Topic Review
Carcino-Evo-Devo
The term “carcino-evo-devo” was used for the first time as a name for the theory of the evolutionary role of tumors. The new term was coined from two other terms: “carcinoembryonic” and “evo-devo”.
  • 233
  • 18 May 2023
Topic Review
Chlorophytum tuberosum
Chlorophytum tuberosum (C. tuberosum) belongs to the family Liliaceae and is being used in the indigenous systems of medicine as a galactagogue, aphrodisiac, antitumor, immunomodulatory, antidiabetic, analgesic, anti-inflammatory, hypolipidemic, anti-ageing, antimicrobial, etc. 
  • 558
  • 11 Apr 2023
Topic Review
Diopatra
The genus Diopatra is a major driver in sedimentary systems, altering the structure of habitats and changing the frequency of refugia and predator access to prey. It is taken as prey by a variety of shorebirds, crustaceans, and fish and used worldwide as bait.
  • 201
  • 05 Sep 2023
Topic Review
Ganoderma Triterpenoids and Their Bioactivities
Ganoderma has been used as a traditional medicine in Asian countries to prevent and treat various diseases. Numerous publications are stating that Ganoderma species have a variety of beneficial medicinal properties, and investigations on different metabolic regulations of Ganoderma species, extracts or isolated compounds have been performed both in vitro and in vivo.
  • 594
  • 11 Jan 2023
Topic Review
GJB2 Missense Variants
The GJB2 gene is the most common gene responsible for hearing loss (HL) worldwide, and missense variants are the most abundant type. GJB2 pathogenic missense variants cause nonsyndromic HL (autosomal recessive and dominant) and syndromic HL combined with skin diseases.
  • 177
  • 08 May 2023
Topic Review
Lemna Is Productive and Nutritious in Low Light
Land plants adjust growth rate, protein content, and antioxidant content in response to their environment. These acclimatory adjustments in plant form and function may require several days and development of a new leaf. An apparent lesser need for such acclimation is demonstrated here for the floating aquatic plant Lemna minor with a focus on its response to the growth light environment. Relevant features of L. minor include unusually high growth rates, photosynthetic capacities, and protein content coupled with the ability to produce high levels of photoprotective xanthophylls (which are essential human micronutrients) across a wide range of growth light environments without compromising photosynthetic efficiency.
  • 267
  • 26 May 2023
Topic Review
Mycobacterium tuberculosis as Modulators of Cell Death Mechanisms
Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host immune responses and favor its dissemination, a complex process of interest in pathogenesis-related studies. The main virulence factors of Mtb that alter cell death pathways are classified according to their origin as either non-protein (for instance, lipomannan) or protein (such as the PE family and ESX secretion system). The 38 kDa lipoprotein, ESAT-6 (early antigen-secreted protein 6 kDa), and another secreted protein, tuberculosis necrotizing toxin (TNT), induces necroptosis, thereby allowing mycobacteria to survive inside the cell. The inhibition of pyroptosis by blocking inflammasome activation by Zmp1 and PknF is another pathway that aids the intracellular replication of Mtb. Autophagy inhibition is another mechanism that allows Mtb to escape the immune response. The enhanced intracellular survival (Eis) protein, other proteins, such as ESX-1, SecA2, SapM, PE6, and certain microRNAs, also facilitate Mtb host immune escape process. 
  • 253
  • 04 Jul 2023
Topic Review
Rosmarinus officinalis in Cutaneous Diseases
The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. Rosmarinic acid, beyond its anti-infectious, antioxidant, anti-inflammatory and immunomodulatory properties, has been extensively investigated for its anti-cancer activity on various apparently functionally disconnected molecular targets leading to various types of cancer.
  • 214
  • 16 Jun 2023
Topic Review
Salicornia sp. pl. (Annual)
Salicornia, also commonly known as pickleweed, glasswort, sea asparagus and samphire, derives its name from the Latin word meaning “salt” and includes strictly halophytes.  Salicornia species thrive in littoral and coastal salt marsh or in inland salt pans, forming distinct vegetation types subjected to different flooding regimes with brackish-to-saline water (depending on tidal influences) and usually composed of almost monospecific plant communities; in general,  annual Salicornia occur in the innermost parts of the salt marshes, subject to longer periods of submersion. Asssregards their taxonomy, two series have been traditionally identified, diploid and tetraploid, each of them with numerous species and micro-species. Only three entities are recognized in the Mediterranean: Salicornia procumbens subsp. procumbens (tetraploid, distributed along Mediterranean and Atlantic coasts and including Salicornia emerici, Salicornia veneta and Salicornia dolichostachya), Salicornia perennans subsp. perennans (diploid, with Mediterranean and Eurasian distribution, including Salicornia patula) and Salicornia europaea subsp. europaea (diploid, western Mediterranean). They are almost all of food interest, because of herbaceous in consistency, and the tender tips of the young branches, that are harvested during summer and thean prepared i numerous  recipes based on geographic area of interest. Being therophytes, the only method of propagation is by the generative way (from seeds). Salicornia sp. pl. is cultivated on a commercial scale in Israel and in Mexico, the United Arab Emirates, Saudi Arabia and India. In many parts of the Europe, the use of this halophyte is mainly based on the harvesting of wild plants, while only in the Netherlands, Portugal and France are the plants of Salicornia sp. pl. cultivated. In Italy, the first attempts of S. patula cultivation for family consumption started over 40 years ago in the gardens located around the Lesina lagoon (Apulia, Southern Italy). Like other halophilic species, even in glassworts the stress of the alkaline environment induces the synthesis of metabolites that can be useful to humans for their antioxidant and anti-inflammatory power.
  • 503
  • 13 Feb 2023
Topic Review
Serendipita indica as a Growth Promoter
Serendipita indica has been found to be a prime beneficial microorganism that improved the growth and development of various plant species under normal and stress conditions. 
  • 558
  • 27 Dec 2022
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