.J.; Nash, K.J.; Canham, L.T.; Kane, M.J.; Brumhead, D. Identification of radiative transitions in highly porous silicon. J. Phys. Condens. Matter 1993, 5, L91–L98, doi:10.1088/0953-8984/5/7/003.
  61. Kovalev, D.; Heckler, H.; Polisski, G.; Koch, F. Optical Properties of Si Nanocrystals. Phys. Status Solidi B 1999, 215, 871–932, doi:10.1002/(sici)1521-3951(199910)215:23.0.co;2-9.
  62. Bisi, O.; Ossicini, S.; Pavesi, L. Porous silicon: A quantum sponge structure for silicon based optoelectronics. Surf. Sci. Rep. 2000, 38, 1–126, doi:10.1016/s0167-5729(99)00012-6.
  63. Moser, J.G. Photodynamic Tumor Therapy: 2nd and 3rd Generation Photosensitizers; Harwood Academic Publushers: Amsterdam, The Netherlands, 1998.
  64. Kovalev, D.; Gross, E.; Künzner, N.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Resonant Electronic Energy Transfer from Excitons Confined in Silicon Nanocrystals to Oxygen Molecules. Phys. Rev. Lett. 2002, 89, 1–4, doi:10.1103/physrevlett.89.137401.
  65. Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Koch, F.; Timoshenko, V.Y.; Fujii, M. Spectrally resolved electronic energy transfer from silicon nanocrystals to molecular oxygen mediated by direct electron exchange. Phys. Rev. B 2003, 68, 1–11, doi:10.1103/physrevb.68.115405.
  66. Turro, N.J. Modern Molecular Photochemistry; University Science Books: Mill Valley, CA, USA, 1991.
  67. Kearns, D.R. Physical and chemical properties of singlet molecular oxygen. Chem. Rev. 1971, 71, 395–427, doi:10.1021/cr60272a004.
  68. Arnold, S.J.; Kubo, M.; Ogryzlo, E.A. Relaxation and Reactivity of Singlet Oxygen. Adv. Chem. 1968, 77, 133–142, doi:10.1021/ba-1968-0077.ch070.
  69. Krasnovsky, A.A.; Kubo, M.; Ogryzlo, A. Singlet molecular oxygen in photobiochemical systems: IR phosphorescence studies, Membr. Cell Biol. 1998, 12, 665–690.
  70. Fujii, M.; Minobe, S.; Usui, M.; Hayashi, Sh.; Gross, E.; Diener, J., Kovalev, D. Singlet oxygen formation by porous Si in solution. Phys. Rev. B 2004, 70, 085311, doi:1103/PhysRevB.70.085311.
  71. Kovalev, D.; Fujii, M. Silicon Nanocrystals: Photosensitizers for Oxygen Molecules. Adv. Mater. 2005, 17, 2531–2544, doi:10.1002/adma.200500328.
  72. Chirvony, V.; Bolotin, V.; Matveeva, E.; Parkhutik, V. Fluorescence and 1O2 generation properties of porphyrin molecules immobilized in oxidized nano-porous silicon matrix. J. Photochem. Photobiol. A Chem. 2006, 181, 106–113, doi:10.1016/j.jphotochem.2005.11.008.
  73. Gongalsky, M.; Konstantinova, E.A.; Osminkina, L.; Timoshenko, V.Y. Detection of singlet oxygen in photoexcited porous silicon nanocrystals by photoluminescence measurements. Semiconductors 2010, 44, 89–92, doi:10.1134/s106378261001015x.
  74. Konstantinova, E.A.; Demin, V.A.; Timoshenko, V.Y.; Kashkarov, P.K. EPR diagnostics of the photosensitized generation of singlet oxygen on the surface of silicon nanocrystals. JETP Lett. 2007, 85, 59–62, doi:10.1134/s0021364007010122.
  75. Konstantinova, E.A.; Demin, V.A.; Timoshenko, V.Y. Investigation of the generation of singlet oxygen in ensembles of photoexcited silicon nanocrystals by electron paramagnetic resonance spectroscopy. J. Exp. Theor. Phys. 2008, 107, 473–481, doi:10.1134/s1063776108090148.
  76. Fujii, M.; Usui, M.; Hayashi, S.; Gross, E.; Kovalev, D.; Künzner, N.; Diener, J.; Timoshenko, V.Y. Singlet oxygen formation by porous Si in solution. Phys. Status Solidi A 2005, 202, 1385–1389, doi:10.1002/pssa.200461107.
  77. Cullis, A.G.; Canham, L.T.; Calcott, P.D.J. The structural and luminescence properties of porous silicon. J. Appl. Phys. 1997, 82, 909–965, doi:10.1063/1.366536.
  78. Dexter, D.L. A Theory of Sensitized Luminescence in Solids. J. Chem. Phys. 1953, 21, 836, doi:10.1063/1.1699044.
  79. Palenov, D.A.; Zhigunov, D.M.; Shalygina, O.A.; Kashkarov, P.K.; Timoshenko, V.Y. Specific features of dissipation of electronic excitation energy in coupled molecular solid systems based on silicon nanocrystals on intense optical pumping. Semiconductors 2007, 41, 1351–1355, doi:10.1134/s1063782607110140.
  80. Delerue, C.; Lannoo, M.; Allan, G.; Martin, E.; Mihalcescu, I.; Vial, J.C.; Romestain, R.; Muller, F.; Bsiesy, A. Auger and Coulomb Charging Effects in Semiconductor Nanocrystallites. Phys. Rev. Lett. 1995, 75, 2228–2231, doi:10.1103/PhysRevLett.75.2228.
  81. Kovalev, D.; Gross, E.; Diener, J.; Timoshenko, V.Y.; Fujii, M. Photodegradation of porous silicon induced by photogenerated singlet oxygen molecules. Appl. Phys. Lett. 2004, 85, 3590, doi:10.1063/1.1804241.
  82. Langmuir, I. The constitution and fundamental properties of solids and liquids. Part I. Solids. J. Am. Chem. Soc. 1916, 38, 2221–2295, doi:10.1021/ja02268a002.
  83. Ryabchikov, Y.V.; Belogorokhov, I.A.; Vorontsov, A.S.; Osminkina, L.; Timoshenko, V.Y.; Kashkarov, P.K. Dependence of the singlet oxygen photosensitization efficiency on morphology of porous silicon. Phys. Status Solidi A 2007, 204, 1271–1275, doi:10.1002/pssa.200674306.
  84. Konstantinova, E.; Demin, V.; Vorontzov, A.; Ryabchikov, Y.V.; Belogorokhov, I.; Osminkina, L.; Forsh, P.; Kashkarov, P.; Timoshenko, V.Y. Electron-paramagnetic resonance and photoluminescence study of Si nanocrystals-photosensitizers of singlet oxygen molecules. J. Non Cryst. Solids 2006, 352, 1156–1159, doi:10.1016/j.jnoncrysol.2005.12.017.
  85. Cantin, J.L.; Schoisswohl, M.; Van Bardeleben, H.J.; Zoubir, N.H.; Vergnat, M. Electron-paramagnetic-resonance study of the microscopic structure of the Si(001)-SiO2 interface. Phys. Rev. B 1995, 52, R11599–R11602, doi:10.1103/physrevb.52.r11599.
  86. Rioux, D.; Laferrière, M.; Douplik, A.; Shah, D.; Lilge, L.; Kabashin, A.V.; Meunier, M.M. Silicon nanoparticles produced by femtosecond laser ablation in water as novel contamination-free photosensitizers. J. Biomed. Opt. 2009, 14, 1–4, doi:10.1117/1.3086608.
  87. Timoshenko, V.Y.; Kudryavtsev, A.A.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Belogorokhov, I.A.; Kovalev, D.; Kashkarov, P.K. Silicon nanocrystals as photosensitizers of active oxygen for biomedical applications. JETP Lett. 2006, 83, 423–426, doi:10.1134/s0021364006090128.
  88. Timoshenko, V.Y.; Osminkina, L.; Vorontsov, A.S.; Ryabchikov, Y.V.; Gongalsky, M.; Efimova, A.I.; Konstantinova, E.A.; Bazylenko, T.Y.; Kashkarov, P.K.; Kudriavtsev, A.A. Silicon nanocrystals as efficient photosensitizer of singlet oxygen for biomedical applications. SPIE Proc. 2007, 6606, 66061E, doi:10.1117/12.729523.
  89. Xiao, L.; Gu, L.; Howell, S.B.; Sailor, M. Porous Silicon Nanoparticle Photosensitizers for Singlet Oxygen and Their Phototoxicity against Cancer Cells. ACS Nano 2011, 5, 3651–3659, doi:10.1021/nn1035262.
  90. Osminkina, L.; Tamarov, K.P.; Sviridov, A.P.; Galkin, R.A.; Gongalsky, M.B.; Solovyev, V.V.; Kudryavtsev, A.A.; Timoshenko, V.Y. Photoluminescent biocompatible silicon nanoparticles for cancer theranostic applications. J. Biophotonics 2012, 5, 529–535, doi:10.1002/jbio.201100112.
  91. Fujii, M.; Kovalev, D.; Goller, B.D.; Minobe, S.; Hayashi, S.; Timoshenko, V.Y. Time-resolved photoluminescence studies of the energy transfer from excitons confined in Si nanocrystals to oxygen molecules. Phys. Rev. B 2005, 72, 165321, doi:10.1103/physrevb.72.165321.
  92. Canham, L.T. Nanoscale semiconducting silicon as a nutritional food additive. Nanotechnology 2007, 18, 185704, doi:10.1088/0957-4484/18/18/185704.
  93. Park, J.-H.; Gu, L.; Von Maltzahn, G.; Ruoslahti, E.; Bhatia, S.N.; Sailor, M.J. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nat. Mater. 2009, 8, 331–336, doi:10.1038/nmat2398.
  94. Dolmans, D.E.J.G.J.; Fukumura, D.; Jain, R.K. Photodynamic therapy for cancer. Nat. Rev. Cancer 2003, 3, 380–387, doi:10.1038/nrc1071.
  95. Gongalsky, M.B.; Kargina, Y.V.; Osminkina, L.; Perepukhov, A.M.; Gulyaev, M.; Vasiliev, A.; Pirogov, Y.A.; Maximychev, A.V.; Timoshenko, V.Y. Porous silicon nanoparticles as biocompatible contrast agents for magnetic resonance imaging. Appl. Phys. Lett. 2015, 107, 233702, doi:10.1063/1.4937731.
  96. Kargina, Y.V.; Gongalsky, M.B.; Perepukhov, A.M.; Gippius, A.A.; Minnekhanov, A.A.; Zvereva, E.A.; Maximychev, A.V.; Timoshenko, V.Y. Investigation of proton spin relaxation in water with dispersed silicon nanoparticles for potential magnetic resonance imaging applications. J. Appl. Phys. 2018, 123, 1–6, doi:10.1063/1.5006846.
  97. Von Bardeleben, H.J.; Stiévenard, D.; Grosman, A.; Ortega, C.; Siejka, J. Defects in porous p-type Si: An electron-paramagnetic-resonance study. Phys. Rev. B 1993, 47, 10899–10902, doi:10.1103/physrevb.47.10899.
  98. Pereira, R.N.; Niesar, S.; Wiggers, H.; Brandt, M.S.; Stutzmann, M.S. Depassivation kinetics in crystalline silicon nanoparticles. Phys. Rev. B 2013, 88, 155430, doi:10.1103/physrevb.88.155430.
  99. Rohrer, M.; Bauer, H.; Mintorovitch, J.; Requardt, M.; Weinmann, H.-J. Comparison of Magnetic Properties of MRI Contrast Media Solutions at Different Magnetic Field Strengths. Investig. Radiol. 2005, 40, 715–724, doi:10.1097/01.rli.0000184756.66360.d3.
  100. Araki, K.; Uchiyama, M.K.; Toma, S.; Rodrigues, S.F.; Shimada, A.L.B.; Loiola, R.A.; Rodríguez, H.J.C.; Oliveira, P.V.; Luz, M.S.; Rabbani, S.R.; et al. Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool. Int. J. Nanomed. 2015, 10, 4731–4746, doi:10.2147/IJN.S83150.
  101. Kargina, Y.V.; Perepukhov, A.M.; Kharin, A.Y.; Zvereva, E.A.; Koshelev, A.V.; Zinovyev, S.V.; Maximychev, A.V.; Alykova, A.F.; Sharonova, N.V.; Zubov, V.P.; et al. Silicon Nanoparticles Prepared by Plasma‐Assisted Ablative Synthesis: Physical Properties and Potential Biomedical Applications. Phys. Status Solidi A 2019, 216, 1800897, doi:10.1002/pssa.201800897.
  102. Noginova, N.; Chen, F.; Weaver, T.; Giannelis, E.P.; Bourlinos, A.B.; Atsarkin, V.A. Magnetic resonance in nanoparticles: Between ferro- and paramagnetism. J. Phys. Condens. Matter 2007, 19, 246208, doi:10.1088/0953-8984/19/24/246208.
  103. Kargina, Y.V.; Zinovyev, S.V.; Perepukhov, A.M.; Suslova, E.V.; Ischenko, A.A.; Timoshenko, V.Y. Silicon nanoparticles with iron impurities for multifunctional applications. Funct. Mater. Lett. 2020, 13, 2040007, doi:10.1142/s179360472040007x.
  104. Bouchoucha, M.; Van Heeswijk, R.B.; Gossuin, Y.; Kleitz, F.; Fortin, M.-A. Fluorinated Mesoporous Silica Nanoparticles for Binuclear Probes in 1H and 19F Magnetic Resonance Imaging. Langmuir 2017, 33, 10531–10542, doi:10.1021/acs.langmuir.7b01792.
  105. Greish, Kh. Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting, Methods Mol. Biol. 2010, 624, 25–37, doi:10.1007/978-1-60761-609-2_3.
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