Topic Review
Biological Function of Plant-Derived Exosome-like Nanovesicle
Plant-derived exosome-like nanovesicles (PELNs) are bilayer membrane-enclosed nanovesicles secreted by plant cells, serving as carriers of various substances such as proteins, RNA, and metabolites. The mounting evidence suggests that PELN plays a crucial role in transmembrane signaling, nutrient transportation, apoptosis, and regulation of gut microbiota composition. This makes it a promising “dark nutrient” for plants to modulate human physiology and pathogenesis.
  • 77
  • 02 Apr 2024
Topic Review
Assisted Robots in Therapies for Children
Children with autism spectrum disorder (ASD) have deficits that affect their social relationships, communication, and flexibility in reasoning. There are different types of treatment (pharmacological, educational, psychological, and rehabilitative). Currently, one way to address this problem is by using robotic systems to address the abilities that are altered in these children.
  • 58
  • 18 Mar 2024
Topic Review
Biocidal Action of Hydrogen Peroxide Vapour and Mechanism
Disinfection is described as a process that eliminates many or all pathogenic microorganisms on inanimate objects, with the exception of bacterial endospores. Disinfection is usually carried out by chemical or physical means. Among other settings, disinfection is of utmost importance in hospital environments due to pathogens living on hospital surfaces being the direct cause for hospital-acquired infections (HAIs). However, the presence of a wide range of pathogens and biofilms, combined with the indiscriminate use of antibiotics, presents infection control teams in healthcare facilities with ongoing challenges in the selection of biocides and application methods. This necessitates the development of biocides and innovative disinfection methods that overcome the shortcomings of conventional methods. The use of hydrogen peroxide vapour to be a superior alternative to conventional methods. Hydrogen peroxide vapour to be very close to an ideal disinfectant due to its proven efficacy against a wide range of microorganisms, safety to use, lack of toxicity concerns and good material compatibility.
  • 79
  • 14 Mar 2024
Topic Review
Application of IoT in Virus Detection
Today, healthcare system models should have high accuracy and sensitivity so that patients do not have a misdiagnosis. For this reason, sufficient knowledge of the area is required, with the medical staff being able to validate the correctness of their decisions. Therefore, artificial intelligence (AI) in combination with other emerging technologies could provide many benefits in the medical sector.
  • 91
  • 11 Mar 2024
Topic Review
Mendelian Susceptibility to Mycobacterial Disease
The diagnosis and treatment of patients with mendelian susceptibility to mycobacterial disease (MSMD) pose consistent challenges due to the diverse infection spectrum observed in this population. Common clinical manifestations include Bacillus Calmette-Guérin vaccine (BCG) complications in countries where routine BCG vaccination is practiced, while in non-BCG-vaccinating countries, Non-Tuberculous Mycobacteria (NTM) is prevalent. In tuberculosis-endemic regions, Mycobacterium tuberculosis (MTB) has a high prevalence, along with other intracellular organisms.
  • 162
  • 06 Mar 2024
Topic Review
Natural Products for Non-Alcoholic Fatty Liver Disease Treatment
Plants are an untapped natural resource; their secondary metabolites take part in a variety of pharmacological activities, making them an essential ingredient in the synthesis of novel medications and the source of reserve resources in this process. Hepatitis and liver cancer are two conditions that can result from non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition that now affects a significant section of the global population. There is a need for preventative action on predisposing factors. Due to their effectiveness and few side effects, herbal medications are frequently utilized for the prevention and treatment of NAFLD.
  • 79
  • 27 Feb 2024
Topic Review
Prebiotics and on Their Health Effects
Prebiotic compounds were originally defined as “a nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and thus improves host health”; however, a significant modulation of the definition was carried out in the consensus panel of The International Scientific Association for Probiotics and Prebiotics (ISAPP), and the last definition states that “prebiotics are substrates that are selectively utilized by host microorganisms conferring a health benefit”. 
  • 134
  • 26 Feb 2024
Topic Review
Endocrine Disruptors in Cosmetic Products and Regulatory Framework
Endocrine disruptors (EDs) are molecules capable of mimicking the natural hormones of the body and interfering with the endocrine system in both humans and wildlife. Cosmetic products are one source of EDs; these include an extensive variety of personal care and beauty products designed for the skin and hair, as well as makeup. The widespread use of such products has raised concerns about the presence of EDs within them.
  • 74
  • 26 Feb 2024
Topic Review
Milk-Derived Antiviral Peptides Targeting Zoonotic Viruses
Animals often serve as reservoirs for viral zoonoses, diseases transmissible from animals to humans. While zoonotic viral diseases have been present in human populations since the inception of agricultural practices, they have gained increasing prominence as a global public health concern, particularly with recent epidemics like SARS-CoV-2 (COVID-19). Some of these diseases are categorized as “emerging infectious diseases” due to their newfound recognition or significant changes in their range and epidemiology. Notable zoonotic diseases include influenza, Ebola virus, West Nile virus, emerging coronaviruses, monkeypox, rabies, Zika, and Lyme disease. Six out of every ten infectious diseases in humans are zoonotic, with many being viral. Therefore, it is imperative to enhance our capabilities to prevent and respond to these diseases, adopting a One Health approach. Finding new therapies and ways to prevent viral zoonoses is just as important as increasing efforts on surveillance and early detection, and with the rising amount of research demonstrating the potential of bioactive peptides produced from milk as antivirals, a vital opportunity arises to assess their usage in viral diseases with a focus on One Health. Indeed, several peptides derived from milk protein parents have shown potential for zoonotic viral diseases. 
  • 54
  • 20 Feb 2024
Topic Review
Nature-Based Interventions for Adults with Developmental Disabilities
Autistic adults often face higher levels of depression, anxiety, and stress and reduced levels of quality of life and employment in comparison to their neurotypical peers. Nature-based interventions (NBIs), which utilize outdoor environments and activities for health and wellbeing outcomes, could provide possibilities to meet these various needs.
  • 69
  • 18 Feb 2024
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