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Topic Review Peer Reviewed
Buddhism in Addiction Recovery
Buddhism was established by Guatama Buddha as a practice to liberate sentient beings from suffering. Mindfulness-Based interventions (MBIs) are Western psychologists’ adaptation of mindfulness/Vipassana to treat mental illnesses. In addition to mindfulness, Buddhist recovery peer-support programs also adopt the Four Noble Truths, the Noble Eightfold Path, and the Five Precepts, which are the Buddha’s prescription to cease suffering and to discipline one’s ethical conduct.
  • 4.0K
  • 13 Apr 2022
Topic Review
OpenMP
OpenMP (Open Multi-Processing) is an application programming interface (API) that supports multi-platform shared-memory multiprocessing programming in C, C++, and Fortran, on many platforms, instruction-set architectures and operating systems, including Solaris, AIX, FreeBSD, HP-UX, Linux, macOS, and Windows. It consists of a set of compiler directives, library routines, and environment variables that influence run-time behavior. OpenMP is managed by the nonprofit technology consortium OpenMP Architecture Review Board (or OpenMP ARB), jointly defined by a broad swath of leading computer hardware and software vendors, including Arm, AMD, IBM, Intel, Cray, HP, Fujitsu, Nvidia, NEC, Red Hat, Texas Instruments, and Oracle Corporation. OpenMP uses a portable, scalable model that gives programmers a simple and flexible interface for developing parallel applications for platforms ranging from the standard desktop computer to the supercomputer. An application built with the hybrid model of parallel programming can run on a computer cluster using both OpenMP and Message Passing Interface (MPI), such that OpenMP is used for parallelism within a (multi-core) node while MPI is used for parallelism between nodes. There have also been efforts to run OpenMP on software distributed shared memory systems, to translate OpenMP into MPI and to extend OpenMP for non-shared memory systems.
  • 4.0K
  • 19 Oct 2022
Topic Review
Plants as anti-inflammatory drugs
Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet been studied chemically or biologically, particularly concerning anti-inflammatory action. Anti-inflammatory drugs can interfere in the pathophysiological process of inflammation, to minimize tissue damage and provide greater comfort to the patient. Therefore, it is important to note that due to the existence of a large number of species available for research, the successful development of new naturally occurring anti-inflammatory drugs depends mainly on a multidisciplinary effort to find new molecules. Although many review articles have been published in this regard, the majority presented the subject from a limited regional perspective.
  • 4.0K
  • 25 Aug 2020
Topic Review
Glutamatergic System in Depression
Major depressive disorder (MDD) is a heterogeneous neuropsychological disorder characterized by a combination of symptoms that negatively impact the productivity and well-being of inflicted patients, including impairments in cognition, emotional regulation, memory, motor function, motivation, and possible suicidal ideation. Glutamate is the major excitatory neurotransmitter in the central nervous system. It plays an important role in several physiological functions.
  • 4.0K
  • 11 May 2022
Topic Review
Stable Packaging and Producer Cell Lines for AAV
Today, recombinant adeno-associated virus (rAAV) vectors represent the vector systems which are mostly used for in vivo gene therapy for the treatment of rare and less-rare diseases. Although most of the past developments have been performed by using a transfection-based method and more than half of the authorized rAAV-based treatments are based on transfection process, the tendency is towards the use of stable inducible packaging and producer cell lines because their use is much more straightforward and leads in parallel to reduction in the overall manufacturing costs.
  • 4.0K
  • 29 Feb 2024
Topic Review
Psychiatric Survivors Movement
The psychiatric survivors movement (more broadly consumer/survivor/ex-patient movement) is a diverse association of individuals who either currently access mental health services (known as consumers or service users), or who are survivors of interventions by psychiatry, or who are ex-patients of mental health services. The psychiatric survivors movement arose out of the civil rights movement of the late 1960s and early 1970s and the personal histories of psychiatric abuse experienced by some ex-patients. The key text in the intellectual development of the survivor movement, at least in the USA, was Judi Chamberlin's 1978 text, On Our Own: Patient Controlled Alternatives to the Mental Health System. Chamberlin was an ex-patient and co-founder of the Mental Patients' Liberation Front. Coalescing around the ex-patient newsletter Dendron, in late 1988 leaders from several of the main national and grassroots psychiatric survivor groups felt that an independent, human rights coalition focused on problems in the mental health system was needed. That year the Support Coalition International (SCI) was formed. SCI's first public action was to stage a counter-conference and protest in New York City , in May, 1990, at the same time as (and directly outside of) the American Psychiatric Association's annual meeting. In 2005 the SCI changed its name to MindFreedom International with David W. Oaks as its director. Common themes are "talking back to the power of psychiatry", rights protection and advocacy, and self-determination. While activists in the movement may share a collective identity to some extent, views range along a continuum from conservative to radical in relation to psychiatric treatment and levels of resistance or patienthood.
  • 4.0K
  • 23 Nov 2022
Topic Review
Mount Tai
Mount Tai (Chinese: 泰山; pinyin: Tài Shān) is a mountain of historical and cultural significance located north of the city of Tai'an, it is the highest point in Shandong province, China. The tallest peak is the Jade Emperor Peak (simplified Chinese: 玉皇顶; traditional Chinese: 玉皇頂; pinyin: Yùhuáng Dǐng), which is commonly reported as being 1,545 meters (5,069 ft) tall, but is officially described by the PRC government as 1,532.7 meters (5,029 ft) tall. Mount Tai is known as the eastern mountain of the Sacred Mountains of China. It is associated with sunrise, birth, and renewal, and is often regarded the foremost of the five. Mount Tai has been a place of worship for at least 3,000 years and served as one of the most important ceremonial centers of China during large portions of this period. Because of its sacred importance and dramatic landscape, Promulgated by UNESCO as a Mixed Cultural and Natural Heritage in 1987. And it meets 7 of the 10 evaluation standards of World Heritage, and is listed as the World Heritage that meets the most standards along with the Tasmanian Wilderness World Heritage Area in Australia. An Earthquake or thunderstorm occurred in Mount Tai in 1831 BC or 1652 BC, also known as Mount Tai earthquake. First seen in "Bamboo Annals". At present, it is recognized by most scholars as the first recorded earthquake in Chinese history.
  • 4.0K
  • 10 Nov 2022
Topic Review
World
The World is the Earth and all life on it, including human civilization. In a philosophical context, the "world" is the whole of the physical Universe, or an ontological world (the "world" of an individual). In a theological context, the world is the material or the profane sphere, as opposed to the celestial, spiritual, transcendent or sacred spheres. "End of the world" scenarios refer to the end of human history, often in religious contexts. Human history is commonly understood as the history of humanity spanning the major geopolitical developments of about five millennia, from the first civilizations to the present. In terms such as world religion, world language, world government, and world war, the term world suggests an international or intercontinental scope without necessarily implying participation of every part of the world. The world population is the sum of all human populations at any time; similarly, the world economy is the sum of the economies of all societies or countries, especially in the context of globalization. Terms such as "world championship", "gross world product", and "world flags" imply the sum or combination of all sovereign states.
  • 4.0K
  • 17 Nov 2022
Topic Review
Clinoptilolite Characterization and EDS Analysis
Zeolites are materials of biomedical interest, in particular owing to their ability to remove metabolic products such as uremic toxins (i.e., urea, uric acid, creatinine, p-cresol, and indoxul sulfate); they are used for the regeneration of dialysis solutions and as in vivo membranes for artificial kidney. Zeolites have further important applications in the biomedical field, in fact they are used as hemostats (due to their ability to absorb water), antiseptics (when modified with silver or zinc ions), carriers for drugs and genes (adjuvant in vaccines), glucose absorbers, etc. Here, EDS microanalysis in the study of a sample of natural clinoptilolite is reported. 
  • 4.0K
  • 28 Sep 2021
Topic Review
Capture Myopathy in Spotted Deer
Capture myopathy is a noninfectious disease of the muscle associated with capturing or handling of any animals.
  • 4.0K
  • 17 Jun 2021
Topic Review
Synthesis of Hydrogels
Hydrogels are polymeric materials with a characteristic hydrophilic structure that enables the storage of large amounts of water and biological fluids in their three-dimensional (3D) network. For hydrogel synthesis, the incorporation of a cross-linking agent is important to achieve a better structuring due to its ability to form new polymeric chains within the structure through a large variety of reactions between different polymeric molecules or fibrous proteins.
  • 4.0K
  • 16 Aug 2022
Topic Review
Jump Scare
A jump scare (often shortened to jumpscare) is a technique often used in horror films, haunted attractions, video games, and Internet screamers, intended to scare the audience by surprising them with an abrupt change in image or event, usually co-occurring with a frightening sound, mostly loud screaming. Common in film since the 1980s, the jump scare has been described as "one of the most basic building blocks of horror movies". Jump scares can surprise the viewer by appearing at a point in the film where the soundtrack is quiet and the viewer is not expecting anything alarming to happen, or can be the sudden payoff to a long period of suspense. Some critics have described jump scares as a lazy way to frighten viewers, and believe that the horror genre has undergone a decline in recent years following an over-reliance on the trope, establishing it as a cliché of modern horror films.
  • 4.0K
  • 11 Oct 2022
Topic Review Peer Reviewed
The Capital Asset Pricing Model
The capital asset pricing model (CAPM) is an influential paradigm in financial risk management. It formalizes mean-variance optimization of a risky portfolio given the presence of a risk-free investment such as short-term government bonds. The CAPM defines the price of financial assets according to the premium demanded by investors for bearing excess risk.
  • 3.9K
  • 13 Apr 2022
Topic Review
N-Butanol
n-Butanol or n-butyl alcohol or normal butanol is a primary alcohol with a 4-carbon structure and the chemical formula C4H9OH. Its isomers include isobutanol, 2-butanol, and tert-butanol. Butanol is one of the group of "fusel alcohols" (from the German for "bad liquor"), which have more than two carbon atoms and have significant solubility in water. n-Butanol occurs naturally as a minor product of the fermentation of sugars and other carbohydrates, and is present in many foods and beverages. It is also a permitted artificial flavorant in the United States, used in butter, cream, fruit, rum, whiskey, ice cream and ices, candy, baked goods and cordials. It is also used in a wide range of consumer products. The largest use of n-butanol is as an industrial intermediate, particularly for the manufacture of butyl acetate (itself an artificial flavorant and industrial solvent). It is a petrochemical, manufactured from propylene and usually used close to the point of manufacture. Estimated production figures for 1997 are: United States 784,000 tonnes; Western Europe 575,000 tonnes; Japan 225,000 tonnes.
  • 3.9K
  • 26 Oct 2022
Topic Review
Synthesis of Mesoporous Silica Nanoparticles
Mesoporous silica nanoparticles (MSNs) have been advocated as nanocarriers for the treatment of various diseases because of their physicochemical properties and biocompatibility. The use of MSNs combined with therapeutic agents can provide better encapsulation and effective delivery. MSNs as nanocarriers might also be a promising tool to lower the therapeutic dosage levels and thereby to reduce undesired side effects. Furthermore, when combined with imaging compounds for diagnosis, they can be employed as theragnostic agents thus allowing both imaging and therapy using the same nanoparticle.
  • 3.9K
  • 19 Jul 2023
Topic Review
Cybersecurity Practices for Social Media Users
Cybersecurity is a collection of technologies established to protect the cyber environment of an individual user or organization. There are many cyber threats existing within the social media platform, such as loss of productivity, cyber bullying, cyber stalking, identity theft, social information overload, inconsistent personal branding, personal reputation damage, data breach, malicious software, service interruptions, hacks, and unauthorized access to social media accounts. It is also revealed that demographic factors, for example age, gender, and education level, may not necessarily be influential factors affecting the cyber awareness of the internet users.
  • 3.9K
  • 10 Feb 2022
Topic Review
Afrikaans Folklore
Learners of Afrikaans as an additional language could be enabled to respond to aesthetical, emotional, cultural and social values. Through the use of Afrikaans folklore teachers can focus on developing the learners' ability to behave with cultural and aesthetic sensitivity in different social contexts. Afrikaans examples of folklore are mentioned and discussed briefly to include stories with humour, magic, the transmission of social and cultural values and traditions, ecological meaning, idiomatic expressions, praise poems, ogre characters and stereotypes. By means of a well-known background and/or context of a text, learners of Afrikaans as an additional language can become aware of the aesthetic range of the target language; they can become acquainted with the depth and content of meaning implied in the text. If a text is understood, the reader becomes personally involved and this, in itself, can lead the reader to interact creatively with the text - from the mechanical aspect of the language system to the analytical aspect - where s/he can participate in the story. The learner can thus discover how the events unfold, s/he can share the characters' emotional experiences and communicate their personal responses. Herein lies the relevance of a good reading text (despite the origin) - because the reader inhabits the text and in the process the language becomes transparent.
  • 3.9K
  • 31 Oct 2022
Topic Review
Ramp Rate Limitation of Wind Power
A run for increasing the integration of renewable energy sources in the electricity network has been seen because of the big concern about environmental issues and pollution from controllable power units. Wind power is one of the most-used renewable energy sources, and the objective of limiting the ramp rate of the power output is to produce more stable power. The studies of ramp rate limitation applied in wind power production deal with the definition and detection of this phenomenon in the real data, the methodologies used to forecast it, its application for managing grids and microgrids, the different actions aimed at physically implementing the restriction, and some of the grid code requirements used in different nations.
  • 3.9K
  • 25 Oct 2022
Topic Review
Variable Speed Diesel Generators
Variable Speed Diesel Generators (VSDGs)  is a solution to optimize engine consumption and increase system efficiency during different regimes. It improves system behavior by adapting diesel generators (DGs) speed with demanded mechanical load from the generator. VSDG improves efficiency, increases engine lifetime, reduces fuel consumption, and GHG emissions. Conventional fixed speed DG can rarely operate at less than 50% of the maximal load, while VSDGs can operate for a long period at low rotational speed to support lower loads.
  • 3.9K
  • 19 Jan 2022
Topic Review
Ionizing Radiation
The development of protective agents against harmful radiations has been a subject of investigation for decades. However, effective (ideal) radioprotectors and radiomitigators remain an unsolved problem. Because ionizing radiation-induced cellular damage is primarily attributed to free radicals, radical scavengers are promising as potential radioprotectors. Early development of such agents focused on thiol synthetic compounds, e.g., amifostine (2-(3-aminopropylamino) ethylsulfanylphosphonic acid), approved as a radioprotector by the Food and Drug Administration (FDA, USA) but for limited clinical indications and not for nonclinical uses. To date, no new chemical entity has been approved by the FDA as a radiation countermeasure for acute radiation syndrome (ARS). All FDA-approved radiation countermeasures (filgrastim, a recombinant DNA form of the naturally occurring granulocyte colony-stimulating factor, G-CSF; pegfilgrastim, a PEGylated form of the recombinant human G-CSF; sargramostim, a recombinant granulocyte macrophage colony-stimulating factor, GM-CSF) are classified as radiomitigators. No radioprotector that can be administered prior to exposure has been approved for ARS. This differentiates radioprotectors (reduce direct damage caused by radiation) and radiomitigators (minimize toxicity even after radiation has been delivered). Molecules under development with the aim of reaching clinical practice and other nonclinical applications are discussed. Assays to evaluate the biological effects of ionizing radiations are also analyzed. Ionizing radiation is the energy released by atoms in the form of electromagnetic waves (e.g., X or gamma rays) or particle radiation (alpha, beta, electrons, protons, neutrons, mesons, prions, and heavy ions) with sufficient energy to ionize atoms or molecules.
  • 3.9K
  • 23 Feb 2022
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