Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
3D Printing in Hip Surgery
Three-dimensional printing, also known as additive manufacturing, is the process of creating objects from a 3D digital model layer by layer. Its origin dates back to 1984, when Chuck Hall developed his patent “Apparatus for production of three-dimensional objects by stereolithography”. There are many surgical applications of 3D printing in hip surgery, most of them based on CT images. 
  • 56
  • 04 Feb 2024
Topic Review
3D-Assisted Acetabular Fracture Surgery
The techniques currently used in 3D-assisted acetabular fracture surgery are 3D printing and visual surgical planning, 3D printing and pre-contouring of implants, and custom-made patient-specific implants. Three-dimensional-assisted surgery compared to conventional surgery reduces operation time, intraoperative blood loss, intraoperative fluoroscopy usage, and complication rate. Evidence for the improvement of postoperative fracture reduction and physical functioning is limited, because of heterogeneity and varying qualities of the studies.
  • 492
  • 28 Oct 2021
Topic Review
3D-Printed Porous Titanium Alloy Pore Structure onBone Regeneration
As a biomedical material, porous titanium alloy has gained widespread recognition and application within the field of orthopedics. Its remarkable biocompatibility, bioactivity, and mechanical properties establish it as a promising material for facilitating bone regeneration. A well-designed porous structure can lower the material’s modulus while retaining ample strength, rendering it more akin to natural bone tissue. The repair and replacement of a wide range of bone defects caused by diseases, trauma, and aging has been an important subject for centuries.
  • 40
  • 28 Feb 2024
Topic Review
3D-Printing Techniques for Surgical Planning in Orthopedic Surgery
Orthopedic oncology has begun to use three-dimensional-printing technology, which is expected to improve the accuracy of osteotomies, ensure a safe margin, and facilitate precise surgery. However, several difficulties should be considered.
  • 348
  • 18 Apr 2023
Topic Review
Achilles Tendinopathy Management
Achilles tendinopathy (AT) is a clinical condition characterized by persistent tendon pain and swelling related to mechanical loading of the Achilles tendon. AT, along with plantar fasciitis and stress fractures, are the injuries that most frequently involve the foot, furthermore AT is one of the most common tendinopathies of the lower limb .
  • 525
  • 21 Oct 2021
Topic Review
Adipose Tissue-Derived Mesenchymal Stem Cells and Cartilage Defects
Cartilage defects are a predisposing factor for osteoarthritis. Conventional therapies are mostly palliative and there is an interest in developing newer therapies that target the disease’s progression. Mesenchymal stem cells (MSCs) have been suggested as a promising therapy to restore hyaline cartilage to cartilage defects, though the optimal cell source has remained under investigation. Establishing standardised methods for MSC extraction and delivery, and performing studies with long follow-up should enable future high-quality research to provide the evidence needed to bring AMSC-based therapies into the market.
  • 429
  • 13 Dec 2021
Topic Review
Advance in Osteosarcoma Cells and Models
Osteosarcoma (OS) is not a uniform mass of cancer cells, but a complex, organ-like structure with diverse cell types influenced by various environmental factors. An individual with OS is subject to a multitude of complex biological, structural, mechanical, and soluble factors that may affect the effectiveness of potential therapeutics. Tumor-associated cells typically located in the vicinity of cancer cells include fibroblasts, immune cells, and endothelial cells. Structural factors include the architecture of the tumor itself (three-dimensionality), with the spherical nature of cell-to-cell interactions and the presence of extracellular matrix (ECM) key features. In addition, the mechanical forces applied by the surrounding microenvironment are important to tumor dynamics. Soluble factors may include gradients of chemicals, such as nutrients and gases, e.g., glucose and oxygen. Accordingly, the need for a more comprehensive range of OS models that precisely simulate this multifaceted tumor microenvironment is imperative for propelling advancements in drug discovery. 
  • 307
  • 27 Nov 2023
Topic Review
Albumin and Globulin for Diagnosing Periprosthetic Joint Infection
Periprosthetic joint infection (PJI) is one of the most intractable orthopedic diseases, partly because of the difficulty in differentiating septic from aseptic conditions. serum albumin (Alb), globulin (Glb), and Alb–Glb ratio (AGR) levels in combination with C-reactive protein (CRP) levels are feasible and accurate diagnostic markers for PJI and can improve the preoperative diagnostic accuracy of PJI.
  • 79
  • 15 Jan 2024
Topic Review
Analysis of the Classification Systems for Thoracolumbar Fractures
Spinal fractures represent a category of traumatic lesions with a significant impact both medical and social aspects of life. Within this category, thoracolumbar fractures (TLF) form a particular subcategory due to their location with specific biomechanics—the transition from thoracic physiologic kyphosis (fixed) to lumbar lordosis (mobile). Lesions at this level may have severe consequences such as complete/partial motor deficit, local pain or kyphosis.
  • 282
  • 30 May 2022
Topic Review
Ankle and Foot Arthroplasty and Prosthesis
The foot and ankle serve vital roles in weight bearing, balance, and flexibility but are susceptible to many diverse ailments, making treatment difficult. More commonly, Total Ankle Arthroplasty (TAA) and Total Talus Replacement (TTR) are used for patients with ankle degeneration and avascular necrosis of the talus, respectively. Ankle prosthesis and orthosis are also indicated for use with lower limb extremity amputations or locomotor disability, leading to the development of powered exoskeletons. However, patient outcomes remain suboptimal, commonly due to the misfitting of implants to the patient-specific anatomy. Additive manufacturing (AM) is being used to create customized, patient-specific implants and porous implant cages that provide structural support while allowing for increased bony ingrowth and to develop customized, lightweight exoskeletons with multifunctional actuators. AM implants and devices have shown success in preserving stability and mobility of the joint and achieving fast recovery, as well as significant improvements in gait rehabilitation, gait assistance, and strength for patients. 
  • 159
  • 20 Nov 2023
  • Page
  • of
  • 17
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Feedback