Browse by Subjects
Depression and treatment

Depression and treatment

Submit
Sort:
Show:
Page Size:
Topic review
Updated time: 05 Feb 2021
Submitted by: Edna Soares
Definition: It sheds light on the triad "physical exercise-extracellular vesicles-depression" and suggests new avenues in this novel emerging field.
Entry Collection : Depression and treatment
Unfold
Topic review
Updated time: 19 Jul 2021
Submitted by: Chieh-Hsin Lin
Definition: Late-life depression (LLD), compared to depression at a young age, is more likely to have poor prognosis and high risk of progression to dementia. A recent systemic review and meta-analysis of the present antidepressants for LLD showed that the treatment response rate was 48% and the remission rate was only 33.7%, thus implying the need to improve the treatment with other approaches in the future. Recently, agents modulating the glutamatergic system have been tested for mental disorders such as schizophrenia, dementia, and depressive disorder.
Entry Collection : Depression and treatment
Unfold
Topic review
Updated time: 15 Jun 2021
Submitted by: Elena Filatova
Definition: Major depressive disorder (MDD) is a heterogeneous disease that affects one out of five individuals in their lifetime and is the leading cause of disability worldwide. The symptoms of MDD are associated with structural and neurochemical deficits in the corticolimbic brain regions. The behavioral symptoms of depression are extensive, covering emotional, motivational, cognitive, and physiological domains, and include anhedonia, aberrant reward-associated perception, and memory alterations. Presently, MDD is considered a multifactorial disease with various causes and triggers such as genetic susceptibility, stress, and other pathological processes such as inflammation.
Entry Collection : Depression and treatment
Unfold
Topic review
Updated time: 07 Jul 2021
Submitted by: Marek Krzystanek
Definition: Treatment with antidepressants is often insufficiently effective, especially in treatment-resistant depression. In such a situation, it is possible to change the drug, add a second antidepressant, or use pharmacological and non-pharmacological methods of augmenting the effect of pharmacotherapy. New methods that may fall into the scope of multi-module depression treatment as an augmentation of depression treatment are whole body cryotherapy (WBC) and hyperbaric oxygen treatment (HBOT). 545 records were selected and analyzed for these two treatments and finally three clinical trials were selected for analysis.
Entry Collection : Depression and treatment
Unfold