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Topic Review
Unicompartmental Knee Replacement in Obese-Patients
Unicompartmental knee arthroplasty (UKA) is a valid treatment for end-stage knee osteoarthritis (OA), affecting a single femoro-tibial compartment. The popularity of unicompartmental knee replacement (UKR) has increased as excellent functional outcomes and survival have been reported in long-term follow-up studies. UKA has important advantages compared to total knee arthroplasty (TKA), including lower intraoperative blood loss and risk of transfusionas well as accelerated recovery.
  • 454
  • 27 Aug 2021
Topic Review
Umbilical Cord-Derived Wharton’s Jelly in Orthopedic Regenerative Medicine
Wharton’s jelly (WJ) is an allogenic tissue comprised of connective tissue located within the umbilical cord. Wharton’s jelly resists torsional and compressive stresses during fetal development levied upon the umbilical vessels. The primitive mesenchymal stem cells reside within the UC-derived WJ [15]. These perinatal MSCs resemble embryonic stem cells (ESCs) but exhibit many properties of adult MSCs. Wharton’s jelly-derived mesenchymal stem cells (WJSCs) exhibit lower expression levels of pluripotent markers compared to ESCs, indicating multipotency rather than pluripotency [16,17]. Wharton’s jelly contains the highest concentration of MSCs/mL compared to other tissue types.
  • 545
  • 08 Nov 2021
Topic Review
Ultrasound in Medial Epicondylalgia and Medial Elbow Pain
Medial epicondylalgia (ME), commonly known as “the golfer’s elbow”, typically develops in individuals who perform repetitive forearm movements and weight-bearing activities. It accounts for up to 20% of all epicondylitis cases and is most prevalent in particular sports and occupations.
  • 720
  • 18 Aug 2022
Topic Review
Ultrasonography for Injecting (Around) the Lateral Epicondyle
Lateral epicondylitis (LE) is a very common and painful condition seen in the daily practice of musculoskeletal physicians. Ultrasound-guided (USG) injections are commonly performed to manage the pain, promote the healing phase, and plan a tailored rehabilitation treatment. In this aspect, several techniques were described to target specific pain generators i the lateral elbow.
  • 266
  • 03 Mar 2023
Topic Review
Ultrafast Laser in Orthopedic Surgery
The potential of ultrafast lasers (pico- to femtosecond) in orthopedics-related procedures has been studied extensively for clinical adoption. As compared to conventional laser systems with continuous wave or longer wave pulse, ultrafast lasers provide advantages such as higher precision and minimal collateral thermal damages. Translation to surgical applications in the clinic has been restrained by limitations of material removal rate and pulse average power, whereas the use in surface texturing of implants has become more refined to greatly improve bioactivation and osteointegration within bone matrices.
  • 466
  • 07 May 2022
Topic Review
Treatment of Thumb Carpometacarpal Joint Osteoarthritis
Thumb carpometacarpal joint (CMCJ) arthritis is the second most common location for degenerative osteoarthritis in the wrist and hand and several surgical treatments have been proposed so far, from arthrodesis to motion sparing procedures—such as trapeziectomy alone or in combination with interposition of autograft, allograft and ligamentoplasty.
  • 390
  • 19 Apr 2022
Topic Review
Treatment of Acetabular Peri-Prosthetic Fractures
Acetabular peri-prosthetic fractures are rare but their incidence is rising due to the increased prevalence of total hip arthroplasty, the increasing life expectancy and the growing functional demand of an ageing population, the incidence of primary total hip arthroplasty is increasing. They are either intra-operative or post-operative and have various aetiologies. Several factors such as implant stability, bone loss, remaining bone stock, fracture pattern, timing, age and co-morbidities of the patients must be considered for adequate treatment. To date, the literature on this subject has been sparse and no universally recognized treatment algorithm exists. Their rarity makes them a little-known entity and their surgical management represents a challenge for most orthopaedic surgeons. 
  • 352
  • 31 May 2022
Topic Review
Trauma-Related Thoracic Outlet Syndrome
Thoracic outlet syndrome (TOS) is a group of symptoms that result from compression of the neurovascular bundle that exits the thoracic outlet. The thoracic outlet is defined as an anatomical area in the lower neck, extended from the supraclavicular fossa to the axilla, and consists of three main spaces, the interscalene triangle, the costoclavicular, and the subcoracoid space. These confined spaces go through relevant structures, which include the subclavian and axillary arteries, their venous counterparts, and the brachial plexus (BP).
  • 122
  • 07 Nov 2023
Topic Review
Tranexamic Acid in Anterior Cruciate Ligament Reconstruction
There are several papers that investigate the use of tranexamic acid (TXA) in anterior cruciate ligament reconstructions (ACLR) or other arthroscopic procedures, that show favorable results and little to no complications. In our systematic review we show that TXA use in arthroscopic ACLR decreases postoperative blood loss and pain. Some evidence of improvement in functional scores were observed, but we believe that needs to be addressed in specific long-term result studies.
  • 276
  • 12 Jan 2022
Topic Review
Total Joint Arthroplasty Failure
Total joint arthroplasty is a common restorative surgery. Arthroplasty failure is a major complication of joint replacement surgery. It can be caused by periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical intervention and (in select scenarios) resection and reimplantation of implanted devices. Fast and accurate diagnosis of PJI and non-infectious arthroplasty failure (NIAF) is critical to direct medical and surgical treatment.
  • 285
  • 13 Feb 2023
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