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Topic Review
Customer-Relationship Management
Customer-relationship management (CRM) is an approach to manage a company's interaction with current and potential customers. It uses data analysis about customers' history with a company to improve business relationships with customers, specifically focusing on customer retention and ultimately driving sales growth. One important aspect of the CRM approach is the systems of CRM that compile data from a range of different communication channels, including a company's website, telephone, email, live chat, marketing materials and more recently, social media. Through the CRM approach and the systems used to facilitate it, businesses learn more about their target audiences and how to best cater to their needs.
  • 4.1K
  • 22 Nov 2022
Topic Review
Self-Amplifying mRNA Vaccine
The core principle behind mRNA vaccines is to encode the antigen in the mRNA and then to deliver the transcript to the host cell cytoplasm using a non-viral delivery system, allowing antigen expression and induction of an antigen-specific immune response. Self-amplifying RNA (saRNA) is a type of mRNA that also encodes viral replicase, which enables the RNA to self-replicate upon delivery into the cell.
  • 4.1K
  • 13 Feb 2021
Topic Review
Network Intrusion Detection Systems Using Artificial Intelligence/Machine Learning
The rapid growth of the Internet and communications has resulted in a huge increase in transmitted data. These data are coveted by attackers and they continuously create novel attacks to steal or corrupt these data. The growth of these attacks is an issue for the security of systems and represents one of the biggest challenges for intrusion detection. An intrusion detection system (IDS) is a tool that helps to detect intrusions by inspecting the network traffic. Although many researchers have studied and created new IDS solutions, IDS still needs improving in order to have good detection accuracy while reducing false alarm rates. 
  • 4.1K
  • 23 Dec 2022
Topic Review
Blairism
In British politics, Blairism is the political ideology of the former leader of the Labour Party and Prime Minister Tony Blair and those that follow him. It entered the New Penguin English Dictionary in 2000. Proponents of Blairism are referred to as Blairites.
  • 4.1K
  • 18 Oct 2022
Topic Review
Levels-of-Processing Effect
The levels-of-processing effect, identified by Fergus I. M. Craik and Robert S. Lockhart in 1972, describes memory recall of stimuli as a function of the depth of mental processing. Deeper levels of analysis produce more elaborate, longer-lasting, and stronger memory traces than shallow levels of analysis. Depth of processing falls on a shallow to deep continuum. Shallow processing (e.g., processing based on phonemic and orthographic components) leads to a fragile memory trace that is susceptible to rapid decay. Conversely, deep processing (e.g., semantic processing) results in a more durable memory trace. This theory contradicts the multi-store Atkinson-Shiffrin memory model which represents memory strength as being continuously variable, the assumption being that rehearsal always improves long-term memory. They argued that rehearsal that consists simply of repeating previous analyses (maintenance rehearsal) doesn't enhance long-term memory. In a study from 1975 (Craik and Tulving) participants were given a list of 60 words. Each word was presented along with three questions. The participant had to answer one of them. Those three questions were in one of three categories. One category of questions was about how the word was presented visually ("Is the word shown in italics?"). The second category of questions was about the phonemic qualities of the word ("Does the word begin with the sound 'bee'?"). The third category of questions was presented so that the reader was forced to think about the word within a certain context. ("Can you meet one in the street [a friend]"?) The result of this study showed that the words which contained deep processing (the latter) were remembered better.
  • 4.1K
  • 25 Oct 2022
Topic Review
Values in Action Inventory of Strengths
The VIA Inventory of Strengths (VIA-IS), formerly known as the "Values in Action Inventory," is a proprietary psychological assessment measure designed to identify an individual's profile of character strengths. It was created by Christopher Peterson and Martin Seligman, well-known researchers in the field of positive psychology, in order to operationalize their Character Strengths and Virtues Handbook (CSV). The CSV is the positive psychology counterpart to the Diagnostic and Statistical Manual of Mental Disorders (DSM) used in traditional psychology. Unlike the DSM, which scientifically categorizes human deficits and disorders, the CSV classifies positive human strengths. Moreover, the CSV is centered on helping people recognize and build upon their strengths. This aligned with the overall goal of the positive psychology movement, which aims to make people's lives more fulfilling, rather than simply treating mental illness. Notably, the VIA-IS is the tool by which people can identify their own positive strengths and learn how to capitalize on them.
  • 4.1K
  • 01 Dec 2022
Topic Review Peer Reviewed
The “Pink Tax” and Gender Price Disparity in Personal Care
The “Pink Tax” refers to charging higher prices for products and services marketed primarily to women compared to similar or identical items targeted at men, despite comparable production costs. This research uses Unilever as a case study to focus on the impact of the Pink Tax on women’s purchasing power, particularly within the personal care industry. The study provides a comprehensive overview of the Pink Tax’s evolution, key research findings, public responses, and regulatory measures to address this issue. By synthesising existing research and case studies, this paper highlights the economic burden imposed on women and the reinforcement of gender stereotypes through market practices. The study underscores the need for equitable pricing mechanisms and informed consumer advocacy to rectify the economic disparities exacerbated by the Pink Tax.
  • 4.1K
  • 27 Aug 2024
Topic Review
OER Electrocatalysts
The oxygen evolution reaction (OER) is the efficiency-determining half-reaction process of high-demand, electricity-driven water splitting due to its sluggish four-electron transfer reaction. Tremendous effects on developing OER catalysts with high activity and strong acid-tolerance at high oxidation potentials have been made for proton-conducting polymer electrolyte membrane water electrolysis (PEMWE), which is one of the most promising future hydrogen-fuel-generating technologies. Electrochemical water splitting involves two heterogeneous multi-step half-reactions, which are referred to as the cathodic hydrogen evolution reaction (HER) and the anodic oxygen evolution reaction (OER). An important frontier in OER electrocatalysis research is the development of the rational design of catalysts. Most of the excellent OER catalysts with high activity and durability are not stable in acidic solutions. They are easily oxidized and decomposed in a strong acid system, which is one of the indispensable working conditions for PEMWE.  Outstanding OER electrocatalysts should have excellent intrinsic activity and sufficient active sites, and these requirements are generally combined with simplicity and controllability.
  • 4.1K
  • 23 Jun 2021
Topic Review
Embodied 'Basic' Emotions in Chinese and English Language
References to the body are one feature shared across languages, particularly when describing the mental processes of emotion, reflecting the embodiment of an emotional experience. Embodied emotion concepts encompass these categorized outcomes of bidirectional brain–body interactions yet can be differentiated further into afferent or interoceptive and efferent or autonomic processes. Between languages, a comparison of emotion words indicates the dominance of afferent or interoceptive processes in how embodied emotions are conceptualized in Chinese, while efferent or autonomic processes feature more commonly in English. Correspondingly, in linguistic expressions of emotion, Chinese-speaking people are biased toward being more receptive, reflective, and adaptive, whereas native English speakers may tend to be more reactive, proactive, and interactive. 
  • 4.1K
  • 05 Aug 2022
Topic Review
Oral Hypoglycemic Agents
Diabetes mellitus (DM) is a chronic illness with an increasing global prevalence. More than 537 million cases of diabetes were reported worldwide in 2021, and the number is steadily increasing. The worldwide number of people suffering from DM is projected to reach 783 million in 2045. In 2021 alone, more than USD 966 billion was spent on the management of DM. Reduced physical activity due to urbanization is believed to be the major cause of the increase in the incidence of the disease, as it is associated with higher rates of obesity. Diabetes poses a risk for chronic complications such as nephropathy, angiopathy, neuropathy and retinopathy. Hence, the successful management of blood glucose is the cornerstone of DM therapy. The effective management of the hyperglycemia associated with type 2 diabetes includes physical exercise, diet and therapeutic interventions (insulin, biguanides, second generation sulfonylureas, glucagon-like peptide 1 agonists, dipeptidyl-peptidase 4 inhibitors, thiazolidinediones, amylin mimetics, meglitinides, α-glucosidase inhibitors, sodium-glucose cotransporter-2 inhibitors and bile acid sequestrants).
  • 4.1K
  • 15 Jun 2023
Topic Review
Eclipta prostrata (L.)L.(Asteraceae): Ethnomedicinal Uses and Chemical Constituents
Eclipta prostrata (L.) L. (Syn.: Eclipta alba (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and other countries.
  • 4.1K
  • 09 Dec 2021
Topic Review
Goose Bumps
Goose bumps, goosebumps or goose-pimples are the bumps on a person's skin at the base of body hairs which may involuntarily develop when a person is tickled, cold or experiencing strong emotions such as fear, euphoria or sexual arousal. The formation of goose bumps in humans under stress is considered to be a vestigial reflex. Its function in other apes is to raise the body's hair, and would have made human ancestors appear larger to scare off predators or to increase the amount of air trapped in the fur to make it more insulating. The reflex of producing goose bumps is known as piloerection or the pilomotor reflex, or, more traditionally, horripilation. It occurs in many mammals; a prominent example is porcupines, which raise their quills when threatened, or sea otters when they encounter sharks or other predators.
  • 4.1K
  • 29 Nov 2022
Topic Review
Right to Exist
The right to exist is said to be an attribute of nations. According to an essay by the nineteenth-century French philosopher Ernest Renan, a state has the right to exist when individuals are willing to sacrifice their own interests for the community it represents. Unlike self-determination, the right to exist is an attribute of states rather than of peoples. It is not a right recognized in international law. The phrase has featured prominently in the Arab–Israeli conflict since the 1950s. The right to exist of a de facto state may be balanced against another state's right to territorial integrity. Proponents of the right to exist trace it back to the "right of existence", said to be a fundamental right of states recognized by writers on international law for hundreds of years.
  • 4.1K
  • 16 Nov 2022
Topic Review
NRF2
Nuclear factor erythroid 2‐related factor 2 (NRF2) is a transcription factor that regulates the cellular defense against toxic and oxidative insults through the expression of genes involved in oxidative stress response and drug detoxification. NRF2 activation renders cells resistant to chemical carcinogens and inflammatory challenges. In addition to antioxidant responses, NRF2 is involved in other cellular processes, including metabolism and inflammation, and its functions are beyond the originally envisioned. NRF2 activity is tightly regulated through a complex transcriptional and post-translational network that enables it to orchestrate the cell’s response and adaptation to various pathological stressors for the homeostasis maintenance. Elevated or decreased NRF2 activity by pharmacological and genetic manipulations of NRF2 activation is associated with many metabolism- or inflammation-related diseases. Emerging evidence shows that NRF2 lies at the center of a complex regulatory network and establishes NRF2 as a truly pleiotropic transcription factor. Here we summarize the complex regulatory network of NRF2 activity and its roles in metabolic reprogramming, unfolded protein response, proteostatsis, autophagy, mitochondrial biogenesis, inflammation, and immunity.
  • 4.1K
  • 17 Jul 2020
Topic Review
Methanol to Gasoline (MTG)
The MTG (Methanol to Gasoline) process allows us to transform methanol into hydrocarbons within the range of gasoline boiling points.
  • 4.1K
  • 04 Mar 2022
Topic Review
Pascal's Wager
Pascal's Wager is an argument in philosophy presented by the seventeenth-century French philosopher, mathematician and physicist Blaise Pascal (1623–62). It posits that humans bet with their lives that God either exists or does not. Pascal argues that a rational person should live as though God exists and seek to believe in God. If God does not actually exist, such a person will have only a finite loss (some pleasures, luxury, etc.), whereas he stands to receive infinite gains (as represented by eternity in Heaven) and avoid infinite losses (eternity in Hell). Pascal's Wager was based on the idea of the Christian God, though similar arguments have occurred in other religious traditions. The original wager was set out in section 233 of Pascal's posthumously published Pensées ("Thoughts"). These previously unpublished notes were assembled to form an incomplete treatise on Christian apologetics. Historically, Pascal's Wager was groundbreaking because it charted new territory in probability theory, marked the first formal use of decision theory, and anticipated future philosophies such as existentialism, pragmatism and voluntarism.
  • 4.1K
  • 23 Nov 2022
Topic Review
Music and Sound Interventions for Post-Traumatic Stress Disorder
Post Traumatic Stress Disorder (PTSD) is characterized by symptoms including: intrusive memories, hyper-arousal, avoidance of trauma-related stimuli, and negative alterations in mood or cognition that develop following exposure to traumatic life events.
  • 4.1K
  • 15 Mar 2022
Topic Review
History of Intersex Surgery
The history of intersex surgery is intertwined with the development of the specialities of pediatric surgery, pediatric urology, and pediatric endocrinology, with our increasingly refined understanding of sexual differentiation, with the development of political advocacy groups united by a human qualified analysis, and in the last decade by doubts as to efficacy, and controversy over when and even whether some procedures should be performed. Prior to the medicalization of intersex, Canon and common law referred to a person's sex as male, female or hermaphrodite, with legal rights as male or female depending on the characteristics that appeared most dominant. The foundation of common law, the Institutes of the Lawes of England described how a hermaphrodite could inherit "either as male or female, according to that kind of sexe which doth prevaile." Single cases have been described by legal cases sporadically over the centuries. Modern ideas of medicalization of intersex and birth defects can be traced to French anatomist Isidore Geoffroy Saint-Hilaire (1805–1861), who pioneered the field of teratology. Since the 1920s surgeons have attempted to "fix" an increasing variety of conditions. Success has often been partial and surgery is often associated with minor or major, transient or permanent complications. Techniques in all fields of surgery are frequently revised in a quest for higher success rates and lower complication rates. Some surgeons, well aware of the immediate limitations and risks of surgery, feel that significant rates of imperfect outcomes are no scandal (especially for the more severe and disabling conditions). Instead they see these negative outcomes as a challenge to be overcome by improving the techniques. Genital reconstruction evolved within this tradition. In recent decades, nearly every aspect of this perspective has been called into question, with increasing concern regarding the human rights implications of medical interventions.
  • 4.1K
  • 01 Nov 2022
Topic Review
Sign Language Recognition Models
A hybrid system for sign language is a combination of both vision-sensor-based and combination of different sensors based models. 
  • 4.1K
  • 01 Jun 2022
Topic Review
Sex and Sexuality in Autism Spectrum Disorders
Autism spectrum disorder (ASD) consists of a set of permanent neurodevelopmental conditions, which are studded with social and communication differences, limited interests, and repetitive behaviors. Individuals with ASD have difficulty reading eye gestures and expressions, and may also have stereotyped or repetitive language, excessive adherence to routines, fixed interests, and rigid thinking. The relationship difficulties resulting from ASD do not allow individuals to relate adequately to others, leading to unwanted sexual contact, social isolation, and mental health disorders.
  • 4.1K
  • 14 Nov 2022
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