Topic Review
The possibility of moving objects accessing different types of points of interest (POI) at specific time is not always the same, so quantitative time geography research needs to consider the actual POI semantic information, including POI attributes and time information.
  • 191
  • 22 Jan 2024
Topic Review
Intelligent question answering system is an innovative information service system which integrates natural language processing, information retrieval, semantic analysis and artificial intelligence. The system mainly consists of three core parts, which are question analysis, information retrieval and answer extraction. Through these three parts, the system can provide users with accurate, fast and convenient answering services.
  • 191
  • 21 Feb 2024
Topic Review
ω-3 PUFA on colon cancer
Substantial human and animal studies support the beneficial effects of ω-3 polyunsaturated fatty acids (PUFAs) on colonic inflammation and colorectal cancer (CRC). However, there are inconsistent results, which have shown that ω-3 PUFAs have no effect or even detrimental effects, making it difficult to effectively implement ω-3 PUFAs for disease prevention. A better understanding of the molecular mechanisms for the anti-inflammatory and anticancer effects of ω-3 PUFAs will help to clarify their potential health-promoting effects, provide a scientific base for cautions for their use, and establish dietary recommendations.
  • 897
  • 17 Nov 2020
Topic Review
Τhe “GPS/GNSS on Boat” Technique
The opening up of the global positioning system (GPS) for non-military uses provided a new impetus for the study of the sea surface topography (SST) and geoid, especially in coastal areas which are important from the viewpoint of the climate crisis. The application of the “GPS/GNSS on boat” method, as an alternative to traditional (indirect and direct) methods, has provided detailed SST maps in coastal and oceanic areas with an accuracy of up to few centimeters.
  • 551
  • 06 Jan 2023
Topic Review
σ-hole is a region of depleted electronic density located on the outer side of a covalently-bonded atom, situated roughly along an extension of the bond axis  
  • 1.4K
  • 24 May 2021
Topic Review
μ-Recursive Function
In mathematical logic and computer science, the general recursive functions (often shortened to recursive functions) or μ-recursive functions are a class of partial functions from natural numbers to natural numbers that are "computable" in an intuitive sense. In computability theory, it is shown that the μ-recursive functions are precisely the functions that can be computed by Turing machines(this is one of the theorems that supports the Church–Turing thesis). The μ-recursive functions are closely related to primitive recursive functions, and their inductive definition (below) builds upon that of the primitive recursive functions. However, not every μ-recursive function is a primitive recursive function—the most famous example is the Ackermann function. Other equivalent classes of functions are the λ-recursive functions and the functions that can be computed by Markov algorithms. The subset of all total recursive functions with values in {0,1} is known in computational complexity theory as the complexity class R.
  • 2.1K
  • 01 Dec 2022
Topic Review
κ-Opioid Receptor Agonists
The κ-opioid receptor (KOR) belongs to the class of inhibitory G protein-coupled receptors (GPCRs), widely expressed throughout the central nervous system and peripheral tissues. Due to the implications of KOR activation, KOR agonists have attracted recent attention for their ability to produce analgesia without the harmful side effects typically associated with MOR activation. In addition, KOR agonists show the potential for the treatment of pruritis, multiple sclerosis, Alzheimer’s disease, immune mediated diseases such as osteoarthritis, atopic dermatitis, food allergy, gastrointestinal diseases, cancer, hypoxia and ischemia.
  • 546
  • 20 Feb 2023
Topic Review
In precise timekeeping, ΔT (Delta T, delta-T, deltaT, or DT) is a measure of the cumulative effect of the departure of the Earth's rotation period from the fixed-length day of atomic time. Formally it is the time difference obtained by subtracting Universal Time (UT, defined by the Earth's rotation) from Terrestrial Time (TT, independent of the Earth's rotation): ΔT = TT − UT. The value of ΔT for the start of 1902 was approximately zero; for 2002 it was about 64 seconds. So the Earth's rotations over that century took about 64 seconds longer than would be required for days of atomic time. As well as this long-term drift in the length of the day there are short-term fluctuations in the length of day (Δτ) which are dealt with separately.
  • 834
  • 01 Nov 2022
Topic Review
Somatostatin-secreting δ-cells have aroused great attention due to their powerful roles in coordination of islet insulin and glucagon secretion and maintenance of glucose homeostasis. δ-cells exhibit neuron-like morphology with projections which enable pan-islet somatostatin paracrine regulation despite their scarcity in the islets. 
  • 570
  • 06 Apr 2021
Topic Review
γδ T Cells in Hepatocellular Carcinoma Immunotherapy
Hepatocellular carcinoma (HCC) remains a global health challenge with limited treatment options and a poor prognosis for advanced-stage patients. Recent advancements in cancer immunotherapy have generated significant interest in exploring novel approaches to combat HCC. One such approach involves the unique and versatile subset of T cells known as γδ T cells. γδ T cells represent a distinct subset of T lymphocytes that differ from conventional αβ T cells in terms of antigen recognition and effector functions. They play a crucial role in immunosurveillance against various malignancies, including HCC.
  • 240
  • 30 Jan 2024
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