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Bioactive Properties in Brown Algae
Brown algae are a source of interesting natural bioactive compounds that could be employed in the development of new industrial applications. However, the bioactive compound content in algal extracts is highly dependent on the extraction method applied. Our research was focused on the effect of five different extracting solvents: EtOH, AcO, EtAc, Chl, and Hex, on the extraction yield, polyphenolic content, and antioxidant and antimicrobial activities of nine brown algae from the NW coastal region of the Iberian Peninsula. As expected, all parameters were significantly affected by the species and the nature of the extracting solvent. In fact, the highest extraction yield was achieved when ethanol was used as solvent. Nevertheless, regarding TPC, DPPH-RSA, and FRAP values, EtAc and AcO were reported to be the most effective solvents, depending on the algae assessed, which suggests a differential composition of brown macroalgae in terms of phenolic compounds with antioxidant activity. Concerning the extracts, the highest TPC and FRAP values were found for Ascophyllum nodosum using EtAc as solvent, showing a possible correlation between polyphenol production and antioxidant activity in terms of reducing power, while the highest DPPH-RSA values were achieved by Bifurcaria bifurcata extracted with hexane, thus suggesting the hydrophobic nature of the antioxidant produced by this species.
Algae are an underexploited source of natural bioactive compounds in Western countries, so an increasing interest in the valorization of these marine organisms has emerged in recent years. In this work, the effect of extracting solvent on the extraction yield, phenolic content, antioxidant capacity, and antimicrobial activity of nine brown macroalgae species (Ascophyllum nodosum, Himanthalia elongata, Undaria pinnatifida, Pelvetia canaliculata, Saccharina latissima, Bifurcaria bifurcata, Laminaria ochroleuca, Sargassum muticum, and Fucus spiralis) was assessed. Total phenolic content (TPC) and the antioxidant properties of extracts by different assays: radical scavenging activity (DPPH-RSA) and ferric reducing antioxidant power (FRAP) were performed. The antimicrobial activity of extracts was studied against six different foodborne microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Escherichia coli, Salmonella enteritidis, and Pseudomonas aeruginosa. The highest extraction yield was achieved in ethanolic extracts. However, the highest TPC and FRAP values were obtained on the ethyl acetate extracts, especially from A. nodosum. Concerning algal species, the highest TPC and FRAP values were found in A. nodosum, while the highest DPPH-RSA values were achieved in the hexane extracts of B. bifurcata. The antimicrobial activity of algal extracts varied according to the solvent and alga selected, suggesting the species- and solvent-dependent behavior of this property, with B. bifurcata extracts showing the highest results for a wide range of bacteria.
The entry is from 10.3390/foods10081915
- The European Food Safety Authority and European Centre for Disease Prevention and Control (EFSA and ECDC). The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017. EFSA J. 2018, 16, e05500.
- Stenfors Arnesen, L.P.; Fagerlund, A.; Granum, P.E. From soil to gut: Bacillus cereus and its food poisoning toxins. FEMS Microbiol. Rev. 2008, 32, 579–606.
- Parsaeimehr, A.; Lutzu, G.A. Algae as a Novel Source of Antimicrobial Compounds: Current and Future Perspectives. Current and Future Perspectives; Elsevier: Amsterdam, The Netherlands, 2016; ISBN 978-0-12803-668-6.
- Cardoso, S.M.; Carvalho, L.G.; Silva, P.J.; Rodrigues, M.S.; Pereira, O.R. Bioproducts from Seaweeds: A Review with Special Focus on the Iberian Peninsula. Curr. Org. Chem. 2014, 896–917.
- Yuan, Y.; Zhang, J.; Fan, J.; Clark, J.; Shen, P.; Li, Y.; Zhang, C. Microwave assisted extraction of phenolic compounds from four economic brown macroalgae species and evaluation of their antioxidant activities and inhibitory effects on α-amylase, α-glucosidase, pancreatic lipase and tyrosinase. Food Res. Int. 2018, 113, 288–297.
- Afonso, N.C.; Catarino, M.D.; Silva, A.M.S.; Cardoso, S.M. Brown macroalgae as valuable food ingredients. Antioxidants 2019, 8, 365.
- López-Hortas, L.; Domínguez, H.; Torres, M.D. Valorisation of edible brown seaweeds by the recovery of bioactive compounds from aqueous phase using MHG to develop innovative hydrogels. Process Biochem. 2019, 78, 100–107.
- Leandro, A.; Pereira, L.; Gonçalves, A.M.M. Diverse applications of marine macroalgae. Mar. Drugs 2020, 18, 17.
- García-Vaquero, M.; Ummat, V.; Tiwari, B.; Rajauria, G. Exploring Ultrasound, Microwave and Ultrasound—Microwave Assisted Extraction Technologies to Increase the Extraction of Bioactive Compounds and Antioxidants from Brown Macroalgae. Mar. Drugs 2020, 18, 172.
- Sornsiri, J.; Srisook, K.; Pornngam, P.; Sootanan, P. Prediction of biochemical mechanism of anti-inflammation explained from two marine-derived bioactive compounds. Agric. Nat. Resour. 2018, 52, 588–595.
- Tenorio-Rodríguez, P.A.; Esquivel-Solis, H.; Murillo-Álvarez, J.I.; Ascencio, F.; Campa-Córdova, Á.I.; Angulo, C. Biosprospecting potential of kelp (Laminariales, Phaeophyceae) from Baja California Peninsula: Phenolic content, antioxidant properties, anti-inflammatory, and cell viability. J. Appl. Phycol. 2019, 31, 3115–3129.
- Ford, L.; Stratakos, A.C.; Theodoridou, K.; Dick, J.T.A.; Sheldrake, G.N.; Linton, M.; Corcionivoschi, N.; Walsh, P.J. Polyphenols from Brown Seaweeds as a Potential Antimicrobial Agent in Animal Feeds. ACS Omega 2020.
- Buedenbender, L.; Astone, F.A.; Tasdemir, D. Bioactive Molecular Networking for Mapping the Antimicrobial Constituents of the Baltic Brown Alga Fucus vesiculosus. Mar. Drugs 2020, 18, 311.
- Santos, S.A.O.; Félix, R.; Pais, A.C.S.; Rocha, S.M.; Silvestre, A.J.D. The quest for phenolic compounds from macroalgae: A review of extraction and identification methodologies. Biomolecules 2019, 9, 847.
- Fernández-Segovia, I.; Lerma-García, M.J.; Fuentes, A.; Barat, J.M. Characterization of Spanish powdered seaweeds: Composition, antioxidant capacity and technological properties. Food Res. Int. 2018, 111, 212–219.
- Martínez–Hernández, G.B.; Castillejo, N.; Carrión–Monteagudo, M.d.M.; Artés, F.; Artés-Hernández, F. Nutritional and bioactive compounds of commercialized algae powders used as food supplements. Food Sci. Technol. Int. 2018, 24, 172–182.
- Buschmann, A.H.; Camus, C.; Infante, J.; Neori, A.; Israel, Á.; Hernández-González, M.C.; Pereda, S.V.; Gomez-Pinchetti, J.L.; Golberg, A.; Tadmor-Shalev, N.; et al. Seaweed production: Overview of the global state of exploitation, farming and emerging research activity. Eur. J. Phycol. 2017, 52, 391–406.
- García-Pérez, P.; Lozano-Milo, E.; Landín, M.; Gallego, P.P. Combining Medicinal Plant In Vitro Culture with Machine Learning Technologies for Maximizing the Production of Phenolic Compounds. Antioxidants 2020, 9, 210.