Your browser does not fully support modern features. Please upgrade for a smoother experience.
Extraction Chromatography: Comparison
Please note this is a comparison between Version 2 by Helena Kang and Version 1 by Helena Kang.

An extractant dissolved or impregnated in a porous inert support, rather than a covalently bonded ion-exchange group, constitutes the stationary phase of extraction chromatography. The mobile phase is typically an aqueous acid or salt solution; the target ion or molecule partitions into the supported organic extractant according to the same equilibria that govern liquid–liquid extraction, and is later stripped by a change of aqueous composition [1]. Crown ethers, organophosphorus acids, and related extractants provide selective coordination environments for strontium, actinides, and other species [2]. The technique is thereby a chromatographic embodiment of solvent extraction, distinct from solid-phase extraction that uses a dry sorbent without a liquid extractant film, and from reversed-phase chromatography whose retention is not based on a designed extractant–metal or extractant–solute complex [3]. Essential features are a defined extractant, a support that holds that extractant without dominating selectivity, and a reversible partition that can be reset by the aqueous eluent. Conceptual boundaries also exclude ordinary adsorption chromatography on bare silica or alumina.

  • extraction chromatography
  • supported extractant
  • partition
  • radiochemical separation

Chromatography in Natural Products • Analytical Chemistry • Chemistry • Physical Sciences

References

  1. E. Philip. Horwitz; Mark L. Dietz; Dan E. Fisher; Separation and preconcentration of strontium from biological, environmental, and nuclear waste samples by extraction chromatography using a crown ether. Anal. Chem. 1991, 63, 522-525. [CrossRef]
  2. V. Radchenko; J.W. Engle; J.J. Wilson; J.R. Maassen; F.M. Nortier; W.A. Taylor; E.R. Birnbaum; L.A. Hudston; K.D. John; M.E. Fassbender; Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes. J. Chromatogr. A 2015, 1380, 55-63. [CrossRef]
  3. Ian D. Wilson; J. K. Nicholson; Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine. Anal. Chem. 1987, 59, 2830-2832. [CrossRef]
More
Write an Entry