Topic Review
Documented Skeletal Collections in the United States
In the US, documented skeletal collections are a collective of human skeletons that originated (mostly) from body donations, human taphonomy facilities (e.g., the William M. Bass Donated Skeletal Collection), and anatomical dissections (e.g., Robert J. Terry Anatomical Collection). These collections are a major asset in the testing and development of methods used to infer the biological profile of human remains.
  • 918
  • 19 Apr 2022
Topic Review
Logistics Work, Ergonomics and Social Sustainability
The methodological basis is a load assessment of the musculoskeletal system in retail intralogistics. Based on the established measurements systems CUELA and OWAS, the specific loads on employees are assessed for four typical logistics workplace settings. 
  • 882
  • 16 Dec 2021
Topic Review
Combined Scientific and Artistic Approach
The main objective of this study was to propose a novel methodology to approach challenges in molecular biology. Akirin/Subolesin (AKR/SUB) are vaccine protective antigens and a model for the study of the interactome due to its conserved function in the regulation of different biological processes such as immunity and development throughout the metazoan. Herein, three visual artists and a music professor collaborated with scientists for the functional characterization of the AKR2 interactome in the regulation of the NF-kB pathway in human placenta cells. The results served as a methodological proof-of-concept to advance this research area. The results showed new perspectives on unexplored characteristics of AKR2 with functional implications. These results included protein dimerization, the physical interactions with different proteins simultaneously to regulate various biological processes defined by cell type-specific AKR-protein interactions and how these interactions positively or negatively regulate the Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-kB) signaling pathway in a biological context-dependent manner. These results suggested that AKR2 interacting proteins might constitute suitable secondary transcription factors for cell and stimulus-specific regulation of NF-kB. Musical perspective supported AKR/SUB evolutionary conservation in different species and provided new mechanistic insights into the AKR2 interactome. The combined scientific and artistic perspectives resulted in a multidisciplinary approach advancing our knowledge on AKR/SUB interactome and provided new insights into the function of AKR2-protein interactions in the regulation of the NF-kB pathway. Additionally, herein we proposed an algorithm for quantum vaccinomics by focusing on the model proteins AKR/SUB. This study was recently accepted for publication in Vaccines (Artigas-Jerónimo, S., Pastor Comín, J.J., Villar, M., Contreras, M., Alberdi, P., León Viera, I., Soto, L., Cordero, R., Valdés, J.J., Cabezas-Cruz, A., Estrada-Peña, A., de la Fuente, J. 2020. A novel combined scientific and artistic approach for advanced characterization of interactomes: the Akiri/Subolesinn model. Vaccines 8, 77)
  • 872
  • 29 Oct 2020
Topic Review
Montology
"Montology" is the holistic, integrative and transdisciplinary science of mountains, inclusive of physical, social, theoretical and empirical disciplines, as well as humanities and arts associated with mountainscapes.
  • 850
  • 29 Oct 2020
Topic Review
Public Attitudes towards COVID-19 Vaccination
Major hindrances to getting a COVID-19 vaccine include vaccine hesitancy, skepticism, refusal, and anti-vaccine movements. Several studies have been conducted on attitudes of the public towards COVID-19 vaccines and the potential influencing factors.
  • 825
  • 01 Jun 2021
Topic Review
Soundscape archaeology
Through an approach that aims to recognise and investigate the religious and public spaces of the past as “embodied spaces” and “sensory artefacts”, we can raise hypotheses on the sound experience in the ancient world and on the complex relationship between spaces and social interactions, making use of the potential provided by the application of 3D technology to virtual acoustics.  
  • 784
  • 27 Oct 2021
Topic Review
Historical Ecology in Brazil
The term “Historical Ecology” has been defined by two different research scholarships: (1) as a field that draws upon diverse evidence to trace complex, long-term relationships between humanity and Earth; and (2) as a field related to evolutionary ecology and the use of phylogenetic systematics, which may or may not involve anthropogenic agency. Here we embrace and refer to the first definition. Hence, Historical Ecology is a multidisciplinary field (or research program) that investigates human-environment relationships resulting in continuous spatial, environmental, historical, and cultural interactions. Its primary focus is the physical evidence etched in the landscape. The use of landscape as an analytical framework and spatial unit is valuable and widely used in Historical Ecology.  
  • 742
  • 07 May 2022
Topic Review
Diet for Chronic Kidney Disease
Chronic kidney disease is a growing health crisis in the U.S. Diabetes and hypertension are the leading causes of CKD development; as the US is experiencing an increasing prevalence of both, CKD is expected to remain a critical national health issue. At ESRD, the kidneys have lost their ability function, and as a result, a series of malfunctions occur that lead to adverse health problems and health outcomes. Once diagnosed with ESRD, the patient either will be on dialysis for the rest of their life or receive a kidney transplant.
  • 718
  • 09 Oct 2021
Topic Review
The Water–Energy–Food Nexus Index
The water–energy–food (WEF) Nexus Index is a quantitative measure and representation of country-level WEF security based on 21 water, energy, and food security indicators. The WEF nexus has emerged as a leading tool for assessing integrated resource management strategies and for monitoring progress towards the WEF-related Sustainable Development Goals. A notable outcome of WEF nexus research has been the calculation of the global WEF Nexus Index, which provides a quantitative ranking of country-level WEF security for 170 nations.
  • 655
  • 11 Feb 2022
Topic Review
International Migration from (Anglophone) Cameroon
In Africa, international migration to the Global North is often interpreted as a means to achieve upward social mobility. This article highlights the importance of considering the socio-economic and political transformations that form migration aspirations, especially among African youths. Simultaneously, increasing restrictive migration regimes impacts the extent to which migrants can meet the clauses in the moral economy of migration in their origin communities. We focus on (Anglophone) Cameroon, where international migration is referred to as “bushfalling”. A person who migrates to a Western society desires or is expected to return home to share the wealth he/she has accumulated. This interpretation of migration forms different perspectives regarding migrants and guides expectations towards returned migrants. However, little is known on how these expectations are defined and redefined in the society of return. Based on focus group discussions conducted among local community members, we show that the expectations were guided by the visa regimes of destination countries. Moreover, successful returnees were defined by their ability to be visible and create an impact after return. Thus, this article contributes more broadly to an African perspective on the meaning and impact of return migration.
  • 646
  • 18 Jan 2022
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