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Contemporary Themes in Geographic Epidemiology
Academic Editor: Peter Congdon
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Topic review
Updated time: 27 Apr 2021
Submitted by: Yong Zhou
Definition: Influenza A virus (IAV) is an important zoonotic pathogen that can cause disease in animals such as poultry and pigs and can cause infection and even death in humans, posing a serious threat to public health. IAV is an enveloped virus that relies on host cell metabolic systems, especially lipid metabolism systems, to complete its life cycle in host cells. On the other side, host cells regulate their metabolic processes to prevent IAV replication and maintain their normal physiological functions. This review summarizes the roles of fatty acid, cholesterol, phospholipid and glycolipid metabolism in IAV infection, proposes future research challenges, and looks forward to the prospective application of lipid metabolism modification to limit IAV infection, which will provide new directions for the development of anti-influenza drugs.
Topic review
Updated time: 01 Jun 2021
Submitted by: Muhammad Umer
Definition: In the wake of the COVID-19 pandemic, it is crucial to assess the application of a multitude of effective diagnostic specimens for conducting mass testing, for accurate diagnosis and to formulate strategies for its prevention and control. As one of the most versatile and amenable specimen options, saliva offers great advantages for widespread screening strategies due to its non-invasive properties, cost-effectiveness, excellent stability and minimal risk of cross-infection.